ENSG00000167747

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000596655 ENSG00000167747 HEK293_OSMI2_2hA HEK293_TMG_2hB C19orf48 transcribed_unitary_pseudogene retained_intron 305.6639 551.836 165.8892 22.88761 6.595448 -1.733959 35.41063 43.98246 22.361783 3.676487 0.5897210 -0.9755762 0.13264167 0.07950000 0.13493333 0.05543333 1.265216e-08 1.265216e-08 FALSE  
ENST00000598463 ENSG00000167747 HEK293_OSMI2_2hA HEK293_TMG_2hB C19orf48 transcribed_unitary_pseudogene processed_transcript 305.6639 551.836 165.8892 22.88761 6.595448 -1.733959 13.41856 16.06017 10.527137 0.408426 1.2172983 -0.6089024 0.05419583 0.02920000 0.06386667 0.03466667 5.232213e-04 1.265216e-08 FALSE  
ENST00000641539 ENSG00000167747 HEK293_OSMI2_2hA HEK293_TMG_2hB C19orf48 transcribed_unitary_pseudogene transcribed_unitary_pseudogene 305.6639 551.836 165.8892 22.88761 6.595448 -1.733959 27.09337 54.23571 13.414262 9.763783 2.9399229 -2.0146663 0.08430833 0.09816667 0.08066667 -0.01750000 7.974293e-01 1.265216e-08    
ENST00000641834 ENSG00000167747 HEK293_OSMI2_2hA HEK293_TMG_2hB C19orf48 transcribed_unitary_pseudogene processed_transcript 305.6639 551.836 165.8892 22.88761 6.595448 -1.733959 176.05511 340.02110 88.907540 12.491720 3.5448478 -1.9351268 0.55030833 0.61656667 0.53626667 -0.08030000 1.417437e-02 1.265216e-08 FALSE  
ENST00000693315 ENSG00000167747 HEK293_OSMI2_2hA HEK293_TMG_2hB C19orf48 transcribed_unitary_pseudogene processed_transcript 305.6639 551.836 165.8892 22.88761 6.595448 -1.733959 15.66045 28.77149 7.676088 2.403859 0.9744537 -1.9048199 0.05025833 0.05216667 0.04606667 -0.00610000 7.479833e-01 1.265216e-08 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000167747 E001 9.499071 1.082490e-02 3.051670e-01 4.472105e-01 19 50797687 50797689 3 - 1.019 0.897 -0.456
ENSG00000167747 E002 13.975097 1.837675e-02 6.444390e-01 7.567492e-01 19 50797690 50797703 14 - 1.019 1.087 0.247
ENSG00000167747 E003 937.927332 2.299100e-03 2.985023e-06 2.234663e-05 19 50797704 50797760 57 - 2.738 2.882 0.479
ENSG00000167747 E004 6336.374552 1.111124e-03 1.291744e-02 3.572042e-02 19 50797761 50798193 433 - 3.647 3.697 0.163
ENSG00000167747 E005 4451.760393 2.358369e-04 5.023755e-01 6.384443e-01 19 50798194 50798319 126 - 3.520 3.537 0.056
ENSG00000167747 E006 2305.293884 1.742520e-04 5.136648e-01 6.484415e-01 19 50798320 50798334 15 - 3.246 3.249 0.009
ENSG00000167747 E007 2728.479952 1.045159e-04 2.442812e-01 3.792312e-01 19 50798335 50798368 34 - 3.322 3.321 -0.005
ENSG00000167747 E008 1868.338234 5.322351e-05 1.631678e-01 2.792860e-01 19 50798369 50798373 5 - 3.161 3.155 -0.019
ENSG00000167747 E009 4181.320263 1.591702e-04 5.805236e-01 7.052534e-01 19 50798374 50798515 142 - 3.503 3.507 0.016
ENSG00000167747 E010 3625.039198 3.420104e-04 1.653876e-01 2.821983e-01 19 50798516 50798664 149 - 3.424 3.449 0.084
ENSG00000167747 E011 1992.237291 7.697144e-05 6.550801e-06 4.541238e-05 19 50798665 50798703 39 - 3.135 3.193 0.193
ENSG00000167747 E012 3515.530502 4.176506e-04 7.999179e-02 1.595448e-01 19 50798704 50798893 190 - 3.406 3.437 0.103
ENSG00000167747 E013 1649.814241 5.690433e-05 2.002699e-01 3.265556e-01 19 50798894 50798924 31 - 3.106 3.101 -0.018
ENSG00000167747 E014 1645.211420 7.577972e-05 1.043382e-04 5.420099e-04 19 50798925 50798947 23 - 3.129 3.094 -0.116
ENSG00000167747 E015 1565.831762 8.372968e-05 1.251246e-03 4.814069e-03 19 50798948 50798958 11 - 3.102 3.074 -0.095
ENSG00000167747 E016 223.572218 1.272242e-03 2.969119e-16 1.204477e-14 19 50798959 50799031 73 - 2.426 2.178 -0.829
ENSG00000167747 E017 343.448674 9.099695e-04 4.495433e-14 1.342444e-12 19 50799032 50799271 240 - 2.568 2.379 -0.630
ENSG00000167747 E018 270.597502 5.651769e-04 4.235887e-05 2.427406e-04 19 50799272 50799293 22 - 2.403 2.297 -0.354
ENSG00000167747 E019 2151.230583 9.263199e-04 7.261331e-01 8.192366e-01 19 50799294 50799357 64 - 3.204 3.221 0.055
ENSG00000167747 E020 19.144462 9.934362e-04 6.403420e-03 1.967129e-02 19 50801183 50801349 167 - 1.374 1.145 -0.808
ENSG00000167747 E021 20.381834 5.278616e-03 4.466182e-02 9.957816e-02 19 50801989 50802216 228 - 1.362 1.188 -0.611
ENSG00000167747 E022 1649.230582 1.062112e-03 6.906025e-01 7.922572e-01 19 50802217 50802257 41 - 3.088 3.106 0.059
ENSG00000167747 E023 66.352788 4.128591e-04 7.792458e-03 2.325548e-02 19 50802258 50802327 70 - 1.819 1.691 -0.432
ENSG00000167747 E024 61.492137 9.362416e-03 7.409731e-05 3.997697e-04 19 50802328 50802453 126 - 1.887 1.627 -0.881
ENSG00000167747 E025 114.597465 2.793917e-04 4.648603e-05 2.639089e-04 19 50802454 50802614 161 - 2.070 1.920 -0.503
ENSG00000167747 E026 26.672807 7.335600e-04 9.759512e-09 1.205837e-07 19 50802615 50802650 36 - 1.629 1.230 -1.380
ENSG00000167747 E027 79.576589 6.546805e-03 4.530057e-20 2.900323e-18 19 50803553 50803875 323 - 2.153 1.642 -1.719
ENSG00000167747 E028 33.495788 3.575698e-03 1.653336e-07 1.610383e-06 19 50804467 50804571 105 - 1.689 1.331 -1.230
ENSG00000167747 E029 1011.808153 1.246073e-03 8.558985e-02 1.683488e-01 19 50804572 50804929 358 - 2.913 2.885 -0.092