• ENSG00000186522
  • 1 Isoform Switch
  • 2 Differential Exon Usage

ENSG00000186522

1 Isoform Switch

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

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isoform_idColumn filter
gene_idColumn filter
condition_1Column filter
condition_2Column filter
gene_nameColumn filter
gene_biotypeColumn filter
iso_biotypeColumn filter
gene_overall_meanColumn filter
gene_value_1Column filter
gene_value_2Column filter
gene_stderr_1Column filter
gene_stderr_2Column filter
gene_log2_fold_changeColumn filter
iso_overall_meanColumn filter
iso_value_1Column filter
iso_value_2Column filter
iso_stderr_1Column filter
iso_stderr_2Column filter
iso_log2_fold_changeColumn filter
IF_overallColumn filter
IF1Column filter
IF2Column filter
dIFColumn filter
isoform_switch_q_valueColumn filter
gene_switch_q_valueColumn filter
PTCColumn filter
codingPotentialColumn filter
ENST00000356688 ENSG00000186522 HEK293_OSMI2_2hA HEK293_TMG_2hB SEPTIN10 protein_coding protein_coding 13.77707 4.946809 23.78267 0.05783069 0.5799119 2.263033 0.7454268 0.4688209 1.162850 0.33594352 0.6581312 1.292460 0.07696667 0.09366667 0.04823333 -0.04543333 9.488939e-01 3.146802e-05 FALSE TRUE
ENST00000397712 ENSG00000186522 HEK293_OSMI2_2hA HEK293_TMG_2hB SEPTIN10 protein_coding protein_coding 13.77707 4.946809 23.78267 0.05783069 0.5799119 2.263033 0.9772293 0.9279456 1.545308 0.50419969 1.5453079 0.729624 0.11008750 0.18763333 0.06223333 -0.12540000 1.851518e-01 3.146802e-05 FALSE TRUE
ENST00000397714 ENSG00000186522 HEK293_OSMI2_2hA HEK293_TMG_2hB SEPTIN10 protein_coding protein_coding 13.77707 4.946809 23.78267 0.05783069 0.5799119 2.263033 5.5334278 2.5841944 9.352821 0.34183938 1.3426003 1.851657 0.41126667 0.52403333 0.39593333 -0.12810000 5.325810e-01 3.146802e-05 FALSE TRUE
ENST00000415095 ENSG00000186522 HEK293_OSMI2_2hA HEK293_TMG_2hB SEPTIN10 protein_coding protein_coding 13.77707 4.946809 23.78267 0.05783069 0.5799119 2.263033 4.1903438 0.6131001 8.335005 0.11997389 0.2852151 3.743377 0.24417917 0.12410000 0.35150000 0.22740000 3.146802e-05 3.146802e-05 FALSE TRUE
ENST00000437928 ENSG00000186522 HEK293_OSMI2_2hA HEK293_TMG_2hB SEPTIN10 protein_coding protein_coding 13.77707 4.946809 23.78267 0.05783069 0.5799119 2.263033 0.9364681 0.1120785 1.482575 0.03702981 0.1357610 3.611923 0.06100417 0.02253333 0.06260000 0.04006667 5.495894e-02 3.146802e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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groupIDColumn filter
featureIDColumn filter
exonBaseMeanColumn filter
dispersionColumn filter
pvalueColumn filter
padjColumn filter
seqnamesColumn filter
startColumn filter
endColumn filter
widthColumn filter
strandColumn filter
HEK293_TMG_2hBColumn filter
HEK293_OSMI2_2hAColumn filter
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hBColumn filter
ENSG00000186522 E001 1.1414950 0.0134726613 1.863834e-04 9.052823e-04 2 109542799 109542981 183 - 0.062 0.711 4.757
ENSG00000186522 E002 0.8146179 0.1590822427 6.811231e-04 2.830001e-03 2 109542982 109542985 4 - 0.000 0.642 15.481
ENSG00000186522 E003 255.1877559 0.0047672005 1.202199e-20 8.310048e-19 2 109542986 109544020 1035 - 2.213 2.585 1.241
