ENSG00000182648

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000418309 ENSG00000182648 HEK293_OSMI2_2hA HEK293_TMG_2hB LINC01006 lncRNA lncRNA 2.235146 3.406818 1.114127 0.4972981 0.0820092 -1.603849 0.39402012 0.89862551 0.28012157 0.08251274 0.04960048 -1.64702826 0.17210833 0.267766667 0.25096667 -0.01680000 0.89374635 0.04244353   FALSE
ENST00000447933 ENSG00000182648 HEK293_OSMI2_2hA HEK293_TMG_2hB LINC01006 lncRNA lncRNA 2.235146 3.406818 1.114127 0.4972981 0.0820092 -1.603849 0.18996337 0.24723482 0.26256705 0.12517322 0.03165185 0.08352526 0.10092083 0.072433333 0.23506667 0.16263333 0.19698475 0.04244353   FALSE
ENST00000458645 ENSG00000182648 HEK293_OSMI2_2hA HEK293_TMG_2hB LINC01006 lncRNA lncRNA 2.235146 3.406818 1.114127 0.4972981 0.0820092 -1.603849 0.03063761 0.01886044 0.08172463 0.01886044 0.04416213 1.66821566 0.01842917 0.006966667 0.06946667 0.06250000 0.16357223 0.04244353 TRUE FALSE
ENST00000661282 ENSG00000182648 HEK293_OSMI2_2hA HEK293_TMG_2hB LINC01006 lncRNA lncRNA 2.235146 3.406818 1.114127 0.4972981 0.0820092 -1.603849 0.11050758 0.27555746 0.10140503 0.27555746 0.10140503 -1.35796673 0.05082083 0.063100000 0.08170000 0.01860000 0.92278204 0.04244353 FALSE FALSE
ENST00000664734 ENSG00000182648 HEK293_OSMI2_2hA HEK293_TMG_2hB LINC01006 lncRNA lncRNA 2.235146 3.406818 1.114127 0.4972981 0.0820092 -1.603849 0.09074425 0.07476434 0.11178774 0.02744494 0.02050923 0.52283961 0.05239583 0.024533333 0.10290000 0.07836667 0.04244353 0.04244353   FALSE
ENST00000689604 ENSG00000182648 HEK293_OSMI2_2hA HEK293_TMG_2hB LINC01006 lncRNA lncRNA 2.235146 3.406818 1.114127 0.4972981 0.0820092 -1.603849 0.48580743 0.77255015 0.14937892 0.40719821 0.08321291 -2.29572242 0.22770417 0.269400000 0.14706667 -0.12233333 0.89599635 0.04244353   TRUE
ENST00000692446 ENSG00000182648 HEK293_OSMI2_2hA HEK293_TMG_2hB LINC01006 lncRNA lncRNA 2.235146 3.406818 1.114127 0.4972981 0.0820092 -1.603849 0.75344178 1.03235986 0.09779850 0.58905759 0.09779850 -3.27344447 0.29389583 0.267566667 0.08576667 -0.18180000 0.62788592 0.04244353   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000182648 E001 0.0000000       7 156388922 156389183 262 -      
ENSG00000182648 E002 0.0000000       7 156432352 156432522 171 -      
ENSG00000182648 E003 0.0000000       7 156432523 156432879 357 -      
ENSG00000182648 E004 0.0000000       7 156435759 156435833 75 -      
ENSG00000182648 E005 0.0000000       7 156436980 156437787 808 -      
ENSG00000182648 E006 0.0000000       7 156437788 156438048 261 -      
ENSG00000182648 E007 0.0000000       7 156438049 156438723 675 -      
ENSG00000182648 E008 0.0000000       7 156438724 156438779 56 -      
ENSG00000182648 E009 0.0000000       7 156438780 156438995 216 -      
ENSG00000182648 E010 0.0000000       7 156441230 156441380 151 -      
ENSG00000182648 E011 0.1817044 0.0385628199 1.000000000   7 156444249 156445826 1578 - 0.000 0.067 7.619
ENSG00000182648 E012 0.0000000       7 156446135 156446260 126 -      
