ENSG00000167110

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000421699 ENSG00000167110 HEK293_OSMI2_2hA HEK293_TMG_2hB GOLGA2 protein_coding protein_coding 19.75956 21.15319 16.14478 0.4569211 0.273594 -0.3895959 1.4700050 1.019668 0.9944414 0.6761219 0.16305035 -0.03578632 0.07349167 0.04690000 0.06196667 0.01506667 7.448685e-01 1.654894e-08 FALSE TRUE
ENST00000490628 ENSG00000167110 HEK293_OSMI2_2hA HEK293_TMG_2hB GOLGA2 protein_coding protein_coding 19.75956 21.15319 16.14478 0.4569211 0.273594 -0.3895959 2.0311657 3.031327 1.4294610 0.0383844 0.22776529 -1.07917208 0.10136667 0.14350000 0.08820000 -0.05530000 7.981640e-02 1.654894e-08 FALSE FALSE
ENST00000611957 ENSG00000167110 HEK293_OSMI2_2hA HEK293_TMG_2hB GOLGA2 protein_coding protein_coding 19.75956 21.15319 16.14478 0.4569211 0.273594 -0.3895959 0.5881018 1.475942 0.0000000 0.7591413 0.00000000 -7.21523403 0.02825000 0.07133333 0.00000000 -0.07133333 1.727444e-01 1.654894e-08 FALSE TRUE
ENST00000687179 ENSG00000167110 HEK293_OSMI2_2hA HEK293_TMG_2hB GOLGA2 protein_coding protein_coding 19.75956 21.15319 16.14478 0.4569211 0.273594 -0.3895959 1.8302617 1.649915 3.0918218 0.9023830 0.08468015 0.90200631 0.09530417 0.07626667 0.19146667 0.11520000 5.454709e-01 1.654894e-08 FALSE TRUE
ENST00000693185 ENSG00000167110 HEK293_OSMI2_2hA HEK293_TMG_2hB GOLGA2 protein_coding protein_coding 19.75956 21.15319 16.14478 0.4569211 0.273594 -0.3895959 8.7301384 8.976822 6.9790331 0.6853259 0.23372606 -0.36271816 0.44467500 0.42610000 0.43230000 0.00620000 9.904318e-01 1.654894e-08 FALSE TRUE
ENST00000693514 ENSG00000167110 HEK293_OSMI2_2hA HEK293_TMG_2hB GOLGA2 protein_coding retained_intron 19.75956 21.15319 16.14478 0.4569211 0.273594 -0.3895959 1.2323187 3.029205 0.0000000 0.9542473 0.00000000 -8.24755039 0.05752083 0.14340000 0.00000000 -0.14340000 1.654894e-08 1.654894e-08 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000167110 E001 2.0636342 0.1500569951 1.294119e-01 2.333516e-01 9 128255829 128255835 7 - 0.247 0.595 1.937
ENSG00000167110 E002 11.3068066 0.0023871099 1.197076e-01 2.195568e-01 9 128255836 128255889 54 - 0.974 1.137 0.594
ENSG00000167110 E003 31.4164256 0.0006263022 6.093825e-05 3.360864e-04 9 128255890 128255926 37 - 1.304 1.577 0.942
ENSG00000167110 E004 33.7138832 0.0006359598 7.644066e-07 6.513788e-06 9 128255927 128255937 11 - 1.287 1.620 1.146
ENSG00000167110 E005 333.4818573 0.0023135713 6.070152e-10 9.375978e-09 9 128255938 128256638 701 - 2.381 2.571 0.634
ENSG00000167110 E006 52.7207532 0.0006441292 1.595086e-02 4.262120e-02 9 128256639 128256642 4 - 1.631 1.757 0.428
ENSG00000167110 E007 154.6338332 0.0005214414 1.138203e-02 3.207764e-02 9 128256643 128256918 276 - 2.124 2.205 0.271
ENSG00000167110 E008 146.8346883 0.0002918512 6.326336e-01 7.474494e-01 9 128256919 128257087 169 - 2.145 2.162 0.058
ENSG00000167110 E009 149.3743298 0.0002311285 2.040399e-03 7.352307e-03 9 128257088 128257281 194 - 2.098 2.194 0.321
ENSG00000167110 E010 0.3289534 0.0285772990 8.099146e-01   9 128257282 128257305 24 - 0.141 0.106 -0.469
ENSG00000167110 E011 120.0661799 0.0002742739 4.245615e-06 3.069217e-05 9 128257369 128257525 157 - 1.961 2.121 0.537
