ENSG00000204560

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-3 / 3
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000376437	ENSG00000204560	HEK293_OSMI2_2hA	HEK293_TMG_2hB	DHX16	protein_coding	protein_coding	47.50739	65.88153	37.29547	0.5280931	0.7786735	-0.8207058	4.046684	10.3092	0.6002943	3.578089	0.2303979	-4.0796828	0.07597500	0.1565	0.01623333	-0.14026667	3.922894e-03	5.03684e-42	FALSE	TRUE
ENST00000376442	ENSG00000204560	HEK293_OSMI2_2hA	HEK293_TMG_2hB	DHX16	protein_coding	protein_coding	47.50739	65.88153	37.29547	0.5280931	0.7786735	-0.8207058	39.545431	52.4777	31.3503293	3.379334	1.3320288	-0.7430386	0.83085833	0.7966	0.83980000	0.04320000	7.948210e-01	5.03684e-42	FALSE	TRUE
ENST00000415603	ENSG00000204560	HEK293_OSMI2_2hA	HEK293_TMG_2hB	DHX16	protein_coding	protein_coding	47.50739	65.88153	37.29547	0.5280931	0.7786735	-0.8207058	1.535570	0.0000	2.9794932	0.000000	0.2627358	8.2237571	0.04082083	0.0000	0.07973333	0.07973333	5.036840e-42	5.03684e-42	FALSE	FALSE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 31
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groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000204560	E001	3.022582	0.0052594181	3.650139e-01	5.093530e-01	6	30653119	30653126	8	-	0.460	0.617	0.735
ENSG00000204560	E002	187.212199	0.0027056104	6.616240e-05	3.615828e-04	6	30653127	30653248	122	-	2.110	2.271	0.540
ENSG00000204560	E003	298.616214	0.0004906432	1.041448e-08	1.279171e-07	6	30653249	30653289	41	-	2.319	2.470	0.503
ENSG00000204560	E004	402.546047	0.0027531765	4.753901e-07	4.223072e-06	6	30653290	30653370	81	-	2.433	2.603	0.569
ENSG00000204560	E005	718.731089	0.0033094700	2.503285e-05	1.517519e-04	6	30654706	30654879	174	-	2.709	2.847	0.458
ENSG00000204560	E006	315.525237	0.0033021673	3.805804e-03	1.259693e-02	6	30655175	30655183	9	-	2.374	2.485	0.369
ENSG00000204560	E007	576.348196	0.0026632660	9.167716e-05	4.828861e-04	6	30655184	30655336	153	-	2.626	2.747	0.405
ENSG00000204560	E008	534.913203	0.0006910350	4.725353e-07	4.200117e-06	6	30655435	30655597	163	-	2.601	2.713	0.371
ENSG00000204560	E009	360.506702	0.0002628165	1.331406e-03	5.080690e-03	6	30656198	30656265	68	-	2.458	2.532	0.249
ENSG00000204560	E010	461.603763	0.0027449095	9.640173e-02	1.849626e-01	6	30656391	30656509	119	-	2.577	2.635	0.192
ENSG00000204560	E011	543.795629	0.0001190692	4.571318e-03	1.474074e-02	6	30656597	30656759	163	-	2.651	2.704	0.177
ENSG00000204560	E012	492.251764	0.0003195416	5.905584e-01	7.133945e-01	6	30656952	30657092	141	-	2.650	2.644	-0.017
ENSG00000204560	E013	228.689493	0.0038340695	1.918698e-02	4.974294e-02	6	30659472	30659472	1	-	2.373	2.289	-0.280
ENSG00000204560	E014	503.368334	0.0010671520	7.219266e-02	1.469884e-01	6	30659473	30659624	152	-	2.680	2.645	-0.118
ENSG00000204560	E015	1.540381	0.0318234580	2.598633e-01	3.973296e-01	6	30659724	30659735	12	-	0.526	0.326	-1.077
ENSG00000204560	E016	355.683193	0.0003586426	9.598082e-01	9.787269e-01	6	30659736	30659834	99	-	2.500	2.506	0.018
ENSG00000204560	E017	576.223287	0.0001826230	8.847938e-03	2.590190e-02	6	30660032	30660242	211	-	2.741	2.702	-0.129
ENSG00000204560	E018	6.166849	0.0027234661	6.317884e-06	4.396181e-05	6	30660243	30660577	335	-	1.123	0.568	-2.186
ENSG00000204560	E019	4.303197	0.0159791320	4.386911e-01	5.805627e-01	6	30661756	30661983	228	-	0.757	0.642	-0.480
ENSG00000204560	E020	383.391581	0.0007013795	8.032513e-04	3.270721e-03	6	30662627	30662742	116	-	2.587	2.516	-0.238
ENSG00000204560	E021	304.448292	0.0001750992	7.914066e-06	5.381150e-05	6	30662911	30663021	111	-	2.504	2.411	-0.310
ENSG00000204560	E022	394.293244	0.0001807032	1.612751e-04	7.974812e-04	6	30664801	30664992	192	-	2.598	2.528	-0.231
ENSG00000204560	E023	225.870343	0.0002062210	1.390816e-01	2.468114e-01	6	30665071	30665129	59	-	2.333	2.299	-0.113
ENSG00000204560	E024	369.525912	0.0066099975	6.860047e-01	7.885871e-01	6	30665130	30665274	145	-	2.533	2.518	-0.051
ENSG00000204560	E025	602.572052	0.0034800347	9.441738e-02	1.820069e-01	6	30665479	30665733	255	-	2.768	2.721	-0.159
ENSG00000204560	E026	287.968478	0.0019743583	3.243673e-03	1.098349e-02	6	30670410	30670466	57	-	2.474	2.389	-0.284
ENSG00000204560	E027	506.003075	0.0009051300	9.404127e-08	9.597499e-07	6	30670790	30670952	163	-	2.734	2.624	-0.365
ENSG00000204560	E028	509.561458	0.0009501872	7.886276e-13	1.969978e-11	6	30671036	30671274	239	-	2.762	2.613	-0.498
ENSG00000204560	E029	367.352633	0.0082967722	4.242494e-02	9.549203e-02	6	30672635	30672955	321	-	2.583	2.492	-0.302
ENSG00000204560	E030	119.689927	0.0151209516	1.873384e-01	3.103934e-01	6	30672956	30673085	130	-	2.092	2.009	-0.276
ENSG00000204560	E031	1.314870	0.0504914233	1.013928e-01	1.925845e-01	6	30673086	30673189	104	-	0.526	0.224	-1.800

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000204560

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3