ENSG00000233806

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000415434 ENSG00000233806 HEK293_OSMI2_2hA HEK293_TMG_2hB LINC01237 lncRNA lncRNA 0.6314521 0.6200005 0.3995106 0.1347719 0.05636462 -0.6214523 0.070126112 0.28092637 0.00000000 0.07934367 0.00000000 -4.86258216 0.11754583 0.4483667 0.0000000 -0.44836667 0.0005108361 0.0005108361   FALSE
ENST00000429947 ENSG00000233806 HEK293_OSMI2_2hA HEK293_TMG_2hB LINC01237 lncRNA lncRNA 0.6314521 0.6200005 0.3995106 0.1347719 0.05636462 -0.6214523 0.033848535 0.00000000 0.03080383 0.00000000 0.03080383 2.02870472 0.03669167 0.0000000 0.1007000 0.10070000 0.7456679910 0.0005108361   FALSE
ENST00000430555 ENSG00000233806 HEK293_OSMI2_2hA HEK293_TMG_2hB LINC01237 lncRNA lncRNA 0.6314521 0.6200005 0.3995106 0.1347719 0.05636462 -0.6214523 0.141115539 0.15219878 0.11125678 0.05750137 0.06873619 -0.41969762 0.23609167 0.3043000 0.2659667 -0.03833333 0.9517432603 0.0005108361   FALSE
ENST00000457686 ENSG00000233806 HEK293_OSMI2_2hA HEK293_TMG_2hB LINC01237 lncRNA lncRNA 0.6314521 0.6200005 0.3995106 0.1347719 0.05636462 -0.6214523 0.174378317 0.11853028 0.06183467 0.11853028 0.06183467 -0.83935610 0.22996667 0.1344667 0.1235000 -0.01096667 1.0000000000 0.0005108361   FALSE
ENST00000687670 ENSG00000233806 HEK293_OSMI2_2hA HEK293_TMG_2hB LINC01237 lncRNA lncRNA 0.6314521 0.6200005 0.3995106 0.1347719 0.05636462 -0.6214523 0.106983279 0.06834512 0.07097703 0.01130608 0.02335185 0.04766929 0.17276667 0.1129000 0.1679000 0.05500000 0.6942444341 0.0005108361   FALSE
ENST00000690485 ENSG00000233806 HEK293_OSMI2_2hA HEK293_TMG_2hB LINC01237 lncRNA lncRNA 0.6314521 0.6200005 0.3995106 0.1347719 0.05636462 -0.6214523 0.051795993 0.00000000 0.08820240 0.00000000 0.01218845 3.29575835 0.10141250 0.0000000 0.2228333 0.22283333 0.0040686538 0.0005108361   FALSE
ENST00000691382 ENSG00000233806 HEK293_OSMI2_2hA HEK293_TMG_2hB LINC01237 lncRNA lncRNA 0.6314521 0.6200005 0.3995106 0.1347719 0.05636462 -0.6214523 0.004554487 0.00000000 0.03643590 0.00000000 0.03643590 2.21524053 0.01488750 0.0000000 0.1191000 0.11910000 0.7456679910 0.0005108361   FALSE
ENST00000693709 ENSG00000233806 HEK293_OSMI2_2hA HEK293_TMG_2hB LINC01237 lncRNA lncRNA 0.6314521 0.6200005 0.3995106 0.1347719 0.05636462 -0.6214523 0.023021808 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.05683333 0.0000000 0.0000000 0.00000000   0.0005108361 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000233806 E001 0.0000000       2 241881363 241881365 3 +      
ENSG00000233806 E002 0.0000000       2 241881366 241881366 1 +      
ENSG00000233806 E003 2.1422727 0.009139780 0.11351344 0.21064738 2 241881367 241881474 108 + 0.301 0.587 1.520
ENSG00000233806 E004 0.6265839 0.023798869 0.04940409 0.10810058 2 241881475 241881478 4 + 0.000 0.355 12.516
ENSG00000233806 E005 0.0000000       2 241881948 241881952 5 +      
ENSG00000233806 E006 0.6685028 0.018841764 0.88466973 0.93026104 2 241881953 241882129 177 + 0.222 0.214 -0.066
ENSG00000233806 E007 0.0000000       2 241882425 241882559 135 +      
ENSG00000233806 E008 2.6279398 0.007708688 0.45418051 0.59484086 2 241882560 241882635 76 + 0.477 0.621 0.669
ENSG00000233806 E009 0.0000000       2 241933836 241934073 238 +      
ENSG00000233806 E010 0.8480291 0.015745748 0.02278517 0.05729926 2 241934074 241934210 137 + 0.000 0.413 12.786
ENSG00000233806 E011 0.0000000       2 241958859 241958933 75 +      
ENSG00000233806 E012 4.2039072 0.004140241 0.24519143 0.38026098 2 241965927 241966047 121 + 0.602 0.784 0.763
ENSG00000233806 E013 0.5869198 0.028372248 0.02622063 0.06439820 2 241966048 241966120 73 + 0.368 0.000 -12.900
ENSG00000233806 E014 1.0641663 0.023498856 0.18310568 0.30508811 2 241966121 241966328 208 + 0.426 0.214 -1.390
ENSG00000233806 E015 0.7696683 0.018088376 0.54395373 0.67448425 2 241966329 241966440 112 + 0.301 0.214 -0.653
ENSG00000233806 E016 1.8361239 0.009517378 0.58610925 0.70973511 2 241966588 241967452 865 + 0.477 0.414 -0.328
ENSG00000233806 E017 1.2920680 0.011100199 0.35416974 0.49843178 2 241967453 241967575 123 + 0.426 0.291 -0.803
ENSG00000233806 E018 1.4361966 0.010517370 0.05013693 0.10940714 2 241967576 241967717 142 + 0.523 0.214 -1.873
ENSG00000233806 E019 0.5149111 0.022719041 0.64961426 0.76083839 2 241967718 241967797 80 + 0.125 0.214 0.934
ENSG00000233806 E020 0.2965864 0.036312793 0.24124878   2 241967798 241967848 51 + 0.000 0.213 11.704
ENSG00000233806 E021 0.8200183 0.018409531 0.53887340 0.67023345 2 241967849 241968244 396 + 0.301 0.214 -0.652
ENSG00000233806 E022 0.0000000       2 241968245 241968246 2 +      
ENSG00000233806 E023 0.9557277 0.016084549 0.05981787 0.12630337 2 241968247 241968419 173 + 0.426 0.120 -2.387
ENSG00000233806 E024 0.0000000       2 241987698 241988694 997 +      
ENSG00000233806 E025 0.1817044 0.045503715 0.54100057   2 242078460 242078722 263 + 0.000 0.120 10.880