ENSG00000175787

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000340911 ENSG00000175787 HEK293_OSMI2_2hA HEK293_TMG_2hB ZNF169 protein_coding protein_coding 3.079437 2.13148 3.10459 0.1887415 0.5698215 0.5404342 0.3706198 0.1061725 0.4942740 0.03328058 0.10199134 2.1179387 0.1241333 0.0511000 0.15933333 0.10823333 0.03015857 0.03015857 FALSE TRUE
ENST00000395395 ENSG00000175787 HEK293_OSMI2_2hA HEK293_TMG_2hB ZNF169 protein_coding protein_coding 3.079437 2.13148 3.10459 0.1887415 0.5698215 0.5404342 1.0722071 1.0103749 1.2972805 0.09914569 0.02457973 0.3574695 0.3887000 0.4810667 0.44143333 -0.03963333 0.86881341 0.03015857 FALSE TRUE
ENST00000480716 ENSG00000175787 HEK293_OSMI2_2hA HEK293_TMG_2hB ZNF169 protein_coding protein_coding 3.079437 2.13148 3.10459 0.1887415 0.5698215 0.5404342 0.4040514 0.4177652 0.3016447 0.04949101 0.06770670 -0.4569172 0.1376375 0.1968667 0.09676667 -0.10010000 0.06625138 0.03015857 FALSE FALSE
ENST00000481550 ENSG00000175787 HEK293_OSMI2_2hA HEK293_TMG_2hB ZNF169 protein_coding protein_coding 3.079437 2.13148 3.10459 0.1887415 0.5698215 0.5404342 0.4498903 0.2027554 0.2348713 0.04115797 0.05075407 0.2028282 0.1440042 0.0931000 0.08010000 -0.01300000 0.80651223 0.03015857 FALSE FALSE
ENST00000492115 ENSG00000175787 HEK293_OSMI2_2hA HEK293_TMG_2hB ZNF169 protein_coding retained_intron 3.079437 2.13148 3.10459 0.1887415 0.5698215 0.5404342 0.4873946 0.2742377 0.4609169 0.17631972 0.17674528 0.7283749 0.1325250 0.1263333 0.13870000 0.01236667 0.84351365 0.03015857   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000175787 E001 0.000000       9 94259298 94259304 7 +      
ENSG00000175787 E002 0.953449 0.3630262230 0.84677329 0.90478147 9 94259305 94259312 8 + 0.289 0.300 0.076
ENSG00000175787 E003 1.398430 0.0109441865 0.80465915 0.87571058 9 94259313 94259320 8 + 0.411 0.369 -0.236
ENSG00000175787 E004 2.066933 0.0073563228 0.86213461 0.91511888 9 94259321 94259327 7 + 0.506 0.479 -0.135
ENSG00000175787 E005 5.194835 0.0545605412 0.80618386 0.87680348 9 94259328 94259345 18 + 0.782 0.821 0.153
ENSG00000175787 E006 11.733420 0.0016392642 0.46832757 0.60774346 9 94278758 94278845 88 + 1.069 1.138 0.248
ENSG00000175787 E007 13.621633 0.0273403507 0.66595418 0.77351246 9 94292341 94292467 127 + 1.145 1.178 0.119
ENSG00000175787 E008 1.515590 0.0092655255 0.81167593 0.88048448 9 94292468 94292623 156 + 0.411 0.370 -0.233
ENSG00000175787 E009 13.453897 0.0015167634 0.63615986 0.75025138 9 94292974 94293069 96 + 1.144 1.188 0.155
ENSG00000175787 E010 4.907887 0.0036278158 0.87548565 0.92403632 9 94293070 94293441 372 + 0.759 0.780 0.088
ENSG00000175787 E011 24.306725 0.0008721813 0.01243773 0.03458878 9 94293442 94295182 1741 + 1.313 1.479 0.575
ENSG00000175787 E012 11.308534 0.0118360648 0.02115233 0.05391879 9 94295183 94295632 450 + 0.949 1.195 0.894
ENSG00000175787 E013 5.271305 0.0033787337 0.01178894 0.03302790 9 94295633 94295846 214 + 0.584 0.923 1.377
ENSG00000175787 E014 5.811584 0.0029300551 0.03335259 0.07848739 9 94299448 94299814 367 + 0.964 0.701 -1.029
ENSG00000175787 E015 42.401123 0.0006363068 0.12868102 0.23232189 9 94299815 94300800 986 + 1.679 1.608 -0.240
ENSG00000175787 E016 16.059202 0.0140381141 0.31594003 0.45871378 9 94300801 94300968 168 + 1.285 1.194 -0.321
ENSG00000175787 E017 40.326733 0.0006484417 0.02797120 0.06795495 9 94300969 94301829 861 + 1.676 1.570 -0.359
ENSG00000175787 E018 0.000000       9 94314861 94314934 74 +