ENSG00000167110 E012 0.1817044 0.0392711123 6.527696e-01   9 128257526 128257540 15 - 0.000 0.106 10.587
ENSG00000167110 E013 132.7949677 0.0005669357 7.064724e-03 2.139373e-02 9 128257601 128257707 107 - 2.052 2.145 0.309
ENSG00000167110 E014 0.5169874 0.0201784752 7.727866e-01 8.533331e-01 9 128257708 128257789 82 - 0.141 0.191 0.531
ENSG00000167110 E015 129.5616539 0.0002957227 5.817437e-01 7.062364e-01 9 128257790 128257892 103 - 2.089 2.110 0.069
ENSG00000167110 E016 0.4031496 0.0247027400 3.031538e-01 4.450474e-01 9 128257893 128257948 56 - 0.000 0.192 11.590
ENSG00000167110 E017 130.2634003 0.0002900770 3.043599e-01 4.463680e-01 9 128257980 128258198 219 - 2.082 2.118 0.120
ENSG00000167110 E018 54.4844503 0.0004468782 3.426813e-01 4.866963e-01 9 128258455 128258544 90 - 1.699 1.748 0.167
ENSG00000167110 E019 46.6393037 0.0050843037 4.030161e-01 5.468115e-01 9 128258545 128258570 26 - 1.631 1.687 0.192
ENSG00000167110 E020 0.8083901 0.0159160667 9.374373e-01 9.646537e-01 9 128258713 128259006 294 - 0.247 0.262 0.115
ENSG00000167110 E021 73.8185257 0.0006453388 2.758396e-03 9.547793e-03 9 128259007 128259082 76 - 1.772 1.906 0.452
ENSG00000167110 E022 154.6899910 0.0002574817 1.422454e-02 3.873670e-02 9 128259167 128259391 225 - 2.128 2.204 0.253
ENSG00000167110 E023 82.6000105 0.0003169081 9.573187e-01 9.772435e-01 9 128260076 128260125 50 - 1.905 1.905 0.003
ENSG00000167110 E024 89.5590336 0.0003010771 2.216207e-01 3.523391e-01 9 128260126 128260189 64 - 1.966 1.923 -0.146
ENSG00000167110 E025 4.7888670 0.0034499181 1.065412e-01 2.004556e-01 9 128260190 128260464 275 - 0.876 0.662 -0.857
ENSG00000167110 E026 127.4261536 0.0003293470 2.522382e-01 3.885685e-01 9 128260465 128260655 191 - 2.110 2.076 -0.114
ENSG00000167110 E027 97.2142091 0.0004986103 5.179615e-01 6.522704e-01 9 128260656 128260784 129 - 1.957 1.984 0.091
ENSG00000167110 E028 53.6673026 0.0023188292 3.603995e-02 8.366103e-02 9 128260785 128260802 18 - 1.639 1.756 0.400
ENSG00000167110 E029 2.4230582 0.0087449995 8.275299e-03 2.447973e-02 9 128260803 128260867 65 - 0.748 0.323 -2.055
ENSG00000167110 E030 4.5632717 0.0636145956 1.394907e-02 3.810594e-02 9 128260868 128260971 104 - 0.956 0.539 -1.709
ENSG00000167110 E031 3.7007327 0.0058425207 1.952228e-05 1.214088e-04 9 128260972 128261120 149 - 0.956 0.323 -2.864
ENSG00000167110 E032 2.2238489 0.0481730157 1.146251e-02 3.226414e-02 9 128261121 128261171 51 - 0.717 0.263 -2.339
ENSG00000167110 E033 77.3615348 0.0073498340 3.517880e-01 4.960031e-01 9 128261172 128261230 59 - 1.835 1.896 0.203
ENSG00000167110 E034 66.9075006 0.0066033544 5.777019e-01 7.029242e-01 9 128261231 128261259 29 - 1.828 1.801 -0.092
ENSG00000167110 E035 104.2023404 0.0014124475 2.498219e-01 3.857056e-01 9 128261454 128261561 108 - 2.028 1.987 -0.139
ENSG00000167110 E036 67.7594485 0.0004060236 5.409096e-01 6.719587e-01 9 128261668 128261684 17 - 1.833 1.809 -0.081
ENSG00000167110 E037 99.8684565 0.0005294143 4.097396e-01 5.533618e-01 9 128261685 128261757 73 - 2.001 1.973 -0.092
ENSG00000167110 E038 0.4428904 0.4366299129 4.159144e-01 5.592611e-01 9 128261758 128261976 219 - 0.000 0.199 11.660
