ENSG00000167920

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000301665 ENSG00000167920 HEK293_OSMI2_2hA HEK293_TMG_2hB KRT10-AS1 lncRNA lncRNA 11.67504 18.85308 8.445297 0.5195487 0.1854649 -1.157638 8.8640400 14.5389090 6.2496604 0.1570595 0.7830200 -1.216755 0.75778750 0.772666667 0.7375667 -0.03510000 9.537499e-01 1.284943e-12 FALSE  
ENST00000436612 ENSG00000167920 HEK293_OSMI2_2hA HEK293_TMG_2hB KRT10-AS1 lncRNA lncRNA 11.67504 18.85308 8.445297 0.5195487 0.1854649 -1.157638 1.8093414 2.6264561 1.2532663 0.6038651 0.4447760 -1.061441 0.14613750 0.137866667 0.1497000 0.01183333 1.000000e+00 1.284943e-12 FALSE  
ENST00000654043 ENSG00000167920 HEK293_OSMI2_2hA HEK293_TMG_2hB KRT10-AS1 lncRNA lncRNA 11.67504 18.85308 8.445297 0.5195487 0.1854649 -1.157638 0.3846577 1.2491611 0.0000000 0.1265942 0.0000000 -6.976319 0.03257500 0.066000000 0.0000000 -0.06600000 1.284943e-12 1.284943e-12 FALSE  
ENST00000662074 ENSG00000167920 HEK293_OSMI2_2hA HEK293_TMG_2hB KRT10-AS1 lncRNA lncRNA 11.67504 18.85308 8.445297 0.5195487 0.1854649 -1.157638 0.3376252 0.1742253 0.6187106 0.1742253 0.2011758 1.770925 0.03493333 0.009633333 0.0738000 0.06416667 1.116230e-01 1.284943e-12    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000167920 E001 0.8136755 0.0145437250 0.1211657970 0.221600586 17 40818113 40819105 993 + 0.417 0.144 -2.030
ENSG00000167920 E002 0.9985004 0.0126901144 0.7166836292 0.812261455 17 40819106 40819112 7 + 0.317 0.252 -0.446
ENSG00000167920 E003 1.5154878 0.0091429102 0.6570997889 0.766532145 17 40819113 40819121 9 + 0.417 0.339 -0.445
ENSG00000167920 E004 4.7929854 0.1320067336 0.4962502788 0.632944373 17 40819122 40819136 15 + 0.567 0.724 0.676
ENSG00000167920 E005 8.1715744 0.0741471209 0.2613478812 0.398986328 17 40819137 40819144 8 + 0.724 0.929 0.802
ENSG00000167920 E006 81.5487227 0.0017329947 0.9168164830 0.951453353 17 40819145 40819170 26 + 1.840 1.841 0.003
ENSG00000167920 E007 87.2361767 0.0003698473 0.6744816495 0.779969633 17 40819171 40819178 8 + 1.853 1.877 0.080
ENSG00000167920 E008 111.7238180 0.0003296595 0.3186742059 0.461645394 17 40819179 40819197 19 + 2.001 1.970 -0.106
ENSG00000167920 E009 135.1551296 0.0003294680 0.2933724711 0.434414327 17 40819198 40819208 11 + 2.084 2.054 -0.100
ENSG00000167920 E010 4.7198585 0.0040274418 0.0609878640 0.128297591 17 40819209 40819279 71 + 0.417 0.744 1.495
ENSG00000167920 E011 0.9599941 0.0448739663 0.0054517041 0.017159431 17 40828057 40828103 47 + 0.566 0.078 -3.762
ENSG00000167920 E012 2.6979713 0.0064560590 0.1456244047 0.255703503 17 40828104 40828296 193 + 0.678 0.443 -1.082
ENSG00000167920 E013 0.4741261 0.0208859726 0.1518092822 0.264122889 17 40829135 40829796 662 + 0.317 0.078 -2.445
ENSG00000167920 E014 1.2209898 0.0108647759 0.4391177752 0.580896069 17 40833112 40833114 3 + 0.187 0.339 1.139
ENSG00000167920 E015 218.4648404 0.0022689565 0.9055934240 0.943939551 17 40833115 40833199 85 + 2.267 2.267 0.000
ENSG00000167920 E016 294.7588136 0.0003836823 0.4298701626 0.572522905 17 40834382 40834519 138 + 2.379 2.403 0.078
ENSG00000167920 E017 542.5934921 0.0035508166 0.5602355666 0.688244985 17 40834520 40835961 1442 + 2.647 2.668 0.070
ENSG00000167920 E018 13.8930099 0.0014501456 0.0005270299 0.002260812 17 40835962 40836270 309 + 1.331 1.019 -1.109