ENSG00000196498

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-8 / 8
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000404121	ENSG00000196498	HEK293_OSMI2_2hA	HEK293_TMG_2hB	NCOR2	protein_coding	protein_coding	22.22822	30.8201	14.52993	1.797555	0.630805	-1.08432	5.2852388	11.5617566	0.28452743	0.6444851	0.28452743	-5.2960621	0.20358333	0.37673333	0.019333333	-0.35740000	0.0082368844	6.64336e-05	FALSE	TRUE
ENST00000404621	ENSG00000196498	HEK293_OSMI2_2hA	HEK293_TMG_2hB	NCOR2	protein_coding	protein_coding	22.22822	30.8201	14.52993	1.797555	0.630805	-1.08432	1.3295489	1.0436872	0.90405809	0.4307088	0.40737521	-0.2050889	0.06227083	0.03300000	0.059966667	0.02696667	0.7697707857	6.64336e-05	FALSE	TRUE
ENST00000405201	ENSG00000196498	HEK293_OSMI2_2hA	HEK293_TMG_2hB	NCOR2	protein_coding	protein_coding	22.22822	30.8201	14.52993	1.797555	0.630805	-1.08432	4.5541169	5.8624682	3.79348768	0.7747236	0.35412874	-0.6266441	0.20953333	0.18896667	0.260433333	0.07146667	0.1424492161	6.64336e-05	FALSE	TRUE
ENST00000418829	ENSG00000196498	HEK293_OSMI2_2hA	HEK293_TMG_2hB	NCOR2	protein_coding	protein_coding	22.22822	30.8201	14.52993	1.797555	0.630805	-1.08432	0.8575039	2.2213301	0.06815946	0.2188739	0.06815946	-4.8353398	0.03054583	0.07253333	0.004633333	-0.06790000	0.0075199365	6.64336e-05	FALSE	TRUE
ENST00000443451	ENSG00000196498	HEK293_OSMI2_2hA	HEK293_TMG_2hB	NCOR2	protein_coding	retained_intron	22.22822	30.8201	14.52993	1.797555	0.630805	-1.08432	1.7005047	3.4570119	0.90386311	0.2254956	0.16084563	-1.9236428	0.07003333	0.11260000	0.061900000	-0.05070000	0.0264540326	6.64336e-05	FALSE	TRUE
MSTRG.8277.15	ENSG00000196498	HEK293_OSMI2_2hA	HEK293_TMG_2hB	NCOR2	protein_coding		22.22822	30.8201	14.52993	1.797555	0.630805	-1.08432	0.4478617	0.0000000	0.75677723	0.0000000	0.38938487	6.2607356	0.02642083	0.00000000	0.054400000	0.05440000	0.1232483522	6.64336e-05	FALSE	TRUE
MSTRG.8277.24	ENSG00000196498	HEK293_OSMI2_2hA	HEK293_TMG_2hB	NCOR2	protein_coding		22.22822	30.8201	14.52993	1.797555	0.630805	-1.08432	0.6866556	0.9279917	1.22610078	0.1617036	0.14173776	0.3981494	0.03150417	0.02970000	0.083833333	0.05413333	0.0000664336	6.64336e-05	FALSE	TRUE
MSTRG.8277.4	ENSG00000196498	HEK293_OSMI2_2hA	HEK293_TMG_2hB	NCOR2	protein_coding		22.22822	30.8201	14.52993	1.797555	0.630805	-1.08432	2.0847921	1.4878584	3.13156694	0.5716917	0.58672600	1.0685830	0.10571250	0.04660000	0.219800000	0.17320000	0.0034567776	6.64336e-05	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 94
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featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000196498	E001	3.7484437	0.0042547084	8.941742e-01	9.363490e-01	12	124324415	124324415	1	-	0.614	0.660	0.201
