ENSG00000235954

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-7 / 7
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000425112	ENSG00000235954	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TTC28-AS1	lncRNA	lncRNA	12.92473	10.24729	13.5879	0.882897	0.209297	0.4067345	1.1766864	0.8058813	0.9836171	0.4032984	0.54641400	0.2843307	0.08665833	0.07516667	0.07200000	-0.003166667	1.000000e+00	4.991648e-13		FALSE
ENST00000436996	ENSG00000235954	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TTC28-AS1	lncRNA	retained_intron	12.92473	10.24729	13.5879	0.882897	0.209297	0.4067345	0.8881250	0.0000000	1.3680236	0.0000000	0.19827020	7.1064568	0.06006250	0.00000000	0.10080000	0.100800000	4.991648e-13	4.991648e-13		FALSE
ENST00000437713	ENSG00000235954	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TTC28-AS1	lncRNA	lncRNA	12.92473	10.24729	13.5879	0.882897	0.209297	0.4067345	4.2119018	3.8620176	6.4690359	0.4417267	0.04048787	0.7426936	0.32647500	0.37586667	0.47630000	0.100433333	5.959938e-02	4.991648e-13		FALSE
ENST00000454996	ENSG00000235954	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TTC28-AS1	lncRNA	lncRNA	12.92473	10.24729	13.5879	0.882897	0.209297	0.4067345	1.1285755	0.8150852	0.1417761	0.4451962	0.07143381	-2.4425989	0.08939167	0.08206667	0.01060000	-0.071466667	6.360838e-01	4.991648e-13		FALSE
ENST00000659843	ENSG00000235954	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TTC28-AS1	lncRNA	lncRNA	12.92473	10.24729	13.5879	0.882897	0.209297	0.4067345	0.9831710	1.0708848	0.7676894	0.3012304	0.03991201	-0.4749469	0.08050833	0.10900000	0.05646667	-0.052533333	3.873568e-01	4.991648e-13	FALSE	FALSE
ENST00000662329	ENSG00000235954	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TTC28-AS1	lncRNA	lncRNA	12.92473	10.24729	13.5879	0.882897	0.209297	0.4067345	1.4747515	1.3726700	1.2030519	0.1429745	0.28141166	-0.1888155	0.11412500	0.13583333	0.08830000	-0.047533333	3.891629e-01	4.991648e-13		FALSE
ENST00000662424	ENSG00000235954	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TTC28-AS1	lncRNA	lncRNA	12.92473	10.24729	13.5879	0.882897	0.209297	0.4067345	0.4132899	0.2081890	1.1627312	0.2081890	0.37086358	2.4262221	0.03222917	0.01740000	0.08583333	0.068433333	1.663387e-01	4.991648e-13		FALSE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 62
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groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000235954	E001	0.3289534	0.0297845639	9.495159e-01		22	27919376	27919383	8	+	0.117	0.127	0.135
ENSG00000235954	E002	0.3289534	0.0297845639	9.495159e-01		22	27919384	27919387	4	+	0.117	0.127	0.135
ENSG00000235954	E003	0.3289534	0.0297845639	9.495159e-01		22	27919388	27919391	4	+	0.117	0.127	0.135
ENSG00000235954	E004	0.7019140	0.0177520358	9.291457e-01	9.594463e-01	22	27919392	27919400	9	+	0.210	0.226	0.136
ENSG00000235954	E005	0.5546650	0.0214539523	5.158217e-01	6.504408e-01	22	27919401	27919403	3	+	0.118	0.226	1.137
ENSG00000235954	E006	1.3349293	0.0106175712	9.049313e-01	9.434881e-01	22	27919404	27919420	17	+	0.351	0.374	0.134
