ENSG00000175643

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-2 / 2
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000312499	ENSG00000175643	HEK293_OSMI2_2hA	HEK293_TMG_2hB	RMI2	protein_coding	protein_coding	31.09839	43.7021	21.80022	2.444774	0.5291542	-1.003028	16.12891	17.40152	15.315053	2.130537	0.3017338	-0.1841499	0.5412208	0.4009	0.7031667	0.3022667	0.0001575177	0.0001575177	FALSE	TRUE
ENST00000576027	ENSG00000175643	HEK293_OSMI2_2hA	HEK293_TMG_2hB	RMI2	protein_coding	protein_coding	31.09839	43.7021	21.80022	2.444774	0.5291542	-1.003028	14.75280	26.06121	6.356168	3.432648	0.5159389	-2.0339603	0.4516375	0.5934	0.2910333	-0.3023667	0.0001698650	0.0001575177		FALSE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

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groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000175643	E001	0.0000000				16	11249619	11249626	8	+
ENSG00000175643	E002	0.0000000				16	11249627	11249648	22	+
ENSG00000175643	E003	0.0000000				16	11249649	11249778	130	+
ENSG00000175643	E004	0.0000000				16	11295216	11295294	79	+
ENSG00000175643	E005	0.0000000				16	11312829	11312899	71	+
ENSG00000175643	E006	0.0000000				16	11312900	11312937	38	+
ENSG00000175643	E007	0.0000000				16	11316141	11316451	311	+
ENSG00000175643	E008	0.0000000				16	11316452	11316884	433	+
ENSG00000175643	E009	0.1482932	0.040962210	9.259894e-01		16	11316885	11317036	152	+	0.000	0.113	8.013
ENSG00000175643	E010	8.9130262	0.003997824	4.469523e-10	7.066159e-09	16	11345450	11345458	9	+	1.211	0.714	-1.871
ENSG00000175643	E011	17.1462430	0.022575510	1.574976e-09	2.251883e-08	16	11345459	11345469	11	+	1.458	1.012	-1.579
ENSG00000175643	E012	30.6822384	0.044834111	3.269820e-09	4.405189e-08	16	11345470	11345543	74	+	1.714	1.218	-1.710
ENSG00000175643	E013	109.8924277	0.006400435	1.520616e-07	1.491232e-06	16	11345544	11345766	223	+	2.061	2.021	-0.134
ENSG00000175643	E014	1040.8963229	0.014925287	5.710700e-12	1.236853e-10	16	11350642	11351760	1119	+	2.819	3.107	0.960
ENSG00000175643	E015	0.8396112	0.689535566	7.994992e-01	8.720956e-01	16	11379822	11379887	66	+	0.233	0.280	0.353
ENSG00000175643	E016	5.6273020	0.016856627	7.889273e-01	8.648900e-01	16	11380798	11381662	865	+	0.721	0.862	0.560

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000175643

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3