ENSG00000233705

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000449741 ENSG00000233705 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.3708734 0.4082607 0.4297031 0.1250467 0.0514618 0.07212733 0.004009609 0.00000000 0.03207687 0.00000000 0.03207687 2.073027477 0.00836250 0.0000000 0.0669000 0.06690000 0.80267614 0.0394271   FALSE
ENST00000587899 ENSG00000233705 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.3708734 0.4082607 0.4297031 0.1250467 0.0514618 0.07212733 0.063558759 0.18965070 0.00000000 0.09544764 0.00000000 -4.319406212 0.14042917 0.3554000 0.0000000 -0.35540000 0.03942710 0.0394271   FALSE
ENST00000630476 ENSG00000233705 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.3708734 0.4082607 0.4297031 0.1250467 0.0514618 0.07212733 0.038826024 0.06462419 0.06509647 0.03437775 0.03325972 0.009101827 0.09322083 0.1217667 0.1636333 0.04186667 1.00000000 0.0394271   FALSE
ENST00000668981 ENSG00000233705 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.3708734 0.4082607 0.4297031 0.1250467 0.0514618 0.07212733 0.191861115 0.09668173 0.24927378 0.03965082 0.02475907 1.281163170 0.54797917 0.2200667 0.5863000 0.36623333 0.06266047 0.0394271 FALSE FALSE
ENST00000690082 ENSG00000233705 HEK293_OSMI2_2hA HEK293_TMG_2hB   lncRNA lncRNA 0.3708734 0.4082607 0.4297031 0.1250467 0.0514618 0.07212733 0.024543783 0.02757951 0.04085791 0.02757951 0.04085791 0.436526075 0.07210000 0.1740333 0.0846000 -0.08943333 1.00000000 0.0394271   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000233705 E001 0.2903454 0.695505410 0.35316786   7 107650260 107652180 1921 - 0.220 0.000 -11.733
ENSG00000233705 E002 0.0000000       7 107653968 107653971 4 -      
ENSG00000233705 E003 0.0000000       7 107653972 107653975 4 -      
ENSG00000233705 E004 0.4031496 0.039018219 0.21479275 0.34419565 7 107653976 107654050 75 - 0.000 0.215 13.120
ENSG00000233705 E005 1.1018414 0.133123118 0.10500801 0.19810644 7 107654051 107654233 183 - 0.124 0.418 2.287
ENSG00000233705 E006 0.0000000       7 107654611 107654643 33 -      
ENSG00000233705 E007 0.0000000       7 107654644 107654816 173 -      
ENSG00000233705 E008 0.0000000       7 107655096 107655312 217 -      
ENSG00000233705 E009 0.0000000       7 107656122 107656234 113 -      
ENSG00000233705 E010 0.0000000       7 107656235 107656845 611 -      
ENSG00000233705 E011 1.9196736 0.009868827 0.01613788 0.04303654 7 107656846 107659613 2768 - 0.635 0.292 -1.793
ENSG00000233705 E012 0.7425998 0.019315398 0.54838290 0.67824054 7 107659614 107659751 138 - 0.300 0.214 -0.642
ENSG00000233705 E013 2.5160791 0.007121013 0.76847453 0.85039074 7 107659752 107660206 455 - 0.521 0.588 0.307
ENSG00000233705 E014 0.4417591 0.027744239 0.64158894 0.75457642 7 107660207 107661300 1094 - 0.124 0.214 0.942
ENSG00000233705 E015 0.1515154 0.052926590 0.46952612   7 107661301 107661601 301 - 0.124 0.000 -13.009
ENSG00000233705 E016 2.1735084 0.012615702 0.48332896 0.62134561 7 107661602 107661758 157 - 0.424 0.551 0.625
ENSG00000233705 E017 0.4470576 0.024309329 0.50730344 0.64288275 7 107661759 107661822 64 - 0.221 0.120 -1.056
ENSG00000233705 E018 0.0000000       7 107661823 107661832 10 -      
ENSG00000233705 E019 0.0000000       7 107661833 107661838 6 -      
ENSG00000233705 E020 0.0000000       7 107661839 107661858 20 -      
ENSG00000233705 E021 0.0000000       7 107661859 107662023 165 -      
ENSG00000233705 E022 0.1482932 0.047055551 0.51119998   7 107662024 107662064 41 - 0.000 0.120 12.201
ENSG00000233705 E023 0.1482932 0.047055551 0.51119998   7 107662065 107662065 1 - 0.000 0.120 12.201
ENSG00000233705 E024 0.1482932 0.047055551 0.51119998   7 107662066 107662100 35 - 0.000 0.120 12.201
ENSG00000233705 E025 0.1482932 0.047055551 0.51119998   7 107662101 107662151 51 - 0.000 0.120 12.201
ENSG00000233705 E026 0.0000000       7 107662152 107662161 10 -      
ENSG00000233705 E027 0.0000000       7 107662162 107662204 43 -