ENSG00000173273

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-3 / 3
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000310430	ENSG00000173273	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TNKS	protein_coding	protein_coding	6.280512	3.82354	6.551972	0.2982168	0.1206737	0.7754523	4.2765779	1.452261	5.4457073	0.1587807	0.08656162	1.899565	0.6329542	0.3865667	0.83223333	0.44566667	1.566230e-06	9.105418e-09	FALSE	TRUE
ENST00000517770	ENSG00000173273	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TNKS	protein_coding	protein_coding	6.280512	3.82354	6.551972	0.2982168	0.1206737	0.7754523	1.3983727	2.220754	0.3726008	0.3913140	0.16843209	-2.543620	0.2856208	0.5751000	0.05596667	-0.51913333	7.763157e-05	9.105418e-09		FALSE
MSTRG.31097.5	ENSG00000173273	HEK293_OSMI2_2hA	HEK293_TMG_2hB	TNKS	protein_coding		6.280512	3.82354	6.551972	0.2982168	0.1206737	0.7754523	0.4759841	0.000000	0.6018045	0.0000000	0.01236645	5.934999	0.0583625	0.0000000	0.09186667	0.09186667	9.105418e-09	9.105418e-09	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 52
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groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000173273	E001	0.1472490	0.0433362478	1.000000e+00		8	9555775	9555911	137	+	0.072	0.000	-12.027
ENSG00000173273	E002	0.1472490	0.0433362478	1.000000e+00		8	9555912	9555913	2	+	0.072	0.000	-14.387
ENSG00000173273	E003	2.2673782	0.1450511293	1.949139e-01	3.198845e-01	8	9555914	9555931	18	+	0.525	0.336	-1.008
ENSG00000173273	E004	22.4125165	0.0024874176	6.912526e-03	2.099827e-02	8	9555932	9556236	305	+	1.337	1.281	-0.196
ENSG00000173273	E005	38.1813227	0.0225955462	5.491048e-04	2.343555e-03	8	9556237	9556612	376	+	1.585	1.424	-0.551
ENSG00000173273	E006	0.1451727	0.0433661421	1.000000e+00		8	9556613	9558831	2219	+	0.072	0.000	-14.386
ENSG00000173273	E007	0.1482932	0.0412483031	2.284845e-01		8	9566260	9566526	267	+	0.000	0.199	15.940
ENSG00000173273	E008	0.0000000				8	9575007	9575399	393	+
ENSG00000173273	E009	34.1456294	0.0785212509	7.576827e-02	1.527289e-01	8	9580159	9580383	225	+	1.516	1.458	-0.200
ENSG00000173273	E010	0.1515154	0.0431907214	1.000000e+00		8	9615290	9615486	197	+	0.073	0.000	-14.388
ENSG00000173273	E011	27.6960455	0.0007288717	6.765142e-05	3.687842e-04	8	9615582	9615677	96	+	1.445	1.318	-0.440
ENSG00000173273	E012	0.0000000				8	9670119	9670196	78	+
ENSG00000173273	E013	0.0000000				8	9670727	9670789	63	+
ENSG00000173273	E014	0.0000000				8	9670980	9671056	77	+
ENSG00000173273	E015	0.0000000				8	9671146	9671203	58	+
ENSG00000173273	E016	0.0000000				8	9679754	9679836	83	+
ENSG00000173273	E017	0.0000000				8	9679846	9679950	105	+
ENSG00000173273	E018	18.1851131	0.0010040429	1.164228e-05	7.620478e-05	8	9679951	9679987	37	+	1.291	1.038	-0.903
ENSG00000173273	E019	23.6759523	0.0008452924	1.213990e-08	1.474274e-07	8	9680725	9680800	76	+	1.413	1.082	-1.168
ENSG00000173273	E020	0.0000000				8	9680801	9681156	356	+
ENSG00000173273	E021	25.5772852	0.0066213880	4.138523e-05	2.377075e-04	8	9704663	9704757	95	+	1.422	1.224	-0.690
ENSG00000173273	E022	14.0711177	0.0098889057	1.691723e-01	2.871024e-01	8	9706187	9706253	67	+	1.125	1.142	0.058
ENSG00000173273	E023	25.4458738	0.0055468138	2.061764e-02	5.278311e-02	8	9706811	9706997	187	+	1.378	1.354	-0.082
