ENSG00000234072

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000453289 ENSG00000234072 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 17.43971 22.17058 12.4859 1.434538 0.1586596 -0.827842 0.6625877 0.5942307 1.112153 0.2284733 0.1426869 0.8930984 0.04080833 0.02686667 0.08883333 0.06196667 0.01461694 0.01461694    
MSTRG.18120.3 ENSG00000234072 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA   17.43971 22.17058 12.4859 1.434538 0.1586596 -0.827842 2.7451473 2.6913239 2.084281 0.6686302 0.3554374 -0.3672119 0.16752083 0.12080000 0.16750000 0.04670000 0.61369024 0.01461694    
MSTRG.18120.4 ENSG00000234072 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA   17.43971 22.17058 12.4859 1.434538 0.1586596 -0.827842 3.2753828 4.3136195 2.162446 0.8974390 1.1179623 -0.9929191 0.17784167 0.19110000 0.17156667 -0.01953333 0.87341581 0.01461694    
MSTRG.18120.9 ENSG00000234072 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA   17.43971 22.17058 12.4859 1.434538 0.1586596 -0.827842 9.2812667 11.9994396 6.086506 1.0944557 0.2876611 -0.9781144 0.52923333 0.54040000 0.48820000 -0.05220000 0.60292594 0.01461694    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000234072 E001 8.9007285 0.0102497553 0.9142192319 0.949670135 2 27356246 27356831 586 + 0.948 0.967 0.069
ENSG00000234072 E002 4.3418079 0.0036439307 0.1327095900 0.237870018 2 27356832 27356856 25 + 0.825 0.618 -0.852
ENSG00000234072 E003 15.1715951 0.0194302896 0.6794520828 0.783627125 2 27357013 27357067 55 + 1.201 1.165 -0.128
ENSG00000234072 E004 15.3481913 0.0129223499 0.3627606263 0.507187545 2 27357068 27357070 3 + 1.235 1.150 -0.301
ENSG00000234072 E005 37.3807587 0.0232277473 0.5959648692 0.717970650 2 27357071 27357139 69 + 1.567 1.538 -0.100
ENSG00000234072 E006 52.5328658 0.0118258328 0.9886372605 0.996951903 2 27357140 27357187 48 + 1.683 1.696 0.043
ENSG00000234072 E007 80.3232954 0.0062875250 0.2822432730 0.422214916 2 27357188 27357292 105 + 1.906 1.858 -0.163
ENSG00000234072 E008 59.7752221 0.0021337216 0.0207434903 0.053046516 2 27357293 27357347 55 + 1.818 1.708 -0.370
ENSG00000234072 E009 38.5165710 0.0006743506 0.0419827074 0.094693518 2 27357348 27357372 25 + 1.633 1.522 -0.381
ENSG00000234072 E010 70.4960237 0.0003645159 0.0056933839 0.017799470 2 27357808 27357900 93 + 1.892 1.781 -0.375
ENSG00000234072 E011 39.5366677 0.0005853964 0.0920581991 0.178322815 2 27357901 27357902 2 + 1.633 1.543 -0.308
ENSG00000234072 E012 300.1853195 0.0007246350 0.6299726853 0.745249154 2 27357903 27358816 914 + 2.431 2.448 0.055
ENSG00000234072 E013 65.6810169 0.0008207069 0.0001682461 0.000827674 2 27358817 27358884 68 + 1.646 1.835 0.639
ENSG00000234072 E014 121.3491982 0.0073438845 0.0363953701 0.084334178 2 27358885 27359460 576 + 1.972 2.086 0.385
ENSG00000234072 E015 92.2445497 0.0058618866 0.0545074611 0.117130545 2 27359461 27360256 796 + 1.862 1.968 0.357
ENSG00000234072 E016 0.8835061 0.2213259824 0.2027478217 0.329659768 2 27365083 27365158 76 + 0.439 0.168 -1.883
ENSG00000234072 E017 4.9593063 0.0297949541 0.6304019954 0.745584760 2 27367424 27367622 199 + 0.796 0.728 -0.273