ENSG00000196498	E002	265.9141167	0.0148947552	4.041997e-09	5.355978e-08	12	124324416	124324597	182	-	2.055	2.484	1.435
ENSG00000196498	E003	764.4413068	0.0101317962	5.889329e-12	1.271761e-10	12	124324598	124325379	782	-	2.553	2.935	1.270
ENSG00000196498	E004	14.1458432	0.0072297714	5.283465e-07	4.651624e-06	12	124325380	124325385	6	-	0.564	1.256	2.674
ENSG00000196498	E005	9.6223401	0.0219815743	2.744302e-03	9.504915e-03	12	124325386	124325396	11	-	0.614	1.088	1.854
ENSG00000196498	E006	7.6296083	0.0126178170	1.925307e-02	4.988493e-02	12	124325397	124325398	2	-	0.614	0.982	1.467
ENSG00000196498	E007	10.1591490	0.0017728973	3.336792e-03	1.125394e-02	12	124325399	124325408	10	-	0.699	1.095	1.517
ENSG00000196498	E008	18.3464592	0.0010510032	6.356527e-03	1.954911e-02	12	124325409	124325419	11	-	1.033	1.318	1.017
ENSG00000196498	E009	26.3434929	0.0007194427	2.965333e-03	1.015975e-02	12	124325420	124325430	11	-	1.195	1.461	0.928
ENSG00000196498	E010	173.4002191	0.0004458841	1.765853e-14	5.611129e-13	12	124325431	124325583	153	-	1.983	2.271	0.964
ENSG00000196498	E011	0.4448795	0.6698914522	5.408395e-01	6.719201e-01	12	124326123	124326179	57	-	0.000	0.222	15.497
ENSG00000196498	E012	3.4849909	0.1511389318	1.675495e-01	2.850014e-01	12	124326180	124326190	11	-	0.368	0.715	1.652
ENSG00000196498	E013	272.6132767	0.0049971350	1.471304e-08	1.758575e-07	12	124326191	124326370	180	-	2.190	2.469	0.934
ENSG00000196498	E014	170.8015380	0.0096997178	2.356135e-05	1.437329e-04	12	124327409	124327546	138	-	1.984	2.268	0.951
ENSG00000196498	E015	172.1005400	0.0013557074	2.074495e-07	1.982680e-06	12	124327547	124327633	87	-	2.036	2.256	0.737
ENSG00000196498	E016	1.7778343	0.1118833821	2.212554e-01	3.519387e-01	12	124327634	124327659	26	-	0.564	0.340	-1.167
ENSG00000196498	E017	5.3497872	0.0585556124	4.483836e-02	9.990348e-02	12	124328532	124329157	626	-	0.955	0.661	-1.163
ENSG00000196498	E018	199.2887816	0.0002365261	1.572792e-09	2.249100e-08	12	124330845	124330898	54	-	2.105	2.315	0.705
ENSG00000196498	E019	3.0311635	0.1232001145	8.058170e-01	8.765481e-01	12	124331475	124332318	844	-	0.564	0.567	0.010
ENSG00000196498	E020	274.1725434	0.0011946736	3.844569e-05	2.225440e-04	12	124332319	124332464	146	-	2.285	2.441	0.522
ENSG00000196498	E021	94.3979350	0.0017891372	2.146623e-03	7.679852e-03	12	124332465	124332467	3	-	1.804	1.982	0.598
ENSG00000196498	E022	239.3775764	0.0041161124	9.861732e-05	5.153721e-04	12	124333130	124333279	150	-	2.195	2.394	0.665
ENSG00000196498	E023	0.9253484	0.0566679397	9.861811e-01	9.953599e-01	12	124334344	124334423	80	-	0.276	0.289	0.088
ENSG00000196498	E024	186.7893717	0.0131840325	4.133657e-03	1.351656e-02	12	124334424	124334617	194	-	2.067	2.294	0.760
