ENSG00000182220

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-2 / 2
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000636409	ENSG00000182220	HEK293_OSMI2_2hA	HEK293_TMG_2hB	ATP6AP2	protein_coding	protein_coding	64.94285	34.03079	85.04308	3.959784	1.861373	1.321099	3.88503	0.9907513	6.776645	0.5298902	0.8015628	2.761615	0.05767083	0.02733333	0.07933333	0.0520	0.427532719	0.001660629	FALSE	TRUE
ENST00000636580	ENSG00000182220	HEK293_OSMI2_2hA	HEK293_TMG_2hB	ATP6AP2	protein_coding	protein_coding	64.94285	34.03079	85.04308	3.959784	1.861373	1.321099	48.08506	30.0520974	60.179957	3.6890092	2.7660095	1.001577	0.77469167	0.88190000	0.70960000	-0.1723	0.001660629	0.001660629	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 56
Columns:
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groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000182220	E001	0.0000000				X	40579372	40579390	19	+
ENSG00000182220	E002	0.0000000				X	40579707	40579747	41	+
ENSG00000182220	E003	0.2966881	0.0271012711	5.677561e-01		X	40580894	40580899	6	+	0.154	0.000	-10.425
ENSG00000182220	E004	0.4449813	0.0211126179	9.176397e-01	9.519601e-01	X	40580900	40580909	10	+	0.154	0.175	0.228
ENSG00000182220	E005	0.5901540	0.0200283248	8.485941e-01	9.059912e-01	X	40580910	40580912	3	+	0.214	0.175	-0.356
ENSG00000182220	E006	2.5088852	0.0060113117	1.343961e-02	3.693952e-02	X	40580913	40580936	24	+	0.643	0.176	-2.770
ENSG00000182220	E007	2.9506322	0.0095697579	5.363147e-03	1.691751e-02	X	40580937	40580939	3	+	0.702	0.176	-3.018
ENSG00000182220	E008	5.4627397	0.0036369890	1.704985e-05	1.074174e-04	X	40580940	40580942	3	+	0.937	0.176	-3.940
ENSG00000182220	E009	8.4812374	0.0066097536	1.628511e-04	8.041403e-04	X	40580943	40580948	6	+	1.081	0.543	-2.149
ENSG00000182220	E010	20.2575712	0.0008744948	2.032144e-03	7.326461e-03	X	40580949	40580957	9	+	1.379	1.113	-0.940
ENSG00000182220	E011	23.1833487	0.0008184887	1.424560e-03	5.388520e-03	X	40580958	40580959	2	+	1.434	1.175	-0.905
ENSG00000182220	E012	30.6874136	0.0006518069	1.275092e-05	8.266657e-05	X	40580960	40580965	6	+	1.562	1.242	-1.109
ENSG00000182220	E013	49.6204371	0.0005007775	2.127491e-08	2.468591e-07	X	40580966	40580969	4	+	1.768	1.438	-1.124
ENSG00000182220	E014	79.6241929	0.0102473453	1.352203e-05	8.714183e-05	X	40580970	40580981	12	+	1.966	1.657	-1.042
ENSG00000182220	E015	123.6128743	0.0100638374	1.694548e-04	8.327549e-04	X	40580982	40580994	13	+	2.141	1.900	-0.808
ENSG00000182220	E016	125.0156728	0.0121769660	4.402472e-04	1.928985e-03	X	40580995	40580997	3	+	2.146	1.905	-0.806
ENSG00000182220	E017	174.4812409	0.0149274121	5.811031e-03	1.811615e-02	X	40580998	40581035	38	+	2.279	2.083	-0.656
ENSG00000182220	E018	195.2805566	0.0156065379	1.284977e-02	3.556393e-02	X	40581036	40581071	36	+	2.323	2.145	-0.594
ENSG00000182220	E019	179.7955305	0.0202023990	6.745690e-02	1.391239e-01	X	40581072	40581102	31	+	2.279	2.132	-0.491
ENSG00000182220	E020	169.4855466	0.0124663229	7.555446e-02	1.524017e-01	X	40588986	40588997	12	+	2.246	2.129	-0.392
ENSG00000182220	E021	363.3773273	0.0044510628	7.054642e-02	1.442474e-01	X	40588998	40589116	119	+	2.564	2.487	-0.254
ENSG00000182220	E022	4.0922515	0.0039498737	3.707589e-01	5.151727e-01	X	40589117	40591233	2117	+	0.643	0.777	0.552
ENSG00000182220	E023	261.0022194	0.0002651648	6.215981e-03	1.918289e-02	X	40591234	40591258	25	+	2.417	2.353	-0.213
ENSG00000182220	E024	256.7016649	0.0012291855	3.920927e-02	8.956938e-02	X	40591259	40591269	11	+	2.409	2.350	-0.197
ENSG00000182220	E025	429.5258615	0.0019048622	4.208417e-01	5.640171e-01	X	40591270	40591365	96	+	2.621	2.598	-0.077
