ENSG00000230798

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000431294 ENSG00000230798 HEK293_OSMI2_2hA HEK293_TMG_2hB FOXD3-AS1 lncRNA lncRNA 8.893142 15.3595 6.515171 0.6673102 0.1735313 -1.235983 1.9955163 3.3723712 1.7342531 0.24303157 0.04283889 -0.9554257 0.23413750 0.2190333 0.26623333 0.04720000 3.201332e-01 7.834222e-08 TRUE  
ENST00000686286 ENSG00000230798 HEK293_OSMI2_2hA HEK293_TMG_2hB FOXD3-AS1 lncRNA lncRNA 8.893142 15.3595 6.515171 0.6673102 0.1735313 -1.235983 0.4946187 1.2173300 0.2125850 0.19138537 0.21258495 -2.4630952 0.05295417 0.0802000 0.03366667 -0.04653333 2.675916e-01 7.834222e-08    
ENST00000686639 ENSG00000230798 HEK293_OSMI2_2hA HEK293_TMG_2hB FOXD3-AS1 lncRNA lncRNA 8.893142 15.3595 6.515171 0.6673102 0.1735313 -1.235983 0.4213544 0.2797041 0.1960509 0.06783269 0.10023523 -0.4915793 0.06412083 0.0183000 0.03036667 0.01206667 7.261968e-01 7.834222e-08    
ENST00000690333 ENSG00000230798 HEK293_OSMI2_2hA HEK293_TMG_2hB FOXD3-AS1 lncRNA lncRNA 8.893142 15.3595 6.515171 0.6673102 0.1735313 -1.235983 0.2182722 0.0000000 0.6594238 0.00000000 0.25202659 6.0648480 0.02387083 0.0000000 0.09943333 0.09943333 7.834222e-08 7.834222e-08 FALSE  
ENST00000690549 ENSG00000230798 HEK293_OSMI2_2hA HEK293_TMG_2hB FOXD3-AS1 lncRNA lncRNA 8.893142 15.3595 6.515171 0.6673102 0.1735313 -1.235983 4.3555090 8.6428662 2.7453564 0.63436590 0.16188915 -1.6509391 0.45194167 0.5614333 0.42303333 -0.13840000 5.263896e-02 7.834222e-08 FALSE  
MSTRG.1320.9 ENSG00000230798 HEK293_OSMI2_2hA HEK293_TMG_2hB FOXD3-AS1 lncRNA   8.893142 15.3595 6.515171 0.6673102 0.1735313 -1.235983 0.4838549 0.7536312 0.4419703 0.10810594 0.07656509 -0.7566479 0.05300000 0.0493000 0.06756667 0.01826667 6.147901e-01 7.834222e-08 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000230798 E001 0.0000000       1 63320878 63320878 1 -      
ENSG00000230798 E002 0.3697384 0.0274424043 0.63449304 0.74893645 1 63320879 63320883 5 - 0.000 0.145 9.923
ENSG00000230798 E003 0.5180316 0.0209235851 0.37632193 0.52065333 1 63320884 63320885 2 - 0.000 0.203 12.187
ENSG00000230798 E004 106.7493337 0.0003474624 0.59544441 0.71753985 1 63320886 63321190 305 - 1.946 1.966 0.065
ENSG00000230798 E005 1.1028855 0.0120970080 0.10294125 0.19494893 1 63321191 63321362 172 - 0.000 0.341 13.151
ENSG00000230798 E006 1.1028855 0.0120970080 0.10294125 0.19494893 1 63321363 63321366 4 - 0.000 0.341 13.151
ENSG00000230798 E007 108.0036049 0.0003274300 0.32645689 0.46989939 1 63321367 63321463 97 - 1.939 1.973 0.116
ENSG00000230798 E008 2.8032869 0.0056338945 0.84860141 0.90599389 1 63321464 63321583 120 - 0.496 0.530 0.162
ENSG00000230798 E009 1.5479409 0.3123378299 0.96585559 0.98253226 1 63321584 63321590 7 - 0.315 0.356 0.253
ENSG00000230798 E010 1.4769670 0.3125944842 0.24429399 0.37924794 1 63321591 63321624 34 - 0.496 0.267 -1.327
ENSG00000230798 E011 1.6617919 0.0923553021 0.72800998 0.82054287 1 63321625 63321664 40 - 0.415 0.346 -0.396
ENSG00000230798 E012 16.4265329 0.0051441145 0.90489331 0.94345376 1 63321665 63321850 186 - 1.172 1.184 0.042
ENSG00000230798 E013 11.7076168 0.0612835207 0.79550900 0.86940897 1 63321851 63321901 51 - 1.067 1.042 -0.089
ENSG00000230798 E014 10.8157668 0.0277660262 0.90754661 0.94532009 1 63321902 63321944 43 - 1.025 1.011 -0.051
ENSG00000230798 E015 13.0747602 0.0189375100 0.43964102 0.58139338 1 63321945 63322080 136 - 1.156 1.072 -0.302
ENSG00000230798 E016 8.2725800 0.0024092789 0.45850687 0.59881564 1 63322081 63322309 229 - 0.836 0.932 0.364
ENSG00000230798 E017 3.3859904 0.0051294600 0.46474517 0.60446099 1 63322310 63322315 6 - 0.496 0.621 0.576
ENSG00000230798 E018 31.6905447 0.0027619435 0.05750064 0.12233778 1 63322316 63322501 186 - 1.338 1.482 0.497
ENSG00000230798 E019 28.6108254 0.0126452518 0.16741150 0.28483575 1 63323048 63323490 443 - 1.482 1.364 -0.407
ENSG00000230798 E020 75.6114365 0.0004702776 0.03041285 0.07277075 1 63323491 63324354 864 - 1.879 1.791 -0.295
ENSG00000230798 E021 0.0000000       1 63324355 63325101 747 -