ENSG00000182796

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000478241 ENSG00000182796 HEK293_OSMI2_2hA HEK293_TMG_2hB TMEM198B transcribed_unitary_pseudogene processed_transcript 11.09502 10.91692 9.871315 1.016487 0.4279926 -0.1451118 1.170843 0.9971162 1.0348184 0.11540690 0.25636698 0.053022005 0.10540833 0.09296667 0.10530000 0.01233333 0.9390545713 2.47656e-05 FALSE TRUE
ENST00000482378 ENSG00000182796 HEK293_OSMI2_2hA HEK293_TMG_2hB TMEM198B transcribed_unitary_pseudogene processed_transcript 11.09502 10.91692 9.871315 1.016487 0.4279926 -0.1451118 1.506846 2.6889674 0.6764068 0.40263659 0.07702619 -1.975271839 0.13296250 0.24713333 0.06913333 -0.17800000 0.0000247656 2.47656e-05 TRUE FALSE
ENST00000484016 ENSG00000182796 HEK293_OSMI2_2hA HEK293_TMG_2hB TMEM198B transcribed_unitary_pseudogene transcribed_unitary_pseudogene 11.09502 10.91692 9.871315 1.016487 0.4279926 -0.1451118 1.351516 0.9320811 1.0997981 0.06315641 0.29218272 0.236374084 0.11779583 0.08710000 0.11116667 0.02406667 0.8188040288 2.47656e-05 TRUE TRUE
ENST00000487582 ENSG00000182796 HEK293_OSMI2_2hA HEK293_TMG_2hB TMEM198B transcribed_unitary_pseudogene processed_transcript 11.09502 10.91692 9.871315 1.016487 0.4279926 -0.1451118 1.078575 0.9564060 0.9622286 0.07470579 0.04054048 0.008666051 0.09240417 0.08786667 0.09813333 0.01026667 0.8490615975 2.47656e-05 TRUE FALSE
ENST00000635977 ENSG00000182796 HEK293_OSMI2_2hA HEK293_TMG_2hB TMEM198B transcribed_unitary_pseudogene processed_transcript 11.09502 10.91692 9.871315 1.016487 0.4279926 -0.1451118 1.836644 1.2004731 2.0533963 0.41341338 0.31080084 0.769449902 0.17385000 0.10506667 0.20790000 0.10283333 0.1409831345 2.47656e-05 FALSE FALSE
ENST00000636790 ENSG00000182796 HEK293_OSMI2_2hA HEK293_TMG_2hB TMEM198B transcribed_unitary_pseudogene processed_transcript 11.09502 10.91692 9.871315 1.016487 0.4279926 -0.1451118 1.494825 1.1207567 1.6739058 0.20796880 0.61177946 0.574522837 0.13079583 0.10156667 0.16703333 0.06546667 0.7297950009 2.47656e-05   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000182796 E001 6.374295 0.0025834238 8.378359e-01 8.986056e-01 12 55829608 55829693 86 + 0.841 0.855 0.055
ENSG00000182796 E002 4.894282 0.0032798686 9.788892e-01 9.908456e-01 12 55829694 55829725 32 + 0.759 0.745 -0.059
ENSG00000182796 E003 5.557588 0.0036177448 6.222004e-01 7.390358e-01 12 55829726 55829776 51 + 0.841 0.765 -0.298
ENSG00000182796 E004 4.567504 0.0151822636 5.125139e-01 6.474372e-01 12 55829777 55829800 24 + 0.659 0.746 0.362
ENSG00000182796 E005 7.299946 0.0030793215 6.926589e-01 7.938424e-01 12 55829801 55829825 25 + 0.930 0.871 -0.224
ENSG00000182796 E006 33.118780 0.0026165438 1.201699e-02 3.357197e-02 12 55829960 55830628 669 + 1.612 1.440 -0.588
ENSG00000182796 E007 12.923395 0.0014133285 2.431613e-02 6.046666e-02 12 55830629 55830768 140 + 1.255 1.038 -0.779
ENSG00000182796 E008 10.838377 0.0016285336 6.971088e-02 1.428890e-01 12 55830769 55830827 59 + 1.171 0.981 -0.692
ENSG00000182796 E009 8.383707 0.0023325998 2.625863e-01 4.003719e-01 12 55830828 55830832 5 + 1.037 0.901 -0.505
ENSG00000182796 E010 8.382663 0.0024051124 1.627977e-01 2.787911e-01 12 55830833 55830838 6 + 1.052 0.886 -0.618
ENSG00000182796 E011 8.161218 0.0026303416 1.278741e-01 2.312132e-01 12 55830839 55830840 2 + 1.052 0.871 -0.677