ENSG00000235954	E007	1.4821784	0.0094954515	8.395493e-01	8.997623e-01	22	27919421	27919422	2	+	0.407	0.374	-0.188
ENSG00000235954	E008	1.4821784	0.0094954515	8.395493e-01	8.997623e-01	22	27919423	27919428	6	+	0.407	0.374	-0.188
ENSG00000235954	E009	1.5574213	0.0084535368	2.555096e-01	3.924083e-01	22	27919429	27919432	4	+	0.502	0.306	-1.089
ENSG00000235954	E010	1.8572299	0.0096190734	3.137960e-01	4.564269e-01	22	27919433	27919436	4	+	0.542	0.373	-0.868
ENSG00000235954	E011	2.3042875	0.0275424495	2.725474e-01	4.114763e-01	22	27919437	27919437	1	+	0.614	0.431	-0.873
ENSG00000235954	E012	5.7173370	0.0030978715	6.844472e-01	7.874322e-01	22	27919438	27919456	19	+	0.858	0.810	-0.189
ENSG00000235954	E013	8.0348721	0.0021547619	7.662444e-01	8.488005e-01	22	27919457	27919465	9	+	0.943	0.979	0.133
ENSG00000235954	E014	8.6176392	0.0019388158	8.197621e-01	8.862216e-01	22	27919466	27919467	2	+	1.000	0.979	-0.081
ENSG00000235954	E015	8.7648882	0.0019541176	7.238526e-01	8.175790e-01	22	27919468	27919469	2	+	1.014	0.979	-0.129
ENSG00000235954	E016	8.7950772	0.0021978799	9.317917e-01	9.610262e-01	22	27919470	27919471	2	+	1.000	0.994	-0.024
ENSG00000235954	E017	12.5436026	0.0163094692	1.992232e-01	3.252576e-01	22	27919472	27919483	12	+	1.201	1.063	-0.498
ENSG00000235954	E018	15.2437520	0.0013952498	1.304021e-01	2.347222e-01	22	27919484	27919490	7	+	1.272	1.145	-0.451
ENSG00000235954	E019	15.4620767	0.0016711264	1.115678e-01	2.078573e-01	22	27919491	27919492	2	+	1.279	1.145	-0.475
ENSG00000235954	E020	18.9233762	0.0012014302	5.656296e-02	1.206966e-01	22	27919493	27919497	5	+	1.369	1.222	-0.512
ENSG00000235954	E021	18.2612161	0.0012626385	5.053171e-02	1.101063e-01	22	27919498	27919498	1	+	1.357	1.204	-0.535
ENSG00000235954	E022	58.4414968	0.0004332632	3.735944e-06	2.738386e-05	22	27919499	27919545	47	+	1.869	1.663	-0.698
ENSG00000235954	E023	1.8069671	0.0097126302	1.717379e-01	2.904750e-01	22	27919546	27919722	177	+	0.542	0.306	-1.279
ENSG00000235954	E024	2.8042344	0.0119271258	8.717997e-01	9.215429e-01	22	27919723	27919966	244	+	0.579	0.608	0.130
ENSG00000235954	E025	45.1507053	0.0005192468	2.700954e-07	2.522617e-06	22	27922018	27922021	4	+	1.783	1.519	-0.896
ENSG00000235954	E026	87.4749164	0.0022288332	1.533163e-06	1.223064e-05	22	27922022	27922178	157	+	2.039	1.842	-0.663
ENSG00000235954	E027	10.7749844	0.0016643131	1.573273e-02	4.213283e-02	22	27922179	27922227	49	+	1.184	0.946	-0.866
ENSG00000235954	E028	9.5121749	0.0060810636	2.337008e-02	5.851882e-02	22	27922228	27922241	14	+	1.138	0.893	-0.903
ENSG00000235954	E029	121.4132329	0.0043918902	6.971428e-03	2.114906e-02	22	27922242	27924346	2105	+	2.141	2.032	-0.365
ENSG00000235954	E030	104.5121272	0.0108700290	8.262591e-01	8.906685e-01	22	27924347	27924963	617	+	2.015	2.032	0.057
ENSG00000235954	E031	20.1224547	0.0009347644	8.356271e-01	8.971983e-01	22	27935151	27935230	80	+	1.320	1.338	0.064
ENSG00000235954	E032	0.0000000				22	27940018	27940019	2	+
ENSG00000235954	E033	5.1973046	0.0031129549	9.579496e-02	1.840799e-01	22	27940020	27940171	152	+	0.894	0.677	-0.866
ENSG00000235954	E034	0.0000000				22	27972521	27973089	569	+
ENSG00000235954	E035	42.7860702	0.0077342694	3.791356e-02	8.718241e-02	22	27985692	27986392	701	+	1.565	1.710	0.493
