ENSG00000205771

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000381680 ENSG00000205771 HEK293_OSMI2_2hA HEK293_TMG_2hB CATSPER2P1 transcribed_unprocessed_pseudogene processed_transcript 1.323782 1.921815 1.51172 0.1134467 0.3556016 -0.3442545 0.04587056 0.03487107 0.00000000 0.03487107 0.00000000 -2.1657857 0.07122083 0.01633333 0.00000000 -0.01633333 0.7176450942 0.0002867227   FALSE
ENST00000416302 ENSG00000205771 HEK293_OSMI2_2hA HEK293_TMG_2hB CATSPER2P1 transcribed_unprocessed_pseudogene processed_transcript 1.323782 1.921815 1.51172 0.1134467 0.3556016 -0.3442545 0.10305248 0.00000000 0.00000000 0.00000000 0.00000000 0.0000000 0.06829167 0.00000000 0.00000000 0.00000000   0.0002867227 TRUE FALSE
ENST00000429276 ENSG00000205771 HEK293_OSMI2_2hA HEK293_TMG_2hB CATSPER2P1 transcribed_unprocessed_pseudogene processed_transcript 1.323782 1.921815 1.51172 0.1134467 0.3556016 -0.3442545 0.07755801 0.05525591 0.10354243 0.01048746 0.03031693 0.7990509 0.06725833 0.02873333 0.08146667 0.05273333 0.3645576006 0.0002867227   FALSE
ENST00000446479 ENSG00000205771 HEK293_OSMI2_2hA HEK293_TMG_2hB CATSPER2P1 transcribed_unprocessed_pseudogene processed_transcript 1.323782 1.921815 1.51172 0.1134467 0.3556016 -0.3442545 0.06905309 0.00000000 0.11638034 0.00000000 0.11638034 3.6597002 0.04577500 0.00000000 0.05260000 0.05260000 0.6969414112 0.0002867227   FALSE
ENST00000687891 ENSG00000205771 HEK293_OSMI2_2hA HEK293_TMG_2hB CATSPER2P1 transcribed_unprocessed_pseudogene processed_transcript 1.323782 1.921815 1.51172 0.1134467 0.3556016 -0.3442545 0.06382588 0.00000000 0.06973255 0.00000000 0.06973255 2.9951689 0.06290833 0.00000000 0.05520000 0.05520000 0.7624454554 0.0002867227   FALSE
ENST00000687921 ENSG00000205771 HEK293_OSMI2_2hA HEK293_TMG_2hB CATSPER2P1 transcribed_unprocessed_pseudogene processed_transcript 1.323782 1.921815 1.51172 0.1134467 0.3556016 -0.3442545 0.14580390 0.36839578 0.00000000 0.23726472 0.00000000 -5.2418241 0.10874167 0.18280000 0.00000000 -0.18280000 0.2044183089 0.0002867227   FALSE
ENST00000687929 ENSG00000205771 HEK293_OSMI2_2hA HEK293_TMG_2hB CATSPER2P1 transcribed_unprocessed_pseudogene processed_transcript 1.323782 1.921815 1.51172 0.1134467 0.3556016 -0.3442545 0.16763348 0.40847358 0.07705180 0.27108375 0.07705180 -2.2651905 0.12007500 0.22330000 0.07276667 -0.15053333 0.6390308477 0.0002867227 FALSE FALSE
ENST00000689243 ENSG00000205771 HEK293_OSMI2_2hA HEK293_TMG_2hB CATSPER2P1 transcribed_unprocessed_pseudogene processed_transcript 1.323782 1.921815 1.51172 0.1134467 0.3556016 -0.3442545 0.13189015 0.00000000 0.52234089 0.00000000 0.31682357 5.7342785 0.08350000 0.00000000 0.29693333 0.29693333 0.0002867227 0.0002867227   FALSE
ENST00000689686 ENSG00000205771 HEK293_OSMI2_2hA HEK293_TMG_2hB CATSPER2P1 transcribed_unprocessed_pseudogene processed_transcript 1.323782 1.921815 1.51172 0.1134467 0.3556016 -0.3442545 0.22473352 0.40418782 0.00000000 0.20528241 0.00000000 -5.3722132 0.14386667 0.20323333 0.00000000 -0.20323333 0.1544721340 0.0002867227 FALSE FALSE