ENSG00000186522 E004 121.7547987 0.0003886941 1.528708e-05 9.738032e-05 2 109544021 109544236 216 - 1.955 2.146 0.641
ENSG00000186522 E005 73.2927475 0.0031979917 3.504678e-02 8.173915e-02 2 109544237 109544324 88 - 1.749 1.898 0.502
ENSG00000186522 E006 15.4558243 0.0021630190 9.232383e-01 9.555965e-01 2 109545385 109545459 75 - 1.127 1.151 0.084
ENSG00000186522 E007 15.1695193 0.0188790823 7.832335e-01 8.608779e-01 2 109545460 109545542 83 - 1.127 1.128 0.002
ENSG00000186522 E008 36.1204557 0.0138148110 8.923568e-01 9.352245e-01 2 109545802 109546029 228 - 1.472 1.518 0.157
ENSG00000186522 E009 17.2119799 0.0042055133 3.805526e-01 5.248240e-01 2 109546030 109546049 20 - 1.187 1.129 -0.209
ENSG00000186522 E010 116.3791812 0.0053163122 1.442179e-01 2.537429e-01 2 109546050 109546237 188 - 1.990 1.951 -0.131
ENSG00000186522 E011 99.3408541 0.0002701113 3.181126e-02 7.549133e-02 2 109553087 109553219 133 - 1.927 1.867 -0.200
ENSG00000186522 E012 1.2448386 0.0127106566 5.581992e-02 1.193800e-01 2 109564215 109564365 151 - 0.207 0.576 2.174
ENSG00000186522 E013 75.8930547 0.0003910508 2.954172e-01 4.365446e-01 2 109564366 109564424 59 - 1.804 1.787 -0.058
ENSG00000186522 E014 94.2618676 0.0003713014 3.050045e-01 4.470402e-01 2 109564425 109564518 94 - 1.894 1.883 -0.036
ENSG00000186522 E015 58.3502974 0.0004138455 3.847032e-01 5.288581e-01 2 109564519 109564534 16 - 1.690 1.675 -0.049
ENSG00000186522 E016 95.4771302 0.0003045237 2.893509e-02 6.987553e-02 2 109565763 109565829 67 - 1.910 1.846 -0.214
ENSG00000186522 E017 79.0956243 0.0003761470 5.262183e-02 1.138188e-01 2 109565830 109565859 30 - 1.828 1.767 -0.208
ENSG00000186522 E018 102.9531748 0.0003312561 6.335699e-04 2.656955e-03 2 109567815 109567918 104 - 1.951 1.833 -0.397
ENSG00000186522 E019 76.5184063 0.0005383206 6.971489e-04 2.888667e-03 2 109567919 109567976 58 - 1.827 1.682 -0.491
ENSG00000186522 E020 128.5500890 0.0011858231 3.453208e-04 1.561224e-03 2 109574581 109574767 187 - 2.046 1.928 -0.394
ENSG00000186522 E021 118.2251903 0.0002954504 5.170070e-02 1.121838e-01 2 109585126 109585321 196 - 1.998 1.955 -0.144
ENSG00000186522 E022 0.3030308 0.3707509018 1.000000e+00   2 109585720 109585720 1 - 0.117 0.000 -10.120
ENSG00000186522 E023 41.7715174 0.0006908679 1.088826e-02 3.089936e-02 2 109585721 109585725 5 - 1.572 1.425 -0.504
ENSG00000186522 E024 46.3812409 0.0005225967 1.568094e-02 4.202443e-02 2 109585726 109585747 22 - 1.614 1.488 -0.432
ENSG00000186522 E025 64.3245703 0.0004159810 5.032092e-03 1.601984e-02 2 109585748 109585838 91 - 1.753 1.628 -0.422
ENSG00000186522 E026 0.6192988 0.0198887370 7.732897e-01 8.537096e-01 2 109593047 109593050 4 - 0.164 0.228 0.591
ENSG00000186522 E027 48.2138725 0.0060273762 6.663829e-03 2.034816e-02 2 109593051 109593119 69 - 1.640 1.466 -0.595
ENSG00000186522 E028 0.1451727 0.0426833969 1.000000e+00   2 109604835 109604933 99 - 0.062 0.000 -9.112
ENSG00000186522 E029 0.4439371 0.0215895222 6.391069e-01 7.525726e-01 2 109613112 109613420 309 - 0.164 0.000 -10.698
ENSG00000186522 E030 0.1515154 0.0431525149 1.000000e+00   2 109613421 109613510 90 - 0.062 0.000 -9.113
ENSG00000186522 E031 45.1930539 0.0006251954 1.106667e-02 3.132541e-02 2 109613798 109614143 346 - 1.606 1.468 -0.473