ENSG00000196498	E025	4.8650389	0.0032869284	2.546385e-02	6.283278e-02	12	124334618	124335134	517	-	0.909	0.637	-1.092
ENSG00000196498	E026	144.2745149	0.0003341571	3.567183e-06	2.626145e-05	12	124335135	124335280	146	-	1.975	2.168	0.649
ENSG00000196498	E027	166.9477196	0.0021961385	5.176956e-03	1.640943e-02	12	124335483	124335632	150	-	2.081	2.224	0.478
ENSG00000196498	E028	6.1292958	0.0070652470	1.677697e-03	6.211590e-03	12	124335633	124336392	760	-	1.033	0.661	-1.449
ENSG00000196498	E029	235.6416703	0.0001939685	2.541755e-02	6.274061e-02	12	124336753	124337103	351	-	2.266	2.358	0.306
ENSG00000196498	E030	98.5222065	0.0003154255	2.192280e-01	3.494390e-01	12	124337104	124337180	77	-	1.899	1.981	0.276
ENSG00000196498	E031	52.6779034	0.0023383266	1.402797e-01	2.484070e-01	12	124340006	124340006	1	-	1.603	1.723	0.407
ENSG00000196498	E032	154.8572099	0.0002439979	3.056836e-02	7.308468e-02	12	124340007	124340204	198	-	2.076	2.179	0.344
ENSG00000196498	E033	167.3796112	0.0009585892	5.652431e-01	6.923673e-01	12	124340294	124340443	150	-	2.144	2.199	0.184
ENSG00000196498	E034	114.8098340	0.0054832134	6.694856e-01	7.762961e-01	12	124340602	124340694	93	-	1.977	2.040	0.214
ENSG00000196498	E035	84.2898554	0.0041807658	7.704600e-01	8.517719e-01	12	124340695	124340751	57	-	1.850	1.904	0.181
ENSG00000196498	E036	155.1079827	0.0066806510	8.525961e-01	9.086662e-01	12	124341823	124342074	252	-	2.118	2.170	0.172
ENSG00000196498	E037	132.7023835	0.0010929935	9.527413e-01	9.743948e-01	12	124343005	124343226	222	-	2.060	2.097	0.125
ENSG00000196498	E038	200.9889855	0.0073979975	1.309293e-01	2.354363e-01	12	124344597	124344951	355	-	2.284	2.258	-0.086
ENSG00000196498	E039	65.0070887	0.0032409928	3.609596e-01	5.053268e-01	12	124346564	124346592	29	-	1.782	1.771	-0.039
ENSG00000196498	E040	164.9205824	0.0051280551	1.309160e-01	2.354272e-01	12	124346593	124346850	258	-	2.196	2.172	-0.082
ENSG00000196498	E041	2.6477362	0.0060963803	6.241509e-02	1.307124e-01	12	124347402	124347824	423	-	0.699	0.426	-1.260
ENSG00000196498	E042	107.6485463	0.0002682963	2.261495e-03	8.034685e-03	12	124347825	124347911	87	-	2.046	1.970	-0.256
ENSG00000196498	E043	133.1498658	0.0002643437	3.108882e-02	7.407847e-02	12	124348174	124348314	141	-	2.112	2.075	-0.124
ENSG00000196498	E044	0.5244761	0.2701636375	3.135640e-01	4.561729e-01	12	124348315	124348940	626	-	0.277	0.094	-1.878
ENSG00000196498	E045	156.1473800	0.0045737168	5.444084e-03	1.713744e-02	12	124350587	124350737	151	-	2.213	2.130	-0.275
ENSG00000196498	E046	132.3736937	0.0046394573	1.155157e-02	3.246947e-02	12	124354093	124354196	104	-	2.138	2.061	-0.259
ENSG00000196498	E047	110.1317770	0.0041533964	5.012449e-02	1.093876e-01	12	124354478	124354582	105	-	2.041	1.989	-0.175
ENSG00000196498	E048	122.9892573	0.0089705243	1.910376e-01	3.150539e-01	12	124354837	124354939	103	-	2.071	2.045	-0.088