ENSG00000182648 E013 0.1482932 0.0462139337 1.000000000   7 156471126 156471154 29 - 0.000 0.067 9.632
ENSG00000182648 E014 0.7739347 0.0150545435 0.066014305 0.136726240 7 156471155 156472096 942 - 0.463 0.125 -2.517
ENSG00000182648 E015 0.2924217 0.0301774198 0.024742464   7 156472097 156472115 19 - 0.356 0.000 -14.225
ENSG00000182648 E016 0.1472490 0.0426030747 0.122885153   7 156472116 156472126 11 - 0.214 0.000 -13.327
ENSG00000182648 E017 1.2146496 0.0112990731 0.013444084 0.036950216 7 156472127 156472195 69 - 0.621 0.176 -2.670
ENSG00000182648 E018 5.8323156 0.0029481422 0.013090855 0.036119824 7 156472196 156472711 516 - 0.996 0.653 -1.347
ENSG00000182648 E019 0.0000000       7 156479217 156479682 466 -      
ENSG00000182648 E020 0.1482932 0.0462139337 1.000000000   7 156479683 156480664 982 - 0.000 0.067 9.632
ENSG00000182648 E021 0.0000000       7 156480665 156481376 712 -      
ENSG00000182648 E022 0.1817044 0.0385628199 1.000000000   7 156481377 156481617 241 - 0.000 0.067 9.643
ENSG00000182648 E023 0.0000000       7 156481618 156481620 3 -      
ENSG00000182648 E024 0.0000000       7 156584160 156584200 41 -      
ENSG00000182648 E025 0.7739347 0.0150545435 0.066014305 0.136726240 7 156584201 156584520 320 - 0.463 0.125 -2.517
ENSG00000182648 E026 0.0000000       7 156603051 156603195 145 -      
ENSG00000182648 E027 3.6000473 0.0148080795 0.450848429 0.591884427 7 156603618 156603784 167 - 0.463 0.585 0.576
ENSG00000182648 E028 5.4499153 0.0044159759 0.206363153 0.334155699 7 156603785 156603911 127 - 0.867 0.669 -0.793
ENSG00000182648 E029 0.0000000       7 156605132 156605187 56 -      
ENSG00000182648 E030 10.8571940 0.0020859836 0.120871228 0.221194243 7 156605188 156605380 193 - 1.116 0.929 -0.688
ENSG00000182648 E031 4.6467977 0.0038169686 0.159959857 0.275062539 7 156605658 156605764 107 - 0.827 0.602 -0.931
ENSG00000182648 E032 3.3192487 0.1925329055 0.002588717 0.009031595 7 156619946 156621622 1677 - 0.995 0.357 -2.797
ENSG00000182648 E033 0.0000000       7 156638363 156638365 3 -      
ENSG00000182648 E034 0.1482932 0.0462139337 1.000000000   7 156638366 156638403 38 - 0.000 0.067 9.632
ENSG00000182648 E035 10.2443982 0.0432926919 0.582704113 0.706990042 7 156638404 156638947 544 - 0.903 0.964 0.230
ENSG00000182648 E036 11.2661157 0.0016632385 0.728916298 0.821246794 7 156638948 156639424 477 - 0.967 0.985 0.069
ENSG00000182648 E037 1.8058437 0.0083411444 0.329930421 0.473503291 7 156639425 156639431 7 - 0.214 0.398 1.239
ENSG00000182648 E038 28.8187001 0.0009094357 0.001525869 0.005720560 7 156639432 156639948 517 - 1.157 1.389 0.817
ENSG00000182648 E039 11.1060769 0.0016529876 0.008232561 0.024373851 7 156639949 156640003 55 - 0.682 1.021 1.317
ENSG00000182648 E040 16.9130029 0.0013508828 0.016291591 0.043367707 7 156640004 156640535 532 - 0.936 1.171 0.860
ENSG00000182648 E041 5.1586729 0.0722452615 0.701725614 0.800768687 7 156640536 156640654 119 - 0.736 0.664 -0.301