ENSG00000235903

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000415033 ENSG00000235903 HEK293_OSMI2_2hA HEK293_TMG_2hB CPB2-AS1 lncRNA lncRNA 0.9050676 1.19684 0.9143283 0.6110062 0.04838655 -0.3847575 0.08708690 0.02072781 0.22176850 0.020727814 0.04168435 2.91506742 0.11430833 0.04156667 0.24366667 0.20210000 0.087602963 0.001173546   FALSE
ENST00000606351 ENSG00000235903 HEK293_OSMI2_2hA HEK293_TMG_2hB CPB2-AS1 lncRNA lncRNA 0.9050676 1.19684 0.9143283 0.6110062 0.04838655 -0.3847575 0.07312287 0.12643896 0.00000000 0.126438962 0.00000000 -3.77018378 0.09685417 0.18660000 0.00000000 -0.18660000 0.832707464 0.001173546   FALSE
ENST00000606991 ENSG00000235903 HEK293_OSMI2_2hA HEK293_TMG_2hB CPB2-AS1 lncRNA lncRNA 0.9050676 1.19684 0.9143283 0.6110062 0.04838655 -0.3847575 0.09542366 0.06794620 0.06649131 0.050647299 0.03484691 -0.02718278 0.13331250 0.11676667 0.06903333 -0.04773333 0.994517424 0.001173546   FALSE
ENST00000663015 ENSG00000235903 HEK293_OSMI2_2hA HEK293_TMG_2hB CPB2-AS1 lncRNA lncRNA 0.9050676 1.19684 0.9143283 0.6110062 0.04838655 -0.3847575 0.13308126 0.05836153 0.21958246 0.004235948 0.03921644 1.74775578 0.18223333 0.07926667 0.23836667 0.15910000 0.142976205 0.001173546   FALSE
ENST00000667409 ENSG00000235903 HEK293_OSMI2_2hA HEK293_TMG_2hB CPB2-AS1 lncRNA lncRNA 0.9050676 1.19684 0.9143283 0.6110062 0.04838655 -0.3847575 0.03601004 0.11196651 0.00000000 0.018840967 0.00000000 -3.60841321 0.05455000 0.16113333 0.00000000 -0.16113333 0.054278459 0.001173546 FALSE FALSE
ENST00000669053 ENSG00000235903 HEK293_OSMI2_2hA HEK293_TMG_2hB CPB2-AS1 lncRNA lncRNA 0.9050676 1.19684 0.9143283 0.6110062 0.04838655 -0.3847575 0.13395212 0.03246586 0.26936596 0.011569108 0.02749131 2.71778072 0.18306667 0.04683333 0.29460000 0.24776667 0.001173546 0.001173546 FALSE FALSE
ENST00000688731 ENSG00000235903 HEK293_OSMI2_2hA HEK293_TMG_2hB CPB2-AS1 lncRNA lncRNA 0.9050676 1.19684 0.9143283 0.6110062 0.04838655 -0.3847575 0.25996393 0.72057144 0.00000000 0.720571442 0.00000000 -6.19095346 0.10716667 0.29843333 0.00000000 -0.29843333 0.785194756 0.001173546   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000235903 E001 0.0000000       13 46052497 46052797 301 +      
ENSG00000235903 E002 0.0000000       13 46052798 46052805 8 +      
ENSG00000235903 E003 0.0000000       13 46052806 46052811 6 +      
ENSG00000235903 E004 0.1482932 0.041159753 2.963917e-01   13 46052812 46052818 7 + 0.000 0.153 10.465
ENSG00000235903 E005 0.3299976 0.027442404 9.664786e-02   13 46052819 46052833 15 + 0.000 0.267 13.413
ENSG00000235903 E006 0.3299976 0.027442404 9.664786e-02   13 46052834 46052839 6 + 0.000 0.267 13.413