ENSG00000196498	E049	0.5514428	0.0196177238	2.554506e-01	3.923336e-01	12	124355059	124355431	373	-	0.000	0.234	15.599
ENSG00000196498	E050	116.6919548	0.0065925268	4.459250e-02	9.944925e-02	12	124355432	124355571	140	-	2.073	2.011	-0.207
ENSG00000196498	E051	73.4825396	0.0068182078	9.310333e-02	1.799774e-01	12	124356642	124356782	141	-	1.873	1.813	-0.205
ENSG00000196498	E052	22.4718210	0.0008352999	9.210574e-01	9.541784e-01	12	124356783	124356803	21	-	1.313	1.337	0.085
ENSG00000196498	E053	10.0907326	0.0357330501	4.125638e-01	5.561237e-01	12	124356804	124356806	3	-	0.909	1.052	0.533
ENSG00000196498	E054	0.9211812	0.0136968632	8.980872e-02	1.748288e-01	12	124356807	124356850	44	-	0.000	0.341	16.336
ENSG00000196498	E055	66.4677611	0.0007155338	1.242265e-01	2.260157e-01	12	124362126	124362294	169	-	1.813	1.774	-0.130
ENSG00000196498	E056	15.0180341	0.0012290631	7.292911e-01	8.215078e-01	12	124362295	124362297	3	-	1.114	1.178	0.230
ENSG00000196498	E057	70.9244403	0.0023409842	5.261506e-02	1.138107e-01	12	124363679	124363799	121	-	1.855	1.795	-0.203
ENSG00000196498	E058	130.4236434	0.0028337471	6.401597e-03	1.966697e-02	12	124372022	124372459	438	-	2.128	2.054	-0.247
ENSG00000196498	E059	47.7319928	0.0083368742	2.521496e-01	3.884762e-01	12	124372460	124372610	151	-	1.682	1.639	-0.146
ENSG00000196498	E060	9.9648461	0.0019180170	1.719842e-02	4.538120e-02	12	124374413	124374463	51	-	1.143	0.924	-0.802
ENSG00000196498	E061	82.2927682	0.0003644271	4.000941e-04	1.774723e-03	12	124378237	124378384	148	-	1.951	1.840	-0.374
ENSG00000196498	E062	94.2831300	0.0012719473	1.753013e-04	8.581920e-04	12	124385745	124385887	143	-	2.016	1.896	-0.400
ENSG00000196498	E063	0.0000000				12	124388685	124388824	140	-
ENSG00000196498	E064	78.7419767	0.0009048802	1.671341e-03	6.191084e-03	12	124398119	124398181	63	-	1.932	1.830	-0.343
ENSG00000196498	E065	127.9606604	0.0005659108	3.545994e-08	3.934739e-07	12	124400501	124400673	173	-	2.171	2.019	-0.506
ENSG00000196498	E066	112.9152408	0.0011303698	3.881940e-09	5.160493e-08	12	124402404	124402558	155	-	2.137	1.952	-0.617
ENSG00000196498	E067	26.9062272	0.0009412571	2.755123e-04	1.280010e-03	12	124402559	124402561	3	-	1.547	1.332	-0.739
ENSG00000196498	E068	41.7636758	0.0036038156	1.763921e-06	1.388612e-05	12	124419957	124419958	2	-	1.756	1.499	-0.875
ENSG00000196498	E069	95.9661129	0.0007299193	2.768520e-14	8.528257e-13	12	124419959	124420055	97	-	2.106	1.850	-0.861
ENSG00000196498	E070	84.0078144	0.0005085763	1.295264e-11	2.648504e-10	12	124422501	124422555	55	-	2.036	1.798	-0.799
ENSG00000196498	E071	87.8976002	0.0003566627	5.073055e-15	1.744118e-13	12	124426622	124426686	65	-	2.073	1.804	-0.903
