ENSG00000233184

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000451213 ENSG00000233184 HEK293_OSMI2_2hA HEK293_TMG_2hB lncRNA retained_intron 3.184885 2.005587 5.165614 0.2118476 0.2458254 1.36053 0.2370852 0.1769715 0.45477638 0.01079762 0.03184935 1.3137185 0.07613333 0.08940000 0.08903333 -0.0003666667 1.0000000000 0.0003131867   FALSE
ENST00000453011 ENSG00000233184 HEK293_OSMI2_2hA HEK293_TMG_2hB lncRNA lncRNA 3.184885 2.005587 5.165614 0.2118476 0.2458254 1.36053 0.8913567 0.2621949 2.24896861 0.15446928 0.10590728 3.0529521 0.23765833 0.14173333 0.43543333 0.2937000000 0.2404641393 0.0003131867   FALSE
ENST00000454721 ENSG00000233184 HEK293_OSMI2_2hA HEK293_TMG_2hB lncRNA lncRNA 3.184885 2.005587 5.165614 0.2118476 0.2458254 1.36053 0.1487574 0.1578723 0.09550603 0.10529924 0.07500524 -0.6700384 0.04931250 0.07286667 0.01743333 -0.0554333333 0.5030479390 0.0003131867   FALSE
ENST00000654574 ENSG00000233184 HEK293_OSMI2_2hA HEK293_TMG_2hB lncRNA lncRNA 3.184885 2.005587 5.165614 0.2118476 0.2458254 1.36053 0.3908167 0.4982305 0.38309160 0.11622496 0.01548163 -0.3706174 0.13955000 0.24356667 0.07423333 -0.1693333333 0.0003131867 0.0003131867   FALSE
ENST00000656047 ENSG00000233184 HEK293_OSMI2_2hA HEK293_TMG_2hB lncRNA lncRNA 3.184885 2.005587 5.165614 0.2118476 0.2458254 1.36053 0.6842095 0.4501746 0.93682395 0.05795751 0.12804811 1.0409150 0.21251667 0.22343333 0.18066667 -0.0427666667 0.6469316723 0.0003131867   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000233184 E001 0.0000000       1 101025844 101025845 2 +      
ENSG00000233184 E002 0.0000000       1 101025846 101025849 4 +      
ENSG00000233184 E003 0.0000000       1 101025850 101025853 4 +      
ENSG00000233184 E004 0.0000000       1 101025854 101025854 1 +      
ENSG00000233184 E005 0.1817044 0.0460042572 3.211653e-01   1 101025855 101025856 2 + 0.000 0.145 8.682
ENSG00000233184 E006 2.9944716 0.0051853424 2.756145e-01 4.149496e-01 1 101025857 101025868 12 + 0.532 0.696 0.722
ENSG00000233184 E007 4.1672909 0.0038967688 4.035286e-01 5.473030e-01 1 101025869 101025877 9 + 0.675 0.789 0.463
ENSG00000233184 E008 4.3155841 0.0040190851 2.982169e-01 4.396428e-01 1 101025878 101025886 9 + 0.675 0.816 0.569
ENSG00000233184 E009 4.9787884 0.0038245570 1.444895e-01 2.541276e-01 1 101025887 101025889 3 + 0.699 0.888 0.750
ENSG00000233184 E010 12.4129980 0.0014846336 2.624952e-02 6.445168e-02 1 101025890 101025906 17 + 1.036 1.237 0.718
ENSG00000233184 E011 12.8516366 0.0014368460 3.255685e-02 7.691577e-02 1 101025907 101025909 3 + 1.057 1.247 0.677
ENSG00000233184 E012 29.9314661 0.0011063949 2.136781e-01 3.428676e-01 1 101025910 101025947 38 + 1.467 1.540 0.251
ENSG00000233184 E013 26.3584819 0.0012261160 3.717395e-01 5.162114e-01 1 101025948 101025950 3 + 1.421 1.476 0.190
ENSG00000233184 E014 52.5077376 0.0004759081 9.016525e-02 1.753751e-01 1 101025951 101026036 86 + 1.702 1.776 0.248
ENSG00000233184 E015 42.3341545 0.0005836476 4.906079e-01 6.279589e-01 1 101026037 101026061 25 + 1.630 1.661 0.105
ENSG00000233184 E016 2.6572895 0.0580996127 4.489792e-01 5.901830e-01 1 101026062 101027130 1069 + 0.623 0.474 -0.693
ENSG00000233184 E017 0.0000000       1 101063601 101063610 10 +      
ENSG00000233184 E018 0.0000000       1 101063611 101063639 29 +      
ENSG00000233184 E019 14.5957224 0.0015277458 1.352940e-03 5.152591e-03 1 101072660 101072830 171 + 1.306 1.005 -1.075
ENSG00000233184 E020 10.5831706 0.0095206171 1.070128e-06 8.825201e-06 1 101075276 101075380 105 + 1.244 0.621 -2.382
ENSG00000233184 E021 3.7739865 0.0041590709 3.263691e-04 1.486325e-03 1 101075381 101075394 14 + 0.854 0.254 -2.952
ENSG00000233184 E022 19.4133123 0.0040996596 3.952570e-01 5.390753e-01 1 101075395 101075493 99 + 1.344 1.266 -0.273
ENSG00000233184 E023 32.8346508 0.0066817063 1.248871e-01 2.269669e-01 1 101075494 101075716 223 + 1.578 1.458 -0.410
ENSG00000233184 E024 35.7918662 0.0013357580 1.145766e-03 4.456731e-03 1 101077363 101077508 146 + 1.643 1.441 -0.693
ENSG00000233184 E025 10.4952972 0.0020659267 1.096105e-01 2.049971e-01 1 101080389 101080613 225 + 1.123 0.951 -0.629
ENSG00000233184 E026 4.1781682 0.0041910178 9.970991e-04 3.948030e-03 1 101080614 101080886 273 + 0.870 0.341 -2.427
ENSG00000233184 E027 4.7620031 0.1358602303 2.259623e-01 3.575468e-01 1 101080887 101080998 112 + 0.854 0.584 -1.115
ENSG00000233184 E028 39.1919237 0.0009495220 3.729232e-05 2.165423e-04 1 101080999 101083460 2462 + 1.695 1.453 -0.828
ENSG00000233184 E029 30.5810997 0.0007869165 7.150347e-01 8.110802e-01 1 101083461 101083574 114 + 1.501 1.520 0.064
ENSG00000233184 E030 2.0346679 0.0072111782 9.094350e-01 9.464751e-01 1 101085052 101085157 106 + 0.496 0.475 -0.107
ENSG00000233184 E031 9.0372660 0.0137798653 9.701081e-01 9.853000e-01 1 101085158 101085987 830 + 1.004 1.004 0.002
ENSG00000233184 E032 121.2684250 0.0003079444 2.895960e-08 3.269358e-07 1 101086852 101090513 3662 + 2.018 2.171 0.513