ENSG00000167103

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000388747 ENSG00000167103 HEK293_OSMI2_2hA HEK293_TMG_2hB PIP5KL1 protein_coding protein_coding 1.979637 2.426679 1.806421 0.1932326 0.3432653 -0.4238171 0.8554189 1.1463205 0.62925432 0.122168189 0.060480162 -0.8550794 0.4522417 0.47360000 0.37806667 -0.09553333 0.67790105 0.02427172 FALSE TRUE
ENST00000476624 ENSG00000167103 HEK293_OSMI2_2hA HEK293_TMG_2hB PIP5KL1 protein_coding processed_transcript 1.979637 2.426679 1.806421 0.1932326 0.3432653 -0.4238171 0.2758908 0.5232600 0.09103088 0.159962747 0.003571018 -2.4000429 0.1349875 0.20746667 0.05406667 -0.15340000 0.02427172 0.02427172 FALSE FALSE
ENST00000485562 ENSG00000167103 HEK293_OSMI2_2hA HEK293_TMG_2hB PIP5KL1 protein_coding processed_transcript 1.979637 2.426679 1.806421 0.1932326 0.3432653 -0.4238171 0.2087479 0.1582980 0.26129102 0.158298049 0.027320017 0.6888229 0.1084542 0.06126667 0.15026667 0.08900000 0.33203469 0.02427172   FALSE
ENST00000490773 ENSG00000167103 HEK293_OSMI2_2hA HEK293_TMG_2hB PIP5KL1 protein_coding processed_transcript 1.979637 2.426679 1.806421 0.1932326 0.3432653 -0.4238171 0.1542190 0.1102705 0.31683391 0.002476129 0.115673362 1.4422746 0.0720625 0.04616667 0.16800000 0.12183333 0.03823992 0.02427172   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000167103 E001 4.0825808 0.004206889 0.45682050 0.59718788 9 127920881 127920981 101 - 0.604 0.714 0.466
ENSG00000167103 E002 9.7876920 0.001954122 0.29181655 0.43272835 9 127920982 127921082 101 - 0.921 1.034 0.420
ENSG00000167103 E003 10.5111645 0.002004217 0.80960887 0.87913319 9 127921083 127921221 139 - 1.021 1.044 0.083
ENSG00000167103 E004 8.8077313 0.002146932 0.62241956 0.73922199 9 127921222 127921372 151 - 1.003 0.947 -0.207
ENSG00000167103 E005 10.2432745 0.001896764 0.24224659 0.37683842 9 127921373 127921528 156 - 1.102 0.982 -0.440
ENSG00000167103 E006 9.3503157 0.002122850 0.99381872 1.00000000 9 127921529 127921604 76 - 0.984 0.982 -0.007
ENSG00000167103 E007 12.3306626 0.013536962 0.13146229 0.23617957 9 127921605 127921736 132 - 0.984 1.151 0.609
ENSG00000167103 E008 8.1101829 0.002404171 0.89096492 0.93437106 9 127921737 127921775 39 - 0.921 0.935 0.053
ENSG00000167103 E009 6.8556932 0.002706566 0.76663897 0.84908308 9 127921776 127921789 14 - 0.848 0.882 0.133
ENSG00000167103 E010 18.7764960 0.002070488 0.08638761 0.16962153 9 127921790 127922114 325 - 1.171 1.309 0.489
ENSG00000167103 E011 7.7876907 0.002368979 0.04057722 0.09208210 9 127925107 127925134 28 - 1.055 0.823 -0.875
ENSG00000167103 E012 6.9426803 0.002745732 0.07323217 0.14868941 9 127925135 127925135 1 - 1.003 0.789 -0.814
ENSG00000167103 E013 10.0268770 0.001898770 0.04032800 0.09163370 9 127925136 127925203 68 - 1.144 0.935 -0.767
ENSG00000167103 E014 6.7053394 0.002663216 0.32377844 0.46710521 9 127925204 127925231 28 - 0.943 0.822 -0.461
ENSG00000167103 E015 7.2642563 0.002477778 0.67319974 0.77896272 9 127925232 127925260 29 - 0.921 0.868 -0.201
ENSG00000167103 E016 1.1436731 0.011127644 0.72712497 0.81994940 9 127925261 127925325 65 - 0.361 0.297 -0.400
ENSG00000167103 E017 5.1367562 0.043522483 0.68149137 0.78515694 9 127925496 127925823 328 - 0.726 0.786 0.244
ENSG00000167103 E018 10.5437404 0.001773769 0.05640879 0.12043677 9 127925867 127925957 91 - 0.874 1.081 0.772
ENSG00000167103 E019 6.2301244 0.005616848 0.18381226 0.30600164 9 127925958 127925979 22 - 0.689 0.869 0.719
ENSG00000167103 E020 6.8559814 0.006711305 0.94658635 0.97048384 9 127927153 127927208 56 - 0.848 0.855 0.027
ENSG00000167103 E021 0.8136755 0.014518488 0.28877083 0.42940274 9 127927209 127927296 88 - 0.361 0.173 -1.399
ENSG00000167103 E022 5.7134146 0.166411671 0.68113975 0.78491382 9 127927297 127927331 35 - 0.791 0.781 -0.037
ENSG00000167103 E023 0.4460135 0.025720249 0.02795782 0.06793204 9 127927332 127927491 160 - 0.361 0.000 -11.213
ENSG00000167103 E024 8.6367338 0.002129774 0.72068116 0.81526683 9 127927648 127927772 125 - 0.921 0.959 0.144
ENSG00000167103 E025 1.6273511 0.008834722 0.13354416 0.23906283 9 127927777 127928064 288 - 0.555 0.297 -1.399
ENSG00000167103 E026 8.1971648 0.002431098 0.73228189 0.82377473 9 127928065 127928219 155 - 0.898 0.935 0.141
ENSG00000167103 E027 4.6350677 0.003727213 0.11331873 0.21036024 9 127928433 127928483 51 - 0.555 0.789 0.993
ENSG00000167103 E028 1.7295487 0.026680777 0.01897363 0.04927650 9 127928578 127928655 78 - 0.648 0.240 -2.228
ENSG00000167103 E029 1.7317388 0.008233104 0.01532330 0.04122284 9 127928656 127928791 136 - 0.649 0.240 -2.229
ENSG00000167103 E030 5.0436176 0.003615506 0.54226130 0.67304207 9 127929688 127929885 198 - 0.689 0.772 0.339
ENSG00000167103 E031 1.8329122 0.010373239 0.05751522 0.12235781 9 127930723 127930792 70 - 0.156 0.507 2.358