ENSG00000179152

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000383746 ENSG00000179152 HEK293_OSMI2_2hA HEK293_TMG_2hB TCAIM protein_coding protein_coding 15.62539 8.361994 23.01856 1.002028 0.327953 1.459781 4.2168026 3.5670450 4.6800563 0.7837307 0.12761785 0.3908370 0.29565417 0.41820000 0.20333333 -0.21486667 1.772326e-04 1.032945e-15   FALSE
ENST00000412611 ENSG00000179152 HEK293_OSMI2_2hA HEK293_TMG_2hB TCAIM protein_coding nonsense_mediated_decay 15.62539 8.361994 23.01856 1.002028 0.327953 1.459781 1.1120347 0.9298456 0.8643734 0.7187654 0.86437339 -0.1041743 0.09056667 0.10960000 0.03843333 -0.07116667 5.216139e-01 1.032945e-15 FALSE TRUE
ENST00000417237 ENSG00000179152 HEK293_OSMI2_2hA HEK293_TMG_2hB TCAIM protein_coding protein_coding 15.62539 8.361994 23.01856 1.002028 0.327953 1.459781 5.4120539 1.6653341 8.5695856 0.2691618 1.14102817 2.3564592 0.30884583 0.20966667 0.37110000 0.16143333 1.671980e-01 1.032945e-15 FALSE TRUE
ENST00000417768 ENSG00000179152 HEK293_OSMI2_2hA HEK293_TMG_2hB TCAIM protein_coding nonsense_mediated_decay 15.62539 8.361994 23.01856 1.002028 0.327953 1.459781 1.7182382 0.0000000 3.6910626 0.0000000 0.55319061 8.5317957 0.07465833 0.00000000 0.15976667 0.15976667 1.032945e-15 1.032945e-15 FALSE FALSE
ENST00000444602 ENSG00000179152 HEK293_OSMI2_2hA HEK293_TMG_2hB TCAIM protein_coding protein_coding 15.62539 8.361994 23.01856 1.002028 0.327953 1.459781 0.7757548 0.7138137 0.9689357 0.1014243 0.03498314 0.4355957 0.05891667 0.08836667 0.04213333 -0.04623333 3.876008e-02 1.032945e-15 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000179152 E001 0.0000000       3 44337952 44338017 66 +      
ENSG00000179152 E002 0.7019140 0.0172202675 3.164977e-01 4.592770e-01 3 44338018 44338118 101 + 0.137 0.331 1.619
ENSG00000179152 E003 0.8534295 0.0192370234 5.092236e-01 6.445579e-01 3 44338119 44338121 3 + 0.192 0.331 1.034
ENSG00000179152 E004 86.1879846 0.0004921335 5.195181e-01 6.536012e-01 3 44338122 44338319 198 + 1.892 1.904 0.043
ENSG00000179152 E005 4.5261869 0.0516689324 8.546907e-01 9.101124e-01 3 44338452 44338751 300 + 0.691 0.744 0.218
ENSG00000179152 E006 2.1926398 0.1037658050 4.904444e-01 6.277835e-01 3 44338752 44338756 5 + 0.427 0.583 0.754
ENSG00000179152 E007 2.3504979 0.2295623487 5.369782e-01 6.686445e-01 3 44338757 44338759 3 + 0.458 0.581 0.586
ENSG00000179152 E008 2.1989825 0.1891962644 4.776314e-01 6.161534e-01 3 44338760 44338765 6 + 0.428 0.581 0.743
ENSG00000179152 E009 2.6429196 0.0871927875 7.742748e-01 8.544834e-01 3 44338766 44338775 10 + 0.510 0.583 0.340
ENSG00000179152 E010 3.6758648 0.0260755070 7.888457e-01 8.648399e-01 3 44338776 44338782 7 + 0.619 0.696 0.328
ENSG00000179152 E011 6.6651276 0.0028805924 3.754891e-01 5.199187e-01 3 44338783 44338805 23 + 0.805 0.953 0.565
ENSG00000179152 E012 10.5932549 0.0015994025 5.768018e-01 7.021717e-01 3 44338806 44338834 29 + 0.996 1.093 0.354
ENSG00000179152 E013 3.6398964 0.0094156527 3.816238e-01 5.259300e-01 3 44339687 44341425 1739 + 0.578 0.745 0.711
ENSG00000179152 E014 78.5741887 0.0013010746 8.468632e-02 1.668945e-01 3 44354739 44354811 73 + 1.868 1.827 -0.140
ENSG00000179152 E015 97.9569449 0.0021770024 8.169194e-01 8.841777e-01 3 44357741 44357876 136 + 1.943 1.972 0.097
ENSG00000179152 E016 37.6942601 0.0200439619 7.005070e-02 1.434521e-01 3 44358217 44358345 129 + 1.477 1.690 0.727
ENSG00000179152 E017 88.2310151 0.0160677700 1.253296e-05 8.142983e-05 3 44358346 44359110 765 + 1.780 2.127 1.166
ENSG00000179152 E018 104.2317683 0.0154906561 4.133124e-14 1.241097e-12 3 44359111 44359804 694 + 1.741 2.296 1.864
ENSG00000179152 E019 81.3783257 0.0116115131 7.118020e-02 1.452975e-01 3 44361365 44361518 154 + 1.893 1.806 -0.290
ENSG00000179152 E020 16.3887478 0.0011669775 3.969245e-04 1.762602e-03 3 44362420 44363037 618 + 1.078 1.416 1.193
ENSG00000179152 E021 26.8740475 0.0007313609 7.691370e-02 1.545608e-01 3 44367456 44367531 76 + 1.429 1.333 -0.332
ENSG00000179152 E022 83.3969053 0.0057672900 1.215231e-03 4.692181e-03 3 44367532 44367708 177 + 1.917 1.769 -0.498
ENSG00000179152 E023 1.2909221 0.0102564361 1.599856e-01 2.751019e-01 3 44367709 44367879 171 + 0.241 0.516 1.617
ENSG00000179152 E024 0.4439371 0.0215676682 4.001259e-01 5.438482e-01 3 44391208 44391331 124 + 0.192 0.001 -8.847
ENSG00000179152 E025 63.8938250 0.0004017433 7.787169e-06 5.303814e-05 3 44392855 44392977 123 + 1.812 1.618 -0.659
ENSG00000179152 E026 47.9380396 0.0005059337 1.401109e-05 8.997521e-05 3 44396400 44396497 98 + 1.696 1.470 -0.772
ENSG00000179152 E027 43.7721660 0.0005927976 2.232238e-05 1.368623e-04 3 44396743 44396786 44 + 1.659 1.426 -0.797
ENSG00000179152 E028 48.8164372 0.0005111247 1.791895e-06 1.408410e-05 3 44396787 44396834 48 + 1.707 1.453 -0.869
ENSG00000179152 E029 75.7495409 0.0079627499 4.044862e-03 1.326720e-02 3 44400355 44400521 167 + 1.874 1.726 -0.499
ENSG00000179152 E030 51.7267635 0.0158463467 1.730843e-01 2.921969e-01 3 44400522 44400587 66 + 1.695 1.616 -0.267
ENSG00000179152 E031 2.2927360 0.0064286342 2.240488e-01 3.552508e-01 3 44400588 44401202 615 + 0.533 0.330 -1.083
ENSG00000179152 E032 72.3213027 0.0006355341 1.592764e-02 4.256996e-02 3 44401203 44401334 132 + 1.839 1.764 -0.254
ENSG00000179152 E033 357.5102420 0.0003232839 7.837165e-01 8.612277e-01 3 44407442 44409451 2010 + 2.499 2.534 0.117