ENSG00000184792

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000332585 ENSG00000184792 HEK293_OSMI2_2hA HEK293_TMG_2hB OSBP2 protein_coding protein_coding 2.788271 3.869403 2.331565 0.3175624 0.1844401 -0.7283618 1.1544435 1.4289306 1.0117721 0.2589355 0.07442392 -0.4939235 0.40802083 0.37330000 0.43490000 0.06160000 7.678806e-01 9.827991e-05 FALSE TRUE
ENST00000431368 ENSG00000184792 HEK293_OSMI2_2hA HEK293_TMG_2hB OSBP2 protein_coding protein_coding 2.788271 3.869403 2.331565 0.3175624 0.1844401 -0.7283618 0.2557852 0.7044459 0.0000000 0.2071247 0.00000000 -6.1587528 0.08450833 0.18996667 0.00000000 -0.18996667 9.827991e-05 9.827991e-05 FALSE TRUE
ENST00000452656 ENSG00000184792 HEK293_OSMI2_2hA HEK293_TMG_2hB OSBP2 protein_coding protein_coding 2.788271 3.869403 2.331565 0.3175624 0.1844401 -0.7283618 0.2378601 0.3151227 0.3682474 0.2157222 0.07135271 0.2183458 0.08476250 0.07363333 0.16320000 0.08956667 4.858797e-01 9.827991e-05 FALSE TRUE
ENST00000454145 ENSG00000184792 HEK293_OSMI2_2hA HEK293_TMG_2hB OSBP2 protein_coding protein_coding 2.788271 3.869403 2.331565 0.3175624 0.1844401 -0.7283618 0.1039574 0.0000000 0.2376441 0.0000000 0.18410117 4.6301962 0.03956250 0.00000000 0.09376667 0.09376667 1.782954e-01 9.827991e-05 FALSE FALSE
MSTRG.21942.4 ENSG00000184792 HEK293_OSMI2_2hA HEK293_TMG_2hB OSBP2 protein_coding   2.788271 3.869403 2.331565 0.3175624 0.1844401 -0.7283618 0.5489239 1.0083027 0.3644494 0.1959597 0.11452700 -1.4433237 0.18112917 0.25776667 0.15276667 -0.10500000 4.174669e-01 9.827991e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000184792 E001 0.0000000       22 30693782 30694072 291 +      
ENSG00000184792 E002 0.0000000       22 30694076 30694205 130 +      
ENSG00000184792 E003 0.0000000       22 30694206 30694207 2 +      
ENSG00000184792 E004 0.5483223 0.0199141013 1.000000000 1.00000000 22 30694208 30694309 102 + 0.160 0.169 0.101
ENSG00000184792 E005 0.5483223 0.0199141013 1.000000000 1.00000000 22 30694310 30694344 35 + 0.160 0.169 0.101
ENSG00000184792 E006 0.6579068 0.3419911884 0.564348484 0.69165024 22 30694874 30694888 15 + 0.276 0.170 -0.890
ENSG00000184792 E007 19.6652201 0.0239085530 0.309088718 0.45137439 22 30694889 30695375 487 + 1.340 1.264 -0.266
ENSG00000184792 E008 15.6656659 0.0069227198 0.743544407 0.83217456 22 30695376 30695553 178 + 1.195 1.190 -0.018
ENSG00000184792 E009 18.8279184 0.0011039427 0.700464109 0.79992781 22 30741161 30741369 209 + 1.264 1.259 -0.016
ENSG00000184792 E010 0.0000000       22 30764253 30764335 83 +      
ENSG00000184792 E011 0.0000000       22 30764336 30764392 57 +      
ENSG00000184792 E012 0.0000000       22 30770583 30770659 77 +      
ENSG00000184792 E013 0.0000000       22 30770660 30770681 22 +      
ENSG00000184792 E014 0.0000000       22 30773123 30773245 123 +      
ENSG00000184792 E015 0.0000000       22 30803086 30803177 92 +      
ENSG00000184792 E016 0.8470867 0.0143596276 0.229393851 0.36171612 22 30822516 30822709 194 + 0.368 0.169 -1.485
ENSG00000184792 E017 0.0000000       22 30842653 30842710 58 +      
ENSG00000184792 E018 0.0000000       22 30844483 30844687 205 +      
ENSG00000184792 E019 28.7468285 0.0012548729 0.525434803 0.65880874 22 30870429 30870682 254 + 1.442 1.427 -0.051
ENSG00000184792 E020 0.0000000       22 30872309 30872523 215 +      
ENSG00000184792 E021 1.0716524 0.0120474549 0.996502082 1.00000000 22 30881681 30881802 122 + 0.276 0.291 0.100
ENSG00000184792 E022 28.2815497 0.0008291361 0.877789974 0.92551496 22 30887426 30887618 193 + 1.421 1.438 0.060
ENSG00000184792 E023 0.0000000       22 30887619 30887622 4 +      
ENSG00000184792 E024 9.3465395 0.0131879134 0.845345645 0.90382187 22 30888223 30888226 4 + 0.976 0.982 0.024
ENSG00000184792 E025 28.9581412 0.0164672235 0.683422086 0.78662072 22 30888227 30888340 114 + 1.390 1.462 0.248
ENSG00000184792 E026 14.8816240 0.0137314648 0.685229662 0.78803096 22 30889177 30889179 3 + 1.114 1.191 0.275
ENSG00000184792 E027 22.2074146 0.0049697988 0.460989387 0.60096652 22 30889180 30889234 55 + 1.264 1.356 0.323
ENSG00000184792 E028 11.5148762 0.0072067855 0.919581539 0.95320200 22 30889490 30889519 30 + 1.050 1.069 0.068
ENSG00000184792 E029 18.5907943 0.0162087939 0.957367338 0.97726897 22 30889520 30889636 117 + 1.231 1.270 0.139
ENSG00000184792 E030 32.7668715 0.0007165927 0.118875131 0.21833589 22 30890728 30890948 221 + 1.536 1.468 -0.235
ENSG00000184792 E031 17.2448981 0.0070178367 0.017723011 0.04653857 22 30890949 30890973 25 + 1.340 1.158 -0.643
ENSG00000184792 E032 28.5635509 0.0008021709 0.003022559 0.01033283 22 30893122 30893242 121 + 1.542 1.378 -0.564
ENSG00000184792 E033 29.7275688 0.0024142418 0.020585081 0.05271828 22 30893463 30893566 104 + 1.530 1.404 -0.435
ENSG00000184792 E034 31.6865075 0.0008215976 0.807060627 0.87744191 22 30893638 30893733 96 + 1.469 1.481 0.041
ENSG00000184792 E035 0.7718438 0.0459747065 0.723459213 0.81729545 22 30893734 30893816 83 + 0.160 0.235 0.694
ENSG00000184792 E036 34.6678145 0.0070145127 0.413382519 0.55688264 22 30893817 30894001 185 + 1.449 1.536 0.298
ENSG00000184792 E037 0.8094091 0.0161501842 0.231086719 0.36377048 22 30894002 30894463 462 + 0.368 0.169 -1.486
ENSG00000184792 E038 32.9928719 0.0177983255 0.609038189 0.72859597 22 30905837 30906069 233 + 1.442 1.514 0.247
ENSG00000184792 E039 1.5436135 0.0096930166 0.469482737 0.60871714 22 30906194 30906196 3 + 0.276 0.426 0.906
ENSG00000184792 E040 139.0906823 0.0207546356 0.020684153 0.05292192 22 30906197 30907824 1628 + 1.988 2.157 0.564