ENSG00000205763

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000381639 ENSG00000205763 HEK293_OSMI2_2hA HEK293_TMG_2hB RP9P transcribed_unprocessed_pseudogene processed_transcript 3.770148 4.764532 4.086397 0.7088633 0.3510542 -0.2210038 0.5437093 0.3626000 0.9304108 0.1546381 0.1479117 1.3356634 0.1494000 0.0917000 0.2331667 0.1414667 0.191026866 0.002336323 TRUE FALSE
ENST00000685019 ENSG00000205763 HEK293_OSMI2_2hA HEK293_TMG_2hB RP9P transcribed_unprocessed_pseudogene processed_transcript 3.770148 4.764532 4.086397 0.7088633 0.3510542 -0.2210038 0.4922382 0.7074135 0.2171525 0.4197004 0.2171525 -1.6591437 0.1280208 0.1833000 0.0496000 -0.1337000 0.600265074 0.002336323   FALSE
MSTRG.29682.1 ENSG00000205763 HEK293_OSMI2_2hA HEK293_TMG_2hB RP9P transcribed_unprocessed_pseudogene   3.770148 4.764532 4.086397 0.7088633 0.3510542 -0.2210038 0.8952034 1.7934198 0.5949233 0.9552512 0.4537725 -1.5759110 0.2271958 0.3261333 0.1330000 -0.1931333 0.771544984 0.002336323   FALSE
MSTRG.29682.2 ENSG00000205763 HEK293_OSMI2_2hA HEK293_TMG_2hB RP9P transcribed_unprocessed_pseudogene   3.770148 4.764532 4.086397 0.7088633 0.3510542 -0.2210038 0.7213857 1.0115963 0.7689629 0.5010915 0.1842303 -0.3911988 0.1978167 0.2159000 0.1986000 -0.0173000 1.000000000 0.002336323   FALSE
MSTRG.29682.6 ENSG00000205763 HEK293_OSMI2_2hA HEK293_TMG_2hB RP9P transcribed_unprocessed_pseudogene   3.770148 4.764532 4.086397 0.7088633 0.3510542 -0.2210038 1.0812370 0.8543802 1.4760775 0.1773221 0.2024773 0.7817714 0.2877667 0.1763000 0.3590333 0.1827333 0.002336323 0.002336323 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000205763 E001 1.834048 0.020850402 0.674563162 0.780049609 7 32916789 32916814 26 - 0.482 0.409 -0.380
ENSG00000205763 E002 7.804149 0.002565838 0.890490134 0.934050253 7 32916815 32916857 43 - 0.928 0.945 0.065
ENSG00000205763 E003 80.742923 0.001516763 0.001322983 0.005053229 7 32916858 32917542 685 - 1.848 1.952 0.348
ENSG00000205763 E004 21.318623 0.001302235 0.867414570 0.918742770 7 32918311 32918372 62 - 1.356 1.347 -0.034
ENSG00000205763 E005 25.043123 0.001611228 0.751541183 0.837961491 7 32921339 32921430 92 - 1.428 1.409 -0.065
ENSG00000205763 E006 0.810555 0.014231444 0.142627634 0.251619181 7 32928562 32928691 130 - 0.372 0.118 -2.118
ENSG00000205763 E007 12.608107 0.017220771 0.129772410 0.233842144 7 32930078 32930108 31 - 1.220 1.053 -0.600
ENSG00000205763 E008 1.069477 0.012144442 0.621977234 0.738858784 7 32933400 32933483 84 - 0.372 0.287 -0.537
ENSG00000205763 E009 7.942302 0.014354929 0.425805485 0.568698249 7 32933814 32933896 83 - 0.992 0.897 -0.357
ENSG00000205763 E010 7.021214 0.084645361 0.479338554 0.617720592 7 32942320 32942551 232 - 0.809 0.941 0.506
ENSG00000205763 E011 13.855142 0.001516763 0.001022569 0.004036729 7 32942870 32943199 330 - 1.308 1.028 -1.000