ENSG00000182220	E026	1.0382558	0.0790840894	5.534293e-01	6.825792e-01	X	40591366	40592502	1137	+	0.267	0.394	0.796
ENSG00000182220	E027	0.1451727	0.0439302326	1.000000e+00		X	40595854	40595947	94	+	0.084	0.000	-11.233
ENSG00000182220	E028	0.6256415	0.0172671820	8.511080e-01	9.076777e-01	X	40596918	40597248	331	+	0.214	0.176	-0.354
ENSG00000182220	E029	240.3580028	0.0015483792	5.765855e-01	7.019761e-01	X	40597249	40597252	4	+	2.368	2.351	-0.056
ENSG00000182220	E030	385.8330518	0.0002282807	5.713304e-01	6.976316e-01	X	40597253	40597336	84	+	2.570	2.563	-0.026
ENSG00000182220	E031	210.1188894	0.0001783076	2.957528e-01	4.369043e-01	X	40597337	40597344	8	+	2.313	2.290	-0.079
ENSG00000182220	E032	210.4298342	0.0001735427	4.167737e-01	5.601582e-01	X	40597527	40597528	2	+	2.312	2.295	-0.057
ENSG00000182220	E033	334.9678143	0.0001583293	8.915783e-01	9.347576e-01	X	40597529	40597566	38	+	2.504	2.511	0.023
ENSG00000182220	E034	282.4642945	0.0001558062	4.312608e-01	5.738280e-01	X	40597567	40597570	4	+	2.425	2.447	0.073
ENSG00000182220	E035	387.6157889	0.0001263093	6.020788e-01	7.231010e-01	X	40597571	40597617	47	+	2.565	2.579	0.047
ENSG00000182220	E036	391.4959732	0.0009502557	5.200818e-01	6.541092e-01	X	40597618	40597664	47	+	2.568	2.589	0.068
ENSG00000182220	E037	0.2987644	0.0273887890	5.670047e-01		X	40597665	40597751	87	+	0.154	0.000	-12.480
ENSG00000182220	E038	1.1467936	0.0114998462	2.665858e-02	6.528292e-02	X	40597752	40598651	900	+	0.154	0.543	2.551
ENSG00000182220	E039	0.4460135	0.0336052177	3.267255e-01	4.701808e-01	X	40598652	40598680	29	+	0.214	0.000	-12.955
ENSG00000182220	E040	386.9745959	0.0032851399	4.392114e-01	5.809794e-01	X	40598681	40598734	54	+	2.575	2.558	-0.057
ENSG00000182220	E041	0.0000000				X	40598735	40598935	201	+
ENSG00000182220	E042	0.5869198	0.1730725996	2.476863e-01	3.832205e-01	X	40598936	40599018	83	+	0.267	0.000	-12.577
ENSG00000182220	E043	2.5560260	0.0059372141	7.572705e-02	1.526666e-01	X	40599019	40599591	573	+	0.622	0.300	-1.677
ENSG00000182220	E044	326.6595862	0.0034288354	3.833366e-01	5.275201e-01	X	40599592	40599606	15	+	2.503	2.481	-0.072
ENSG00000182220	E045	402.1438760	0.0009301328	1.301736e-01	2.344062e-01	X	40599607	40599648	42	+	2.596	2.565	-0.104
ENSG00000182220	E046	504.5898476	0.0011054198	7.112160e-01	8.082024e-01	X	40599649	40599741	93	+	2.685	2.682	-0.011
ENSG00000182220	E047	2.2207299	0.0064324204	2.586309e-02	6.365956e-02	X	40599742	40600761	1020	+	0.599	0.176	-2.578
ENSG00000182220	E048	236.2450999	0.0001789871	1.778873e-01	2.984867e-01	X	40600762	40600768	7	+	2.342	2.379	0.125
ENSG00000182220	E049	252.7577748	0.0001706065	8.621169e-01	9.151189e-01	X	40600769	40600777	9	+	2.382	2.390	0.028
ENSG00000182220	E050	240.1463953	0.0001950502	6.603866e-01	7.690546e-01	X	40600778	40600781	4	+	2.364	2.357	-0.023
ENSG00000182220	E051	455.2393557	0.0005769106	6.410734e-03	1.968897e-02	X	40600782	40600881	100	+	2.618	2.677	0.196
ENSG00000182220	E052	0.6277178	0.0323895865	8.535809e-01	9.093939e-01	X	40600882	40600929	48	+	0.214	0.176	-0.354
ENSG00000182220	E053	0.6590396	0.0256841869	8.543181e-01	9.098881e-01	X	40603337	40603439	103	+	0.214	0.176	-0.352
ENSG00000182220	E054	3.5450606	0.0045017022	5.319269e-01	6.643195e-01	X	40605121	40605560	440	+	0.599	0.698	0.423
ENSG00000182220	E055	246.9482482	0.0001706530	7.102160e-03	2.149299e-02	X	40605561	40605563	3	+	2.351	2.420	0.229
ENSG00000182220	E056	1692.1824166	0.0008151805	5.247457e-28	7.440980e-26	X	40605564	40606848	1285	+	3.149	3.303	0.514

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000182220

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3