ENSG00000235903 E007 0.4782907 0.021768165 3.215440e-02 7.615681e-02 13 46052840 46052840 1 + 0.000 0.356 13.927
ENSG00000235903 E008 0.4782907 0.021768165 3.215440e-02 7.615681e-02 13 46052841 46052845 5 + 0.000 0.356 13.927
ENSG00000235903 E009 0.6255398 0.019387492 1.393724e-01 2.471861e-01 13 46052846 46052849 4 + 0.097 0.356 2.350
ENSG00000235903 E010 1.4704484 0.009706951 1.583770e-02 4.237402e-02 13 46052850 46052866 17 + 0.176 0.599 2.574
ENSG00000235903 E011 2.5066159 0.006266485 3.357178e-01 4.795170e-01 13 46052867 46052876 10 + 0.476 0.643 0.766
ENSG00000235903 E012 5.7800056 0.003364737 1.359328e-01 2.423929e-01 13 46052877 46052965 89 + 0.739 0.937 0.767
ENSG00000235903 E013 0.3686942 0.075253688 7.055188e-01 8.038637e-01 13 46052966 46052969 4 + 0.097 0.154 0.776
ENSG00000235903 E014 8.0424734 0.002651046 3.851395e-02 8.830148e-02 13 46094853 46095002 150 + 0.844 1.080 0.883
ENSG00000235903 E015 0.2955422 0.028931125 7.203234e-01   13 46095003 46095843 841 + 0.097 0.153 0.766
ENSG00000235903 E016 0.0000000       13 46096277 46096531 255 +      
ENSG00000235903 E017 0.4847352 0.227168849 1.000000e+00 1.000000e+00 13 46096705 46097109 405 + 0.176 0.154 -0.232
ENSG00000235903 E018 0.9286724 0.015271656 2.643384e-01 4.022985e-01 13 46097110 46097360 251 + 0.352 0.154 -1.554
ENSG00000235903 E019 0.3268771 0.031330200 7.095824e-01   13 46097361 46097399 39 + 0.097 0.154 0.769
ENSG00000235903 E020 10.2263808 0.003882942 1.360746e-01 2.425796e-01 13 46098398 46098667 270 + 0.988 1.150 0.588
ENSG00000235903 E021 6.5997186 0.002607130 7.986494e-04 3.254641e-03 13 46098668 46098781 114 + 0.676 1.080 1.560
ENSG00000235903 E022 0.8877700 0.066633882 5.174192e-03 1.640174e-02 13 46098782 46098810 29 + 0.000 0.494 14.513
ENSG00000235903 E023 5.1784543 0.043058387 6.686088e-01 7.755785e-01 13 46098811 46101588 2778 + 0.812 0.779 -0.130
ENSG00000235903 E024 6.0353215 0.003159886 1.884487e-01 3.117749e-01 13 46104855 46106736 1882 + 0.902 0.754 -0.581
ENSG00000235903 E025 4.0523072 0.004324046 1.031462e-01 1.952687e-01 13 46113184 46113507 324 + 0.601 0.841 0.988
ENSG00000235903 E026 11.2913031 0.001756328 3.374992e-09 4.538810e-08 13 46113508 46117208 3701 + 1.254 0.599 -2.512
ENSG00000235903 E027 0.4482035 0.025940197 2.074458e-01 3.354397e-01 13 46118028 46118053 26 + 0.243 0.000 -12.891
ENSG00000235903 E028 8.2839781 0.004982976 5.171685e-06 3.668277e-05 13 46118054 46119996 1943 + 1.121 0.550 -2.261
ENSG00000235903 E029 9.4494786 0.003123023 2.942945e-01 4.354030e-01 13 46119997 46122679 2683 + 1.050 0.958 -0.342
ENSG00000235903 E030 0.0000000       13 46151494 46151576 83 +      
ENSG00000235903 E031 1.1178523 0.144616890 2.686627e-01 4.071430e-01 13 46158457 46161379 2923 + 0.398 0.155 -1.805