ENSG00000235954	E036	2.3313665	0.0081552437	4.940831e-01	6.310749e-01	22	27989882	27990026	145	+	0.457	0.571	0.549
ENSG00000235954	E037	1.4789707	0.1172648307	5.865981e-01	7.101324e-01	22	27990027	27990672	646	+	0.457	0.368	-0.485
ENSG00000235954	E038	0.6633060	0.0226195870	3.593125e-01	5.036601e-01	22	27991470	27992468	999	+	0.286	0.128	-1.448
ENSG00000235954	E039	0.1451727	0.0432696588	5.343117e-01		22	27992469	27992927	459	+	0.117	0.000	-9.472
ENSG00000235954	E040	0.0000000				22	27992928	27993112	185	+
ENSG00000235954	E041	0.0000000				22	27993113	27993123	11	+
ENSG00000235954	E042	1.3221552	0.0102274497	1.224512e-01	2.234403e-01	22	27993124	27993535	412	+	0.210	0.483	1.718
ENSG00000235954	E043	0.4427912	0.1710835874	6.543556e-01	7.645361e-01	22	27994473	27994473	1	+	0.210	0.126	-0.879
ENSG00000235954	E044	1.2876999	0.0102120649	4.130467e-01	5.565808e-01	22	27994474	27994559	86	+	0.286	0.432	0.870
ENSG00000235954	E045	1.2856235	0.0102124436	4.129182e-01	5.564764e-01	22	27994560	27994653	94	+	0.286	0.432	0.870
ENSG00000235954	E046	0.0000000				22	27994654	27994654	1	+
ENSG00000235954	E047	20.5044758	0.0010003894	7.575410e-01	8.423362e-01	22	27997411	27997739	329	+	1.345	1.325	-0.071
ENSG00000235954	E048	3.7118139	0.0626739143	9.870884e-01	9.959838e-01	22	27997740	27997985	246	+	0.675	0.676	0.008
ENSG00000235954	E049	10.1424921	0.0673501672	7.736566e-01	8.539603e-01	22	27997986	27998071	86	+	1.075	1.030	-0.162
ENSG00000235954	E050	9.7145633	0.0218103690	7.783270e-01	8.573487e-01	22	27998072	27998152	81	+	1.052	1.021	-0.113
ENSG00000235954	E051	6.9332676	0.0557113448	3.545661e-01	4.988808e-01	22	27998153	27998513	361	+	0.958	0.816	-0.540
ENSG00000235954	E052	2.5306380	0.2155536371	7.605288e-01	8.446117e-01	22	27998514	27998603	90	+	0.578	0.495	-0.389
ENSG00000235954	E053	12.3880876	0.0018579563	2.754267e-02	6.709627e-02	22	27998604	27998838	235	+	1.000	1.213	0.768
ENSG00000235954	E054	1.6389052	0.1938318897	4.502155e-01	5.913517e-01	22	27998839	27999243	405	+	0.503	0.365	-0.730
ENSG00000235954	E055	0.3697384	0.0248564251	1.766682e-01	2.969159e-01	22	27999395	27999429	35	+	0.000	0.226	9.866
ENSG00000235954	E056	52.9461552	0.0028391582	4.054244e-07	3.651017e-06	22	27999430	28000437	1008	+	1.565	1.838	0.927
ENSG00000235954	E057	28.9564697	0.0007960789	2.771412e-06	2.090360e-05	22	28000438	28000895	458	+	1.286	1.597	1.072
ENSG00000235954	E058	51.3920350	0.0077618643	5.539840e-06	3.903977e-05	22	28000896	28001658	763	+	1.546	1.839	0.991
ENSG00000235954	E059	38.0239068	0.0005622435	2.411810e-14	7.495246e-13	22	28001659	28002216	558	+	1.300	1.755	1.561
ENSG00000235954	E060	29.5107543	0.0007314030	1.568317e-09	2.243258e-08	22	28002217	28002483	267	+	1.234	1.636	1.387
ENSG00000235954	E061	11.6590766	0.0403823492	6.817781e-03	2.074873e-02	22	28002484	28002679	196	+	0.876	1.234	1.308
ENSG00000235954	E062	3.8664513	0.0052370209	6.992746e-01	7.990758e-01	22	28006529	28008581	2053	+	0.728	0.676	-0.216

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000235954

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3