ENSG00000196498	E072	92.5325073	0.0063210508	1.217763e-07	1.217037e-06	12	124426687	124426800	114	-	2.083	1.842	-0.809
ENSG00000196498	E073	1.3212103	0.0106240761	2.592944e-01	3.966888e-01	12	124429395	124429612	218	-	0.160	0.386	1.689
ENSG00000196498	E074	72.4490570	0.0037485690	4.454309e-05	2.540586e-04	12	124429613	124429703	91	-	1.936	1.763	-0.581
ENSG00000196498	E075	32.8267167	0.0006406566	3.452462e-04	1.561008e-03	12	124429704	124429706	3	-	1.613	1.423	-0.649
ENSG00000196498	E076	0.0000000				12	124430610	124430614	5	-
ENSG00000196498	E077	48.2090068	0.0005006533	1.423118e-03	5.383604e-03	12	124430615	124430640	26	-	1.742	1.608	-0.454
ENSG00000196498	E078	58.9444039	0.0004000344	1.967288e-05	1.222518e-04	12	124430641	124430685	45	-	1.847	1.679	-0.569
ENSG00000196498	E079	81.4508755	0.0003737761	3.081723e-06	2.299421e-05	12	124430686	124430784	99	-	1.977	1.820	-0.526
ENSG00000196498	E080	43.9858729	0.0005241961	3.180561e-05	1.880787e-04	12	124430785	124430787	3	-	1.735	1.542	-0.655
ENSG00000196498	E081	76.7533461	0.0051120605	4.280585e-07	3.837153e-06	12	124437930	124437996	67	-	1.996	1.765	-0.780
ENSG00000196498	E082	68.1218807	0.0113727532	3.096362e-05	1.836328e-04	12	124449815	124449867	53	-	1.951	1.711	-0.810
ENSG00000196498	E083	51.0948584	0.0111369322	2.069477e-04	9.937297e-04	12	124457106	124457159	54	-	1.821	1.597	-0.760
ENSG00000196498	E084	29.8783589	0.0013300708	4.901152e-05	2.767619e-04	12	124457160	124457162	3	-	1.598	1.365	-0.801
ENSG00000196498	E085	84.0975269	0.0027123257	1.154428e-11	2.378499e-10	12	124466173	124466286	114	-	2.060	1.785	-0.924
ENSG00000196498	E086	103.3743921	0.0064197186	4.807245e-08	5.205888e-07	12	124472952	124473131	180	-	2.131	1.889	-0.814
ENSG00000196498	E087	98.6777529	0.0053404927	4.390432e-07	3.927444e-06	12	124483596	124483773	178	-	2.095	1.881	-0.718
ENSG00000196498	E088	0.4847352	0.2639897329	3.097828e-01	4.521241e-01	12	124483774	124483774	1	-	0.277	0.093	-1.900
ENSG00000196498	E089	0.1482932	0.0430660439	1.000000e+00		12	124486374	124486440	67	-	0.000	0.093	14.010
ENSG00000196498	E090	83.6458652	0.0003540770	8.453301e-11	1.510804e-09	12	124486441	124486568	128	-	2.028	1.804	-0.754
ENSG00000196498	E091	84.3958870	0.0116733836	2.089675e-06	1.619019e-05	12	124495147	124495368	222	-	2.064	1.791	-0.920
ENSG00000196498	E092	2.5913074	0.0547694413	4.385488e-01	5.804210e-01	12	124518140	124518294	155	-	0.614	0.496	-0.546
ENSG00000196498	E093	13.1977951	0.0120075928	2.978334e-05	1.773826e-04	12	124535565	124535611	47	-	1.349	0.949	-1.434
ENSG00000196498	E094	25.4181889	0.0402438307	1.599997e-06	1.271134e-05	12	124567308	124567603	296	-	1.683	1.139	-1.884

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000196498

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3