ENSG00000167861

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000318565 ENSG00000167861 HEK293_OSMI2_2hA HEK293_TMG_2hB HID1 protein_coding protein_coding 7.100512 11.69616 4.747341 0.756092 0.247219 -1.29904 1.3446134 2.9269875 0.5480332 0.04731179 0.03846510 -2.395914 0.17837917 0.2521000 0.1160333 -0.1360667 0.0003324331 0.0003324331 FALSE TRUE
ENST00000425042 ENSG00000167861 HEK293_OSMI2_2hA HEK293_TMG_2hB HID1 protein_coding protein_coding 7.100512 11.69616 4.747341 0.756092 0.247219 -1.29904 4.0020963 6.4118672 3.1880927 0.38157343 0.10882195 -1.005781 0.55596250 0.5486667 0.6770667 0.1284000 0.2096414914 0.0003324331 FALSE TRUE
ENST00000528902 ENSG00000167861 HEK293_OSMI2_2hA HEK293_TMG_2hB HID1 protein_coding retained_intron 7.100512 11.69616 4.747341 0.756092 0.247219 -1.29904 0.3955543 0.6823061 0.2942604 0.07341756 0.03629461 -1.186103 0.05690000 0.0580000 0.0616000 0.0036000 0.9188623459 0.0003324331 TRUE TRUE
MSTRG.15043.2 ENSG00000167861 HEK293_OSMI2_2hA HEK293_TMG_2hB HID1 protein_coding   7.100512 11.69616 4.747341 0.756092 0.247219 -1.29904 0.4041371 0.7275707 0.2417101 0.13988447 0.10804577 -1.551018 0.06487083 0.0612000 0.0489000 -0.0123000 0.8168233077 0.0003324331 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000167861 E001 0.0000000       17 74950742 74950742 1 -      
ENSG00000167861 E002 123.9405245 0.0007945086 0.059841572 0.126344953 17 74950743 74951455 713 - 1.982 2.050 0.226
ENSG00000167861 E003 51.5012671 0.0004912018 0.409504585 0.553115416 17 74951456 74951633 178 - 1.625 1.667 0.145
ENSG00000167861 E004 43.4950554 0.0005479220 0.391199490 0.535131488 17 74951905 74952063 159 - 1.544 1.593 0.167
ENSG00000167861 E005 33.3432298 0.0044544999 0.773025459 0.853505073 17 74952269 74952360 92 - 1.461 1.480 0.065
ENSG00000167861 E006 32.2645092 0.0016297004 0.491809111 0.629062550 17 74953006 74953086 81 - 1.498 1.449 -0.168
ENSG00000167861 E007 29.4097410 0.0078393193 0.400524759 0.544222442 17 74953545 74953651 107 - 1.476 1.408 -0.236
ENSG00000167861 E008 46.4235329 0.0005352111 0.028703059 0.069412477 17 74954138 74954325 188 - 1.697 1.574 -0.417
ENSG00000167861 E009 22.6760604 0.0283405627 0.015004259 0.040497391 17 74954326 74954365 40 - 1.484 1.226 -0.900
ENSG00000167861 E010 1.1897566 0.0177448420 0.452023455 0.592917541 17 74954366 74954437 72 - 0.402 0.264 -0.869
ENSG00000167861 E011 1.5876102 0.0085189789 0.046476359 0.102895954 17 74954438 74954972 535 - 0.607 0.263 -1.870
ENSG00000167861 E012 19.5704947 0.0249407868 0.094189607 0.181684265 17 74955792 74955820 29 - 1.378 1.193 -0.648
ENSG00000167861 E013 37.5847088 0.0006155023 0.059934019 0.126496436 17 74955821 74955956 136 - 1.603 1.486 -0.400
ENSG00000167861 E014 14.8440750 0.0106267621 0.001025413 0.004046101 17 74957969 74958140 172 - 0.819 1.220 1.480
ENSG00000167861 E015 42.0874972 0.0005291769 0.710468204 0.807647492 17 74958141 74958202 62 - 1.557 1.577 0.067
