ENSG00000233797

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000430796 ENSG00000233797 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.6374452 1.078318 0.236073 0.4079671 0.03006012 -2.144941 0.037623965 0.042627923 0.09427207 0.042627923 0.05423454 0.9864524 0.13544167 0.080300000 0.3510667 0.2707667 0.38001332 0.03074546   FALSE
ENST00000656359 ENSG00000233797 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.6374452 1.078318 0.236073 0.4079671 0.03006012 -2.144941 0.007576838 0.003157931 0.03773641 0.003157931 0.02052187 1.8591572 0.03302083 0.005933333 0.1436000 0.1376667 0.03074546 0.03074546   FALSE
ENST00000685557 ENSG00000233797 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.6374452 1.078318 0.236073 0.4079671 0.03006012 -2.144941 0.073582422 0.320778612 0.00000000 0.320778612 0.00000000 -5.0477940 0.04317500 0.171000000 0.0000000 -0.1710000 0.93992165 0.03074546   FALSE
ENST00000685832 ENSG00000233797 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.6374452 1.078318 0.236073 0.4079671 0.03006012 -2.144941 0.153813594 0.000000000 0.00000000 0.000000000 0.00000000 0.0000000 0.16649167 0.000000000 0.0000000 0.0000000   0.03074546   FALSE
ENST00000686709 ENSG00000233797 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.6374452 1.078318 0.236073 0.4079671 0.03006012 -2.144941 0.174850752 0.446316393 0.00000000 0.225012626 0.00000000 -5.5119626 0.14040000 0.377200000 0.0000000 -0.3772000 0.35699975 0.03074546   FALSE
ENST00000690214 ENSG00000233797 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.6374452 1.078318 0.236073 0.4079671 0.03006012 -2.144941 0.181470677 0.265436984 0.10406457 0.064148333 0.03874680 -1.2718716 0.47182917 0.365533333 0.5053000 0.1397667 0.87176820 0.03074546   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000233797 E001 0.0000000       6 96199840 96202423 2584 -      
ENSG00000233797 E002 0.0000000       6 96202424 96203015 592 -      
ENSG00000233797 E003 0.0000000       6 96358374 96358430 57 -      
ENSG00000233797 E004 0.0000000       6 96361470 96361587 118 -      
ENSG00000233797 E005 0.1472490 0.050018617 0.318731936   6 96364771 96364807 37 - 0.178 0.000 -11.784
ENSG00000233797 E006 0.2987644 0.032320264 0.102308051   6 96369381 96369480 100 - 0.303 0.000 -14.190
ENSG00000233797 E007 1.0403201 0.027312458 0.009246029 0.02690019 6 96388342 96390977 2636 - 0.605 0.083 -3.856
ENSG00000233797 E008 0.1472490 0.050018617 0.318731936   6 96398909 96398914 6 - 0.178 0.000 -13.455
ENSG00000233797 E009 0.5932625 0.033248579 0.011170829 0.03157637 6 96398915 96399034 120 - 0.480 0.000 -14.875
ENSG00000233797 E010 0.2987644 0.032320264 0.102308051   6 96460440 96460485 46 - 0.303 0.000 -14.190
ENSG00000233797 E011 0.0000000       6 96460486 96460612 127 -      
ENSG00000233797 E012 0.0000000       6 96460613 96460613 1 -      
ENSG00000233797 E013 0.8888167 0.018730650 0.556497374 0.68512765 6 96519295 96519375 81 - 0.401 0.211 -1.274
ENSG00000233797 E014 3.2000196 0.010864776 0.075418762 0.15219116 6 96520669 96521274 606 - 0.480 0.617 0.636
ENSG00000233797 E015 0.2966881 0.032998137 0.102166473   6 96521275 96521281 7 - 0.303 0.000 -14.189
ENSG00000233797 E016 0.5181333 0.023889378 0.327074263 0.47051634 6 96521282 96521284 3 - 0.303 0.083 -2.266
ENSG00000233797 E017 2.6216817 0.010266553 0.035578782 0.08276798 6 96521285 96521403 119 - 0.303 0.547 1.320
ENSG00000233797 E018 3.3569066 0.007551445 0.077183401 0.15498117 6 96521404 96521640 237 - 0.480 0.618 0.639
ENSG00000233797 E019 2.7928046 0.015378759 0.218709192 0.34886627 6 96521641 96521717 77 - 0.480 0.546 0.319