ENSG00000196655

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000533632 ENSG00000196655 HEK293_OSMI2_2hA HEK293_TMG_2hB TRAPPC4 protein_coding protein_coding 62.36625 95.01627 44.78597 9.475977 0.6175109 -1.084957 52.31482 84.11251 36.03469 8.17324 0.7033454 -1.222705 0.8279625 0.8857667 0.8048 -0.08096667 0.0004878522 4.739917e-07 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000196655 E001 43.6389440 0.0085718168 5.979378e-01 7.196244e-01 11 119018763 119018765 3 + 1.621 1.576 -0.154
ENSG00000196655 E002 206.1504753 0.0021337500 2.402344e-01 3.743970e-01 11 119018766 119018789 24 + 2.291 2.245 -0.150
ENSG00000196655 E003 262.8894437 0.0028470455 3.529618e-01 4.972223e-01 11 119018790 119018794 5 + 2.342 2.369 0.091
ENSG00000196655 E004 658.4420267 0.0008883219 8.107386e-01 8.799450e-01 11 119018795 119018943 149 + 2.767 2.759 -0.027
ENSG00000196655 E005 495.5553344 0.0001971017 9.273179e-01 9.582370e-01 11 119018944 119018970 27 + 2.642 2.641 -0.003
ENSG00000196655 E006 6.5740747 0.0026528331 7.175008e-04 2.961725e-03 11 119018971 119019142 172 + 1.087 0.676 -1.584
ENSG00000196655 E007 520.5227202 0.0001184637 5.342454e-01 6.663240e-01 11 119019143 119019188 46 + 2.670 2.660 -0.032
ENSG00000196655 E008 451.7630774 0.0001517522 9.134392e-01 9.491460e-01 11 119019189 119019210 22 + 2.599 2.603 0.010
ENSG00000196655 E009 708.1361888 0.0001257679 9.678715e-01 9.839129e-01 11 119019211 119019317 107 + 2.796 2.795 0.000
ENSG00000196655 E010 15.7117346 0.0011122943 2.283369e-06 1.753740e-05 11 119019318 119019391 74 + 1.431 1.032 -1.414
ENSG00000196655 E011 10.4027743 0.0017156563 1.827481e-05 1.143931e-04 11 119019392 119019424 33 + 1.287 0.859 -1.560
ENSG00000196655 E012 28.2363321 0.0006966571 7.899099e-20 4.914485e-18 11 119019425 119020149 725 + 1.764 1.179 -2.016
ENSG00000196655 E013 561.5183831 0.0001352070 2.687229e-01 4.072080e-01 11 119020150 119020204 55 + 2.707 2.689 -0.060
ENSG00000196655 E014 584.2452138 0.0003093254 8.008676e-01 8.730842e-01 11 119020205 119020253 49 + 2.715 2.711 -0.014
ENSG00000196655 E015 12.0049289 0.0015455275 9.654469e-07 8.035014e-06 11 119020254 119020316 63 + 1.350 0.884 -1.687
ENSG00000196655 E016 65.6294288 0.0004123100 1.992893e-17 9.363781e-16 11 119020317 119021759 1443 + 2.013 1.639 -1.260
ENSG00000196655 E017 396.6082383 0.0009077638 2.662886e-01 4.044640e-01 11 119021760 119021767 8 + 2.564 2.538 -0.086
ENSG00000196655 E018 791.1035700 0.0001601587 6.230614e-02 1.305258e-01 11 119021768 119021873 106 + 2.824 2.851 0.092
ENSG00000196655 E019 460.2046263 0.0006723011 6.771078e-01 7.819040e-01 11 119021874 119021886 13 + 2.602 2.609 0.024
ENSG00000196655 E020 37.0393011 0.0210019307 8.632783e-01 9.158214e-01 11 119023010 119023320 311 + 1.539 1.516 -0.081
ENSG00000196655 E021 1127.5149019 0.0001039856 1.001081e-11 2.084772e-10 11 119023321 119024134 814 + 2.935 3.017 0.273
ENSG00000196655 E022 0.6642364 0.0748318619 4.039978e-01 5.477357e-01 11 119024857 119025454 598 + 0.305 0.151 -1.293