ENSG00000182796 E012 8.165382 0.0022030552 3.323425e-01 4.759815e-01 12 55830841 55830842 2 + 1.021 0.901 -0.447
ENSG00000182796 E013 10.407791 0.0044347294 2.556032e-01 3.925110e-01 12 55830843 55830853 11 + 1.122 0.993 -0.472
ENSG00000182796 E014 17.109532 0.0011103263 1.063422e-01 2.001471e-01 12 55830854 55830879 26 + 1.326 1.182 -0.506
ENSG00000182796 E015 22.318858 0.0009167317 7.421460e-01 8.311401e-01 12 55830880 55830922 43 + 1.372 1.335 -0.128
ENSG00000182796 E016 37.787610 0.0010235491 6.669923e-01 7.743482e-01 12 55830923 55831083 161 + 1.595 1.557 -0.129
ENSG00000182796 E017 7.463132 0.0565704776 2.191553e-01 3.493485e-01 12 55831084 55831124 41 + 1.037 0.821 -0.816
ENSG00000182796 E018 16.543269 0.0462268026 4.254121e-02 9.570825e-02 12 55831125 55831256 132 + 1.380 1.097 -0.998
ENSG00000182796 E019 24.165518 0.0311265885 6.628168e-03 2.025856e-02 12 55831257 55831349 93 + 1.550 1.239 -1.078
ENSG00000182796 E020 18.662453 0.0311770691 1.398960e-03 5.303652e-03 12 55831350 55831532 183 + 1.464 1.098 -1.287
ENSG00000182796 E021 8.869878 0.0714865954 2.968716e-02 7.134536e-02 12 55831533 55831573 41 + 1.160 0.811 -1.298
ENSG00000182796 E022 12.589946 0.0355104712 1.813837e-01 3.029811e-01 12 55832159 55832333 175 + 1.226 1.038 -0.674
ENSG00000182796 E023 9.141885 0.0313532589 4.047491e-01 5.484518e-01 12 55832847 55832870 24 + 1.067 0.942 -0.462
ENSG00000182796 E024 11.918108 0.0220977146 1.985693e-01 3.244010e-01 12 55832871 55832958 88 + 1.194 1.035 -0.571
ENSG00000182796 E025 24.692197 0.0008791326 2.560518e-01 3.930021e-01 12 55832959 55833014 56 + 1.452 1.361 -0.314
ENSG00000182796 E026 16.220969 0.0011766786 6.189178e-02 1.297999e-01 12 55833015 55833038 24 + 1.317 1.150 -0.591
ENSG00000182796 E027 24.244126 0.0065727807 6.783937e-01 7.828846e-01 12 55833039 55833125 87 + 1.407 1.362 -0.154
ENSG00000182796 E028 49.396909 0.0031844017 8.599938e-01 9.136976e-01 12 55833126 55833446 321 + 1.682 1.679 -0.009
ENSG00000182796 E029 42.288155 0.0005968606 2.670981e-01 4.053846e-01 12 55833447 55833541 95 + 1.586 1.634 0.163
ENSG00000182796 E030 5.055235 0.0035095224 5.451974e-01 6.755952e-01 12 55833542 55833588 47 + 0.815 0.723 -0.369
ENSG00000182796 E031 3.235497 0.0054434749 9.225892e-01 9.551698e-01 12 55834285 55834358 74 + 0.619 0.624 0.022
ENSG00000182796 E032 7.678735 0.0119337327 5.203714e-01 6.543478e-01 12 55834569 55834726 158 + 0.987 0.899 -0.328
ENSG00000182796 E033 53.760306 0.0039607254 8.867293e-02 1.730909e-01 12 55834851 55835039 189 + 1.667 1.751 0.283
ENSG00000182796 E034 54.914917 0.0004246822 9.808604e-02 1.876033e-01 12 55835040 55835219 180 + 1.685 1.752 0.224
ENSG00000182796 E035 57.752321 0.0004660225 7.296945e-02 1.482768e-01 12 55835220 55835463 244 + 1.703 1.774 0.241
ENSG00000182796 E036 51.161031 0.0005325733 3.448841e-03 1.157846e-02 12 55835464 55835615 152 + 1.608 1.743 0.459
ENSG00000182796 E037 81.112451 0.0004066071 1.454946e-08 1.740451e-07 12 55835616 55836037 422 + 1.745 1.964 0.738
ENSG00000182796 E038 33.279601 0.0006951239 1.014375e-05 6.731248e-05 12 55836038 55836125 88 + 1.317 1.595 0.954
ENSG00000182796 E039 32.241520 0.0029551210 1.388283e-05 8.923327e-05 12 55836126 55836246 121 + 1.283 1.581 1.028