ENSG00000173402

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000308775 ENSG00000173402 HEK293_OSMI2_2hA HEK293_TMG_2hB DAG1 protein_coding protein_coding 61.30384 66.10316 47.61042 3.605164 0.5502848 -0.4733573 35.771396 27.738840 36.0247438 6.9428162 0.9431708 0.3769611 0.58552500 0.4108333 0.75713333 0.3463 2.815956e-03 1.922558e-22 FALSE TRUE
ENST00000421560 ENSG00000173402 HEK293_OSMI2_2hA HEK293_TMG_2hB DAG1 protein_coding protein_coding 61.30384 66.10316 47.61042 3.605164 0.5502848 -0.4733573 3.389484 2.683225 3.5694240 0.8003486 1.0164313 0.4103925 0.05549583 0.0400000 0.07460000 0.0346 4.457031e-01 1.922558e-22 FALSE TRUE
ENST00000431960 ENSG00000173402 HEK293_OSMI2_2hA HEK293_TMG_2hB DAG1 protein_coding protein_coding 61.30384 66.10316 47.61042 3.605164 0.5502848 -0.4733573 9.614883 9.477428 0.6933409 0.9824043 0.6038040 -3.7537210 0.15713750 0.1458667 0.01426667 -0.1316 3.913893e-02 1.922558e-22 FALSE TRUE
ENST00000461492 ENSG00000173402 HEK293_OSMI2_2hA HEK293_TMG_2hB DAG1 protein_coding processed_transcript 61.30384 66.10316 47.61042 3.605164 0.5502848 -0.4733573 6.269344 20.794191 0.0000000 3.4411459 0.0000000 -11.0226584 0.09758333 0.3215000 0.00000000 -0.3215 1.922558e-22 1.922558e-22 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

No results under this category.

Splicing

All exons whithin this gene region are shown and numbering below.

No results under this category.

Transcripts

All isoforms whithin this gene region are shown below.

No results under this category.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000173402 E001 0.0000000       3 49468703 49468712 10 +      
ENSG00000173402 E002 0.1515154 0.042786939 3.392762e-01   3 49468713 49469055 343 +      
ENSG00000173402 E003 0.4482035 0.029057140 4.041917e-02 9.178983e-02 3 49470132 49470135 4 +      
ENSG00000173402 E004 12.0922856 0.006145132 3.059814e-07 2.825741e-06 3 49470136 49470246 111 +      
ENSG00000173402 E005 10.4607662 0.001688957 7.907295e-06 5.377125e-05 3 49470247 49470266 20 +      
ENSG00000173402 E006 9.1904681 0.001792147 5.157230e-05 2.895823e-04 3 49470267 49470274 8 +      
ENSG00000173402 E007 3.1891405 0.016024159 2.871692e-03 9.888280e-03 3 49470275 49470276 2 +      
ENSG00000173402 E008 4.0017719 0.011511993 5.578947e-04 2.377119e-03 3 49470277 49470278 2 +      
ENSG00000173402 E009 7.5277287 0.002206490 5.279555e-04 2.264218e-03 3 49470279 49470288 10 +      
ENSG00000173402 E010 10.0637790 0.002822589 7.527267e-05 4.055451e-04 3 49470289 49470295 7 +      
ENSG00000173402 E011 11.7653419 0.001732508 2.161205e-06 1.668162e-05 3 49470296 49470299 4 +      
ENSG00000173402 E012 14.6234788 0.023044457 1.048908e-05 6.940948e-05 3 49470300 49470301 2 +      
ENSG00000173402 E013 17.4841420 0.019887093 5.392089e-06 3.809776e-05 3 49470302 49470305 4 +      
ENSG00000173402 E014 20.1111525 0.021884870 1.342737e-05 8.657894e-05 3 49470306 49470318 13 +      
ENSG00000173402 E015 46.7009376 0.013647622 6.859308e-05 3.733481e-04 3 49470319 49470353 35 +      
ENSG00000173402 E016 104.6521628 0.010416394 2.031079e-06 1.577839e-05 3 49470354 49470433 80 +      
ENSG00000173402 E017 5.1640955 0.004057128 1.025189e-04 5.336860e-04 3 49470434 49470573 140 +      
ENSG00000173402 E018 7.8899388 0.024379460 9.994013e-03 2.874789e-02 3 49470666 49470889 224 +      
ENSG00000173402 E019 5.2985573 0.003318283 8.615304e-04 3.478937e-03 3 49470965 49471049 85 +      
ENSG00000173402 E020 14.5408471 0.018884099 1.355771e-01 2.419157e-01 3 49476849 49476900 52 +      
ENSG00000173402 E021 5.8917274 0.002874039 1.428928e-01 2.519765e-01 3 49476901 49476905 5 +      
ENSG00000173402 E022 0.7675920 0.015850722 3.847112e-01 5.288632e-01 3 49487228 49487253 26 +      
ENSG00000173402 E023 8.4594001 0.002844311 4.393832e-01 5.811335e-01 3 49487254 49487415 162 +      
ENSG00000173402 E024 7.2236707 0.083238673 9.095767e-01 9.465474e-01 3 49488626 49488697 72 +      
ENSG00000173402 E025 7.2527178 0.003029329 4.318869e-01 5.743814e-01 3 49488698 49488745 48 +      
ENSG00000173402 E026 0.0000000       3 49492716 49492822 107 +      
ENSG00000173402 E027 1.6930406 0.221609750 6.172822e-01 7.351253e-01 3 49492823 49492826 4 +      
ENSG00000173402 E028 5.5893196 0.053701211 1.888003e-02 4.907073e-02 3 49492827 49492973 147 +      
ENSG00000173402 E029 2.4734187 0.006313461 3.222081e-01 4.655133e-01 3 49510224 49510418 195 +      
ENSG00000173402 E030 119.4181332 0.007568622 1.438573e-05 9.212513e-05 3 49510419 49510455 37 +      
ENSG00000173402 E031 534.6318276 0.006211765 6.930461e-10 1.059775e-08 3 49510456 49510819 364 +      
ENSG00000173402 E032 7783.3638793 0.008984628 5.201155e-11 9.630957e-10 3 49530797 49535618 4822 +