ENSG00000167182

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000376741 ENSG00000167182 HEK293_OSMI2_2hA HEK293_TMG_2hB SP2 protein_coding protein_coding 9.733065 12.78922 9.059669 0.8030827 0.04402512 -0.4969337 8.1978608 11.56593 6.9944244 0.6741255 0.1615236 -0.724790 0.8364917 0.9049667 0.77193333 -0.13303333 5.929813e-06 2.623999e-13 FALSE TRUE
ENST00000637314 ENSG00000167182 HEK293_OSMI2_2hA HEK293_TMG_2hB SP2 protein_coding protein_coding 9.733065 12.78922 9.059669 0.8030827 0.04402512 -0.4969337 0.4200047 0.00000 0.8076795 0.0000000 0.1203853 6.353464 0.0482000 0.0000000 0.08923333 0.08923333 2.623999e-13 2.623999e-13 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000167182 E001 0.0000000       17 47896150 47896181 32 +      
ENSG00000167182 E002 0.9275265 0.0144692287 1.405857e-01 2.488348e-01 17 47896182 47896235 54 + 0.433 0.175 -1.788
ENSG00000167182 E003 1.0726991 0.0117996431 6.452550e-02 1.342572e-01 17 47896236 47896236 1 + 0.497 0.175 -2.109
ENSG00000167182 E004 14.8741106 0.0036883567 4.556822e-04 1.989253e-03 17 47896237 47896261 25 + 1.358 1.048 -1.101
ENSG00000167182 E005 31.0724265 0.0093077545 5.409910e-02 1.164199e-01 17 47896262 47896293 32 + 1.567 1.422 -0.497
ENSG00000167182 E006 0.5169874 0.0199953368 9.231361e-01 9.555324e-01 17 47896294 47896337 44 + 0.155 0.175 0.214
ENSG00000167182 E007 7.6351326 0.0021379795 1.004104e-02 2.886431e-02 17 47897815 47897927 113 + 1.083 0.793 -1.094
ENSG00000167182 E008 0.2944980 0.3412096711 1.464927e-01   17 47908600 47908697 98 + 0.268 0.000 -10.766
ENSG00000167182 E009 2.0940877 0.0087341701 7.222401e-01 8.163953e-01 17 47909664 47909730 67 + 0.496 0.437 -0.298
ENSG00000167182 E010 1.6586859 0.0088193223 1.391838e-01 2.469419e-01 17 47914726 47914861 136 + 0.552 0.299 -1.370
ENSG00000167182 E011 48.7136332 0.0154619934 1.333533e-02 3.670190e-02 17 47915312 47915388 77 + 1.784 1.595 -0.641
ENSG00000167182 E012 315.5450650 0.0006840619 1.595875e-08 1.894322e-07 17 47916156 47917130 975 + 2.538 2.429 -0.366
ENSG00000167182 E013 147.7467826 0.0004640779 5.278358e-01 6.608132e-01 17 47922962 47923274 313 + 2.123 2.145 0.073
ENSG00000167182 E014 106.0172745 0.0038549622 2.647557e-01 4.027437e-01 17 47924919 47925093 175 + 1.956 2.012 0.187
ENSG00000167182 E015 107.1566471 0.0022964374 4.918544e-01 6.291039e-01 17 47925348 47925541 194 + 1.982 2.013 0.105
ENSG00000167182 E016 90.8169216 0.0004107742 1.826846e-01 3.045499e-01 17 47927724 47927820 97 + 1.894 1.948 0.182
ENSG00000167182 E017 140.6923456 0.0005343513 1.078686e-01 2.023786e-01 17 47927821 47928153 333 + 2.085 2.138 0.178
ENSG00000167182 E018 234.5747850 0.0026765384 1.987849e-08 2.319059e-07 17 47928154 47928935 782 + 2.212 2.394 0.609
ENSG00000167182 E019 10.6728296 0.0016090703 8.392106e-03 2.476957e-02 17 47928936 47928965 30 + 0.817 1.119 1.128
ENSG00000167182 E020 4.9328011 0.0032387134 5.352243e-01 6.671490e-01 17 47928966 47929060 95 + 0.685 0.775 0.366
ENSG00000167182 E021 1.6459104 0.4097828744 5.530881e-01 6.823005e-01 17 47929061 47929338 278 + 0.268 0.448 1.083
ENSG00000167182 E022 2.4971527 0.0134312796 1.218387e-01 2.225433e-01 17 47929662 47929733 72 + 0.685 0.436 -1.151
ENSG00000167182 E023 12.7369500 0.0013873401 4.548676e-01 5.954484e-01 17 47929734 47930247 514 + 1.154 1.085 -0.248