ENSG00000167861 E016 28.0166446 0.0007212978 0.869775895 0.920269493 17 74958203 74958219 17 - 1.396 1.405 0.032
ENSG00000167861 E017 59.8753522 0.0004397793 0.372047679 0.516527794 17 74958327 74958478 152 - 1.755 1.708 -0.158
ENSG00000167861 E018 4.2060577 0.0333091443 0.434327986 0.576710244 17 74958479 74958672 194 - 0.746 0.619 -0.534
ENSG00000167861 E019 52.3187970 0.0005585937 0.647271294 0.758971441 17 74958673 74958763 91 - 1.645 1.667 0.076
ENSG00000167861 E020 0.8481309 0.0143330559 0.610991453 0.730217947 17 74958764 74958791 28 - 0.304 0.211 -0.699
ENSG00000167861 E021 46.7622897 0.0004614468 0.281731995 0.421651644 17 74958911 74958975 65 - 1.569 1.629 0.203
ENSG00000167861 E022 46.2441814 0.0004787366 0.130435151 0.234763940 17 74958976 74959051 76 - 1.544 1.631 0.294
ENSG00000167861 E023 40.2996167 0.0005748124 0.112881165 0.209753495 17 74959881 74959937 57 - 1.476 1.574 0.335
ENSG00000167861 E024 68.0011196 0.0004339155 0.819286596 0.885884465 17 74960026 74960248 223 - 1.770 1.778 0.028
ENSG00000167861 E025 18.5593836 0.0010352726 0.015035385 0.040568687 17 74961597 74961872 276 - 1.048 1.277 0.821
ENSG00000167861 E026 58.3638312 0.0004168888 0.823234043 0.888605890 17 74961873 74961989 117 - 1.701 1.710 0.030
ENSG00000167861 E027 42.9654480 0.0034307169 0.412859263 0.556436561 17 74962234 74962287 54 - 1.538 1.590 0.178
ENSG00000167861 E028 50.5014388 0.0011336774 0.490558099 0.627907871 17 74962288 74962340 53 - 1.674 1.634 -0.138
ENSG00000167861 E029 36.8353222 0.0006210985 0.273252873 0.412258894 17 74962965 74962972 8 - 1.563 1.492 -0.242
ENSG00000167861 E030 41.6337119 0.0007956663 0.069402745 0.142372949 17 74962973 74962986 14 - 1.640 1.531 -0.371
ENSG00000167861 E031 65.4873177 0.0004496161 0.640235526 0.753517511 17 74962987 74963078 92 - 1.774 1.749 -0.084
ENSG00000167861 E032 26.2339689 0.0012110469 0.903166663 0.942397355 17 74963079 74963081 3 - 1.387 1.375 -0.040
ENSG00000167861 E033 6.5893882 0.0025857316 0.002445544 0.008599234 17 74963082 74963507 426 - 1.067 0.696 -1.428
ENSG00000167861 E034 2.3155737 0.0800145103 0.153468169 0.266374294 17 74963508 74963739 232 - 0.659 0.392 -1.277
ENSG00000167861 E035 33.0104792 0.0006740455 0.946613297 0.970492770 17 74963740 74963770 31 - 1.469 1.471 0.007
ENSG00000167861 E036 71.2472052 0.0004477006 0.263771769 0.401691067 17 74963771 74963910 140 - 1.755 1.805 0.169
ENSG00000167861 E037 0.7029582 0.0165929202 0.862076649 0.915101882 17 74963911 74964482 572 - 0.179 0.211 0.298
ENSG00000167861 E038 80.0087149 0.0023801095 0.418978695 0.562240175 17 74964483 74964632 150 - 1.816 1.854 0.128
ENSG00000167861 E039 1.0673860 0.0133625712 0.831597701 0.894463752 17 74967806 74967933 128 - 0.304 0.264 -0.282
ENSG00000167861 E040 52.0544189 0.0036694664 0.897064732 0.938263233 17 74972591 74972771 181 - 1.669 1.660 -0.031
ENSG00000167861 E041 0.0000000       17 74972838 74973038 201 -      
ENSG00000167861 E042 0.0000000       17 74973039 74973166 128 -