ENSG00000167110 E039 124.7387390 0.0013376189 8.523778e-02 1.677928e-01 9 128262563 128262704 142 - 2.118 2.059 -0.196
ENSG00000167110 E040 2.2645321 0.0401321032 2.923089e-01 4.332662e-01 9 128262705 128263033 329 - 0.609 0.425 -0.887
ENSG00000167110 E041 91.7032786 0.0007582450 9.457903e-01 9.699721e-01 9 128263034 128263092 59 - 1.952 1.952 0.001
ENSG00000167110 E042 105.9931250 0.0006167225 4.773207e-01 6.158929e-01 9 128265585 128265688 104 - 2.030 2.007 -0.075
ENSG00000167110 E043 54.8721299 0.0024728875 2.323301e-02 5.823144e-02 9 128265689 128265691 3 - 1.802 1.686 -0.392
ENSG00000167110 E044 101.6264381 0.0003263736 1.112215e-01 2.073500e-01 9 128265788 128265869 82 - 2.028 1.974 -0.181
ENSG00000167110 E045 61.4935377 0.0004958673 5.900459e-01 7.129940e-01 9 128265870 128265881 12 - 1.792 1.770 -0.074
ENSG00000167110 E046 2.6185809 0.0056856031 4.133931e-03 1.351722e-02 9 128265882 128265906 25 - 0.777 0.323 -2.170
ENSG00000167110 E047 2.9226690 0.0424765106 1.202817e-02 3.359735e-02 9 128265907 128265949 43 - 0.804 0.376 -1.961
ENSG00000167110 E048 93.5033320 0.0003494531 1.152898e-02 3.241609e-02 9 128265970 128266020 51 - 2.012 1.921 -0.305
ENSG00000167110 E049 8.7174378 0.0046898626 5.392539e-07 4.739505e-06 9 128266021 128266286 266 - 1.233 0.663 -2.159
ENSG00000167110 E050 75.8838770 0.0005629592 9.150614e-06 6.136700e-05 9 128266287 128266316 30 - 1.972 1.792 -0.606
ENSG00000167110 E051 58.7125235 0.0004291337 7.275538e-06 4.988647e-05 9 128266317 128266325 9 - 1.874 1.671 -0.686
ENSG00000167110 E052 6.4120440 0.0026079837 1.492197e-05 9.529488e-05 9 128266326 128267193 868 - 1.110 0.576 -2.101
ENSG00000167110 E053 15.1258408 0.0018114233 9.341901e-01 9.625210e-01 9 128267194 128267259 66 - 1.192 1.202 0.037
ENSG00000167110 E054 10.4152486 0.0180068593 1.728545e-01 2.919149e-01 9 128267260 128267274 15 - 0.938 1.107 0.624
ENSG00000167110 E055 1.1845624 0.0107893461 3.950888e-04 1.755645e-03 9 128267275 128267457 183 - 0.609 0.000 -14.800
ENSG00000167110 E056 101.3330036 0.0002910755 1.018950e-04 5.306571e-04 9 128267458 128267517 60 - 2.073 1.938 -0.450
ENSG00000167110 E057 100.8867412 0.0047768753 2.365812e-04 1.118924e-03 9 128267934 128267997 64 - 2.093 1.922 -0.575
ENSG00000167110 E058 81.1127311 0.0003507365 6.876905e-05 3.741768e-04 9 128268117 128268160 44 - 1.989 1.836 -0.516
ENSG00000167110 E059 109.6936126 0.0007152213 2.773030e-05 1.662476e-04 9 128268420 128268524 105 - 2.114 1.969 -0.486
ENSG00000167110 E060 6.0797520 0.0041977290 3.692300e-03 1.227357e-02 9 128268525 128269459 935 - 1.024 0.662 -1.412
ENSG00000167110 E061 10.6144728 0.0099064261 7.508718e-06 5.131133e-05 9 128270316 128272784 2469 - 1.288 0.797 -1.805
ENSG00000167110 E062 24.6950695 0.0081588854 1.672916e-02 4.434248e-02 9 128272785 128272865 81 - 1.500 1.311 -0.654
ENSG00000167110 E063 14.7661238 0.0011994311 2.392143e-02 5.964128e-02 9 128273640 128273849 210 - 1.040 1.252 0.761
ENSG00000167110 E064 101.4105158 0.0007385562 3.290986e-02 7.762391e-02 9 128273850 128273972 123 - 2.042 1.966 -0.253
ENSG00000167110 E065 50.6021468 0.0004435479 7.141699e-01 8.104660e-01 9 128275893 128276026 134 - 1.682 1.703 0.072