ENST00000691160 ENSG00000205771 HEK293_OSMI2_2hA HEK293_TMG_2hB CATSPER2P1 transcribed_unprocessed_pseudogene processed_transcript 1.323782 1.921815 1.51172 0.1134467 0.3556016 -0.3442545 0.20554463 0.19416578 0.55410287 0.09884965 0.08116955 1.4662172 0.15809167 0.10666667 0.38673333 0.28006667 0.1627064834 0.0002867227   FALSE
ENST00000692045 ENSG00000205771 HEK293_OSMI2_2hA HEK293_TMG_2hB CATSPER2P1 transcribed_unprocessed_pseudogene processed_transcript 1.323782 1.921815 1.51172 0.1134467 0.3556016 -0.3442545 0.07596795 0.44670000 0.06856865 0.17263213 0.06856865 -2.5392212 0.05462500 0.23376667 0.05426667 -0.17950000 0.2153194969 0.0002867227 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000205771 E001 0.3030308 0.068338765 0.16163704   15 43726918 43727180 263 - 0.235 0.000 -11.483
ENSG00000205771 E002 0.0000000       15 43727181 43727212 32 -      
ENSG00000205771 E003 0.0000000       15 43728666 43728830 165 -      
ENSG00000205771 E004 0.1817044 0.047026137 0.59402374   15 43729183 43729392 210 - 0.000 0.113 11.728
ENSG00000205771 E005 0.0000000       15 43731817 43731874 58 -      
ENSG00000205771 E006 0.0000000       15 43732203 43732302 100 -      
ENSG00000205771 E007 0.1451727 0.048873023 0.39796782   15 43732517 43732695 179 - 0.133 0.000 -13.069
ENSG00000205771 E008 0.2965864 0.053995680 0.28436841   15 43735430 43735548 119 - 0.000 0.201 12.555
ENSG00000205771 E009 0.0000000       15 43735934 43736154 221 -      
ENSG00000205771 E010 0.0000000       15 43736155 43736310 156 -      
ENSG00000205771 E011 0.1482932 0.041649680 0.59833930   15 43736311 43736511 201 - 0.000 0.112 11.729
ENSG00000205771 E012 0.3299976 0.027442404 0.27108521   15 43736512 43736728 217 - 0.000 0.202 12.579
ENSG00000205771 E013 0.3332198 0.029027899 0.87647772   15 43736729 43736835 107 - 0.133 0.113 -0.276
ENSG00000205771 E014 4.2088868 0.100627167 0.07253346 0.14756810 15 43736836 43737008 173 - 0.894 0.524 -1.546
ENSG00000205771 E015 1.0339748 0.217892276 0.66734250 0.77462518 15 43743813 43744150 338 - 0.234 0.340 0.732
ENSG00000205771 E016 0.3697384 0.025512071 0.27062291 0.40925578 15 43744151 43744198 48 - 0.000 0.202 12.582
ENSG00000205771 E017 0.3697384 0.025512071 0.27062291 0.40925578 15 43744199 43744200 2 - 0.000 0.202 12.582
ENSG00000205771 E018 0.3697384 0.025512071 0.27062291 0.40925578 15 43744201 43744203 3 - 0.000 0.202 12.582
ENSG00000205771 E019 0.3697384 0.025512071 0.27062291 0.40925578 15 43744204 43744219 16 - 0.000 0.202 12.582
ENSG00000205771 E020 0.3697384 0.025512071 0.27062291 0.40925578 15 43744220 43744247 28 - 0.000 0.202 12.582
ENSG00000205771 E021 3.3902448 0.006014147 0.17865854 0.29946934 15 43744248 43744394 147 - 0.498 0.711 0.946
ENSG00000205771 E022 16.3638086 0.001422584 0.23581425 0.36934342 15 43744395 43744568 174 - 1.175 1.273 0.345
ENSG00000205771 E023 15.2565037 0.001595078 0.58889309 0.71203251 15 43745022 43745167 146 - 1.175 1.229 0.192
ENSG00000205771 E024 2.4744523 0.006900340 0.04744689 0.10463136 15 43745168 43745170 3 - 0.694 0.394 -1.414
ENSG00000205771 E025 6.3620811 0.003132529 0.08077707 0.16075565 15 43746048 43746213 166 - 0.966 0.780 -0.713
ENSG00000205771 E026 1.8735980 0.008133366 0.06589614 0.13653374 15 43746214 43746321 108 - 0.235 0.564 1.893
ENSG00000205771 E027 1.0759214 0.012565559 0.02400362 0.05981786 15 43746531 43747094 564 - 0.498 0.113 -2.861