ENSG00000196118

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000535476 ENSG00000196118 HEK293_OSMI2_2hA HEK293_TMG_2hB CFAP119 protein_coding protein_coding 20.41711 34.31621 9.88842 1.273078 0.3632865 -1.79404 0.517314 0.3768097 0.6948669 0.37680974 0.36852363 0.8657267 0.0403125 0.01136667 0.06816667 0.056800000 0.42304104 0.00218358 FALSE FALSE
ENST00000537986 ENSG00000196118 HEK293_OSMI2_2hA HEK293_TMG_2hB CFAP119 protein_coding retained_intron 20.41711 34.31621 9.88842 1.273078 0.3632865 -1.79404 9.819310 18.0089706 3.5554348 0.72152147 0.17623375 -2.3373667 0.4538167 0.52543333 0.36070000 -0.164733333 0.00218358 0.00218358   FALSE
ENST00000544643 ENSG00000196118 HEK293_OSMI2_2hA HEK293_TMG_2hB CFAP119 protein_coding retained_intron 20.41711 34.31621 9.88842 1.273078 0.3632865 -1.79404 2.242427 3.1967085 0.9552168 0.71574545 0.12255495 -1.7321683 0.1116000 0.09196667 0.09643333 0.004466667 0.94469913 0.00218358   FALSE
ENST00000545825 ENSG00000196118 HEK293_OSMI2_2hA HEK293_TMG_2hB CFAP119 protein_coding protein_coding 20.41711 34.31621 9.88842 1.273078 0.3632865 -1.79404 4.362004 7.0068031 2.5652477 0.07955151 0.06524218 -1.4461027 0.2187667 0.20480000 0.25966667 0.054866667 0.10465862 0.00218358 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000196118 E001 2.646588 0.0060421274 0.656465348 0.766017823 16 30757423 30757423 1 - 0.540 0.461 -0.381
ENSG00000196118 E002 2.943174 0.0053010023 0.861228022 0.914470398 16 30757424 30757424 1 - 0.540 0.510 -0.141
ENSG00000196118 E003 3.536347 0.0052747442 0.765496558 0.848239874 16 30757425 30757430 6 - 0.540 0.593 0.244
ENSG00000196118 E004 4.564091 0.0036065673 0.417023141 0.560409881 16 30757431 30757434 4 - 0.540 0.680 0.618
ENSG00000196118 E005 4.564091 0.0036065673 0.417023141 0.560409881 16 30757435 30757435 1 - 0.540 0.680 0.618
ENSG00000196118 E006 23.148699 0.0351595881 0.101019473 0.192013927 16 30757436 30757466 31 - 1.082 1.308 0.804
ENSG00000196118 E007 147.021509 0.0024927749 0.003501789 0.011730651 16 30757467 30757654 188 - 1.956 2.084 0.429
ENSG00000196118 E008 10.358744 0.0020513032 0.058124472 0.123412797 16 30759012 30759101 90 - 1.125 0.915 -0.772
ENSG00000196118 E009 2.137907 0.0068676893 0.177266515 0.297675946 16 30759102 30759177 76 - 0.611 0.376 -1.164
ENSG00000196118 E010 34.290714 0.0008111018 0.074466270 0.150676744 16 30759178 30759247 70 - 1.535 1.414 -0.416
ENSG00000196118 E011 40.370889 0.0019484825 0.002870840 0.009885706 16 30759342 30759444 103 - 1.651 1.461 -0.648
ENSG00000196118 E012 18.404253 0.0112226684 0.049442241 0.108167767 16 30759445 30759458 14 - 1.329 1.135 -0.686
ENSG00000196118 E013 15.920225 0.0050173546 0.223485558 0.354547703 16 30759459 30759557 99 - 1.215 1.093 -0.436
ENSG00000196118 E014 12.487512 0.0032078921 0.090145706 0.175347902 16 30759558 30759653 96 - 1.163 0.983 -0.655
ENSG00000196118 E015 25.080066 0.0199514957 0.024653809 0.061167806 16 30759654 30759724 71 - 1.476 1.257 -0.761
ENSG00000196118 E016 5.623063 0.0031591974 0.012018039 0.033572517 16 30759725 30759809 85 - 0.983 0.647 -1.327
ENSG00000196118 E017 33.753285 0.0113170587 0.017805218 0.046717521 16 30760037 30760283 247 - 1.587 1.397 -0.652
ENSG00000196118 E018 98.676746 0.0006651668 0.806571039 0.877081247 16 30760284 30760292 9 - 1.878 1.891 0.044
ENSG00000196118 E019 202.357665 0.0018931625 0.020122990 0.051743733 16 30760293 30760453 161 - 2.129 2.214 0.283
ENSG00000196118 E020 66.920593 0.0022057647 0.576488332 0.701913151 16 30760454 30760605 152 - 1.691 1.726 0.121
ENSG00000196118 E021 112.294808 0.0003215163 0.107182134 0.201372678 16 30760606 30760668 63 - 1.882 1.951 0.232
ENSG00000196118 E022 97.256292 0.0024427243 0.237772575 0.371562797 16 30761198 30761229 32 - 1.826 1.888 0.210
ENSG00000196118 E023 50.253594 0.0005116088 0.399504567 0.543253146 16 30761230 30761335 106 - 1.550 1.605 0.185
ENSG00000196118 E024 49.569093 0.0054879664 0.293016925 0.434052980 16 30761336 30761544 209 - 1.519 1.602 0.283
ENSG00000196118 E025 210.988017 0.0004007469 0.010806014 0.030700804 16 30761545 30762221 677 - 2.266 2.198 -0.229