ENSG00000179698

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000525150 ENSG00000179698 HEK293_OSMI2_2hA HEK293_TMG_2hB WDR97 protein_coding retained_intron 0.2333291 0.1254603 0.3445566 0.01297224 0.01946764 1.388146 0.01296971 0.044830234 0.0000000 0.013125315 0.000000000 -2.454972 0.0831125 0.3432 0.0000000 -0.34320000 0.02323678 0.02323678 FALSE TRUE
ENST00000528691 ENSG00000179698 HEK293_OSMI2_2hA HEK293_TMG_2hB WDR97 protein_coding retained_intron 0.2333291 0.1254603 0.3445566 0.01297224 0.01946764 1.388146 0.07253368 0.004652865 0.1277222 0.004652865 0.017681020 3.232507 0.2687833 0.0446 0.3718667 0.32726667 0.23052500 0.02323678 FALSE TRUE
ENST00000529209 ENSG00000179698 HEK293_OSMI2_2hA HEK293_TMG_2hB WDR97 protein_coding retained_intron 0.2333291 0.1254603 0.3445566 0.01297224 0.01946764 1.388146 0.13055011 0.075977168 0.1911430 0.004280546 0.008418417 1.226196 0.5723792 0.6122 0.5563333 -0.05586667 0.96308888 0.02323678 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000179698 E001 0.0000000       8 144107726 144107738 13 +      
ENSG00000179698 E002 0.1472490 0.043062091 1.00000000   8 144107739 144107862 124 + 0.083 0.000 -9.989
ENSG00000179698 E003 0.0000000       8 144108059 144108195 137 +      
ENSG00000179698 E004 0.0000000       8 144108316 144108944 629 +      
ENSG00000179698 E005 0.0000000       8 144109049 144109170 122 +      
ENSG00000179698 E006 0.2924217 0.029078516 0.62440182   8 144109335 144109698 364 + 0.152 0.000 -12.782
ENSG00000179698 E007 0.1472490 0.043062091 1.00000000   8 144109699 144109726 28 + 0.083 0.000 -12.034
ENSG00000179698 E008 0.4375944 0.024174473 0.36861756 0.51302888 8 144109727 144110034 308 + 0.212 0.000 -13.191
ENSG00000179698 E009 0.0000000       8 144110035 144110113 79 +      
ENSG00000179698 E010 0.2924217 0.029078516 0.62440182   8 144110114 144110256 143 + 0.152 0.000 -12.782
ENSG00000179698 E011 0.1472490 0.043062091 1.00000000   8 144110257 144110340 84 + 0.083 0.000 -12.034
ENSG00000179698 E012 0.9578041 0.013339394 0.54159334 0.67255670 8 144110341 144110577 237 + 0.311 0.178 -1.049
ENSG00000179698 E013 0.5202097 0.022653021 0.81109498 0.88017179 8 144110578 144110648 71 + 0.152 0.178 0.274
ENSG00000179698 E014 0.6717251 0.062631080 0.92899225 0.95935065 8 144110649 144110739 91 + 0.212 0.178 -0.308
ENSG00000179698 E015 0.7394793 0.016013094 0.70980420 0.80709372 8 144110740 144110863 124 + 0.264 0.178 -0.730
ENSG00000179698 E016 0.4396707 0.022898579 0.36924756 0.51367761 8 144110864 144110891 28 + 0.212 0.000 -13.192
ENSG00000179698 E017 0.7341808 0.043465567 0.55129176 0.68078488 8 144110892 144110996 105 + 0.212 0.302 0.680
ENSG00000179698 E018 0.4375944 0.024174473 0.36861756 0.51302888 8 144110997 144111100 104 + 0.212 0.000 -13.191
ENSG00000179698 E019 0.7331366 0.017235252 0.71248710 0.80921418 8 144111101 144111222 122 + 0.264 0.178 -0.730
ENSG00000179698 E020 1.2554226 0.012532005 0.88394860 0.92979362 8 144111223 144111425 203 + 0.353 0.303 -0.313
ENSG00000179698 E021 1.9165385 0.011040647 0.86106904 0.91440409 8 144111426 144111486 61 + 0.460 0.401 -0.312
ENSG00000179698 E022 1.8445324 0.008163662 0.38173492 0.52604480 8 144111487 144111631 145 + 0.491 0.303 -1.050
ENSG00000179698 E023 1.2608349 0.011241777 0.30827468 0.45054012 8 144111632 144111781 150 + 0.392 0.178 -1.535
ENSG00000179698 E024 1.8583889 0.222544072 0.88666790 0.93152127 8 144111887 144112144 258 + 0.461 0.399 -0.329
ENSG00000179698 E025 1.3232786 0.011333633 0.03156506 0.07500384 8 144112224 144112349 126 + 0.460 0.000 -14.262
ENSG00000179698 E026 0.7331366 0.017235252 0.71248710 0.80921418 8 144112447 144112468 22 + 0.264 0.178 -0.730
ENSG00000179698 E027 1.0255583 0.014397265 0.41371053 0.55712014 8 144112469 144112530 62 + 0.353 0.178 -1.314
ENSG00000179698 E028 6.0677772 0.009059164 0.30593824 0.44807948 8 144112531 144113439 909 + 0.875 0.703 -0.682
ENSG00000179698 E029 1.6179009 0.009724086 0.85264386 0.90868830 8 144113440 144113517 78 + 0.392 0.401 0.050
ENSG00000179698 E030 2.2725855 0.008563276 0.20943342 0.33785952 8 144113518 144113656 139 + 0.427 0.606 0.857
ENSG00000179698 E031 2.7122562 0.008061408 0.46613955 0.60570070 8 144113657 144113881 225 + 0.519 0.606 0.398
ENSG00000179698 E032 2.2153281 0.007101762 0.49206704 0.62928359 8 144113977 144114162 186 + 0.460 0.547 0.423
ENSG00000179698 E033 2.1819169 0.007243862 0.49272260 0.62986132 8 144114163 144114277 115 + 0.460 0.547 0.422
ENSG00000179698 E034 2.6990166 0.007519318 0.05348661 0.11535739 8 144114278 144114475 198 + 0.427 0.703 1.273
ENSG00000179698 E035 1.4456598 0.010177992 0.69579214 0.79630128 8 144114476 144114553 78 + 0.354 0.401 0.272
ENSG00000179698 E036 1.5135132 0.010094661 0.27334375 0.41235988 8 144114554 144114675 122 + 0.311 0.481 0.951
ENSG00000179698 E037 1.4684633 0.013664326 0.59124435 0.71404100 8 144114749 144114911 163 + 0.427 0.303 -0.730
ENSG00000179698 E038 5.7599979 0.013066531 0.65194201 0.76271333 8 144115341 144115858 518 + 0.795 0.818 0.092
ENSG00000179698 E039 0.4720498 0.027465510 0.81031141 0.87961946 8 144115943 144116013 71 + 0.152 0.178 0.272
ENSG00000179698 E040 6.7213278 0.003148657 0.43292135 0.57537077 8 144116091 144118328 2238 + 0.850 0.907 0.220