ENSG00000196792

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000355683 ENSG00000196792 HEK293_OSMI2_2hA HEK293_TMG_2hB STRN3 protein_coding protein_coding 9.26981 3.17248 15.5276 0.2222711 0.4727555 2.28754 5.0689856 2.05276999 7.807553 0.14343991 0.4970149 1.922134 0.6009167 0.647733333 0.5020000 -0.1457333 2.373934e-02 2.420806e-09 FALSE TRUE
ENST00000357479 ENSG00000196792 HEK293_OSMI2_2hA HEK293_TMG_2hB STRN3 protein_coding protein_coding 9.26981 3.17248 15.5276 0.2222711 0.4727555 2.28754 1.0811924 0.84196387 2.242708 0.22657999 0.1769106 1.402796 0.1529667 0.272933333 0.1449667 -0.1279667 3.770908e-01 2.420806e-09 FALSE TRUE
MSTRG.9318.3 ENSG00000196792 HEK293_OSMI2_2hA HEK293_TMG_2hB STRN3 protein_coding   9.26981 3.17248 15.5276 0.2222711 0.4727555 2.28754 1.4075837 0.01693979 3.254622 0.01693979 0.3485304 6.921033 0.1053708 0.004766667 0.2106667 0.2059000 2.420806e-09 2.420806e-09 FALSE TRUE
MSTRG.9318.4 ENSG00000196792 HEK293_OSMI2_2hA HEK293_TMG_2hB STRN3 protein_coding   9.26981 3.17248 15.5276 0.2222711 0.4727555 2.28754 0.7690911 0.01074429 1.644405 0.01074429 0.2674018 6.317454 0.0525750 0.003866667 0.1054667 0.1016000 2.072505e-06 2.420806e-09 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000196792 E001 0.9285706 0.0142611816 7.026705e-02 1.438065e-01 14 30893799 30893803 5 - 0.153 0.513 2.422
ENSG00000196792 E002 280.5805959 0.0033133685 4.701011e-41 1.732670e-38 14 30893804 30895344 1541 - 2.218 2.663 1.485
ENSG00000196792 E003 98.1140858 0.0039175084 4.813795e-01 6.196057e-01 14 30895345 30895580 236 - 1.873 1.956 0.281
ENSG00000196792 E004 57.5345140 0.0050270682 9.461517e-01 9.701958e-01 14 30895662 30895748 87 - 1.654 1.697 0.147
ENSG00000196792 E005 74.0678584 0.0004006261 9.370934e-01 9.644622e-01 14 30902536 30902643 108 - 1.759 1.803 0.148
ENSG00000196792 E006 0.4460135 0.0352035621 7.865424e-01 8.633045e-01 14 30905417 30905417 1 - 0.153 0.000 -8.986
ENSG00000196792 E007 80.9431713 0.0006576219 6.063106e-01 7.264995e-01 14 30905418 30905558 141 - 1.792 1.865 0.247
ENSG00000196792 E008 80.7634538 0.0003760363 7.646462e-02 1.538436e-01 14 30906877 30907044 168 - 1.813 1.771 -0.142
ENSG00000196792 E009 56.9290462 0.0004232921 1.226763e-04 6.260784e-04 14 30911041 30911162 122 - 1.688 1.483 -0.700
ENSG00000196792 E010 47.1842166 0.0005556960 3.673833e-04 1.647953e-03 14 30911777 30911824 48 - 1.610 1.400 -0.720
ENSG00000196792 E011 56.2917214 0.0004671637 5.359224e-03 1.690767e-02 14 30912007 30912065 59 - 1.673 1.543 -0.441
ENSG00000196792 E012 69.5255788 0.0061117339 3.605624e-03 1.202639e-02 14 30912066 30912182 117 - 1.765 1.611 -0.521
ENSG00000196792 E013 0.2987644 0.0274535884 1.000000e+00   14 30912183 30912311 129 - 0.108 0.000 -8.401
ENSG00000196792 E014 70.8669092 0.0006389777 1.338522e-02 3.681246e-02 14 30913524 30913657 134 - 1.764 1.672 -0.310
ENSG00000196792 E015 16.8864362 0.0018536177 4.266232e-01 5.694331e-01 14 30918966 30919106 141 - 1.157 1.116 -0.145
ENSG00000196792 E016 22.5959139 0.0008599833 5.795851e-01 7.044569e-01 14 30929201 30929311 111 - 1.268 1.263 -0.017
ENSG00000196792 E017 0.3030308 0.3903752718 1.000000e+00   14 30931941 30932398 458 - 0.108 0.000 -8.408
ENSG00000196792 E018 74.6024669 0.0052494384 6.520700e-02 1.353797e-01 14 30935163 30935304 142 - 1.781 1.707 -0.250
ENSG00000196792 E019 72.3009776 0.0004473665 9.320538e-04 3.726495e-03 14 30936495 30936624 130 - 1.777 1.636 -0.478
ENSG00000196792 E020 36.2437686 0.0005910194 7.489134e-02 1.513542e-01 14 30947090 30947111 22 - 1.478 1.387 -0.314
ENSG00000196792 E021 74.0513518 0.0003342294 9.854959e-05 5.150750e-04 14 30947112 30947263 152 - 1.794 1.620 -0.589
ENSG00000196792 E022 54.1431499 0.0004789504 7.286089e-04 3.001756e-03 14 30950863 30950944 82 - 1.661 1.483 -0.607
ENSG00000196792 E023 50.2884736 0.0004897833 6.308295e-04 2.646634e-03 14 30955620 30955693 74 - 1.629 1.438 -0.655
ENSG00000196792 E024 49.9985672 0.0010807367 5.041050e-04 2.175426e-03 14 30956139 30956242 104 - 1.628 1.426 -0.692
ENSG00000196792 E025 0.0000000       14 30964355 30964509 155 -      
ENSG00000196792 E026 68.0093899 0.0200080371 6.244421e-03 1.925434e-02 14 31025904 31026401 498 - 1.759 1.549 -0.713