ENSG00000173273	E024	0.0000000				8	9706998	9707008	11	+
ENSG00000173273	E025	20.0096938	0.0009711937	3.200224e-03	1.085654e-02	8	9708371	9708492	122	+	1.295	1.208	-0.304
ENSG00000173273	E026	18.1327307	0.0010257110	9.458824e-02	1.822620e-01	8	9709955	9710046	92	+	1.230	1.253	0.081
ENSG00000173273	E027	15.9155593	0.0011923414	5.919373e-01	7.145838e-01	8	9710142	9710220	79	+	1.149	1.267	0.419
ENSG00000173273	E028	0.7363694	0.0408184664	8.374793e-02	1.654152e-01	8	9710221	9710409	189	+	0.073	0.440	3.272
ENSG00000173273	E029	16.3613278	0.0010808338	1.132279e-02	3.193635e-02	8	9720374	9720455	82	+	1.211	1.141	-0.251
ENSG00000173273	E030	24.1304418	0.0007547859	7.125649e-04	2.943595e-03	8	9720456	9720545	90	+	1.378	1.280	-0.341
ENSG00000173273	E031	0.0000000				8	9722398	9722500	103	+
ENSG00000173273	E032	20.6754695	0.0008964845	1.306049e-03	4.996910e-03	8	9726641	9726720	80	+	1.314	1.208	-0.372
ENSG00000173273	E033	26.3589984	0.0134840919	1.897999e-03	6.908037e-03	8	9730890	9731035	146	+	1.419	1.293	-0.438
ENSG00000173273	E034	28.7236725	0.0243642453	8.808352e-02	1.722130e-01	8	9733279	9733444	166	+	1.426	1.410	-0.054
ENSG00000173273	E035	28.1570046	0.0007143690	5.491144e-04	2.343555e-03	8	9734865	9734990	126	+	1.437	1.354	-0.288
ENSG00000173273	E036	24.5736841	0.0007962060	1.615188e-03	6.008925e-03	8	9734991	9735084	94	+	1.381	1.306	-0.262
ENSG00000173273	E037	28.2952493	0.0030394320	2.472085e-02	6.130362e-02	8	9735377	9735486	110	+	1.416	1.417	0.002
ENSG00000173273	E038	0.0000000				8	9740914	9741115	202	+
ENSG00000173273	E039	0.0000000				8	9743464	9743572	109	+
ENSG00000173273	E040	33.8417632	0.0107995821	2.456388e-03	8.633200e-03	8	9748024	9748212	189	+	1.513	1.428	-0.295
ENSG00000173273	E041	0.4815130	0.0203851297	2.228258e-01	3.537431e-01	8	9748213	9748213	1	+	0.073	0.335	2.681
ENSG00000173273	E042	45.2082492	0.0305861533	3.583414e-02	8.326284e-02	8	9751609	9751846	238	+	1.625	1.591	-0.115
ENSG00000173273	E043	34.2932264	0.0005823996	7.257873e-04	2.991811e-03	8	9752544	9752626	83	+	1.513	1.462	-0.176
ENSG00000173273	E044	36.9736939	0.0006837607	3.513138e-03	1.176388e-02	8	9761516	9761636	121	+	1.532	1.519	-0.044
ENSG00000173273	E045	37.7219531	0.0210980999	2.446410e-01	3.796311e-01	8	9763147	9763244	98	+	1.519	1.581	0.214
ENSG00000173273	E046	31.4598007	0.0172379953	2.395335e-01	3.735688e-01	8	9764716	9764790	75	+	1.443	1.506	0.218
ENSG00000173273	E047	34.1929227	0.0005958781	1.126427e-01	2.094068e-01	8	9765692	9765797	106	+	1.478	1.549	0.243
ENSG00000173273	E048	43.9539867	0.0485564341	1.922262e-01	3.165492e-01	8	9766239	9766425	187	+	1.595	1.619	0.082
ENSG00000173273	E049	17.0516695	0.0230228288	5.474313e-01	6.774882e-01	8	9770106	9770130	25	+	1.176	1.271	0.337
ENSG00000173273	E050	35.5582558	0.0006561063	1.047841e-01	1.977805e-01	8	9770131	9770262	132	+	1.499	1.570	0.244
ENSG00000173273	E051	4.7607544	0.0034187380	3.579717e-01	5.023643e-01	8	9772369	9772423	55	+	0.630	0.903	1.097
ENSG00000173273	E052	725.5215538	0.0139862202	1.548060e-11	3.124271e-10	8	9776650	9782346	5697	+	2.668	3.054	1.284

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000173273

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3