ENSG00000166352

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000334307 ENSG00000166352 HEK293_OSMI2_2hA HEK293_TMG_2hB IFTAP protein_coding protein_coding 10.29937 7.371841 15.78313 0.6147381 0.5242919 1.097245 2.4219890 2.2384821 3.5388342 0.42963680 0.8114073 0.6583938 0.24095417 0.2985000 0.22670000 -0.07180000 6.510571e-01 2.514477e-06 FALSE  
ENST00000446510 ENSG00000166352 HEK293_OSMI2_2hA HEK293_TMG_2hB IFTAP protein_coding protein_coding 10.29937 7.371841 15.78313 0.6147381 0.5242919 1.097245 0.6817777 0.0000000 1.2180014 0.00000000 0.4520036 6.9401684 0.05665000 0.0000000 0.07660000 0.07660000 1.743368e-05 2.514477e-06 FALSE  
ENST00000527108 ENSG00000166352 HEK293_OSMI2_2hA HEK293_TMG_2hB IFTAP protein_coding protein_coding 10.29937 7.371841 15.78313 0.6147381 0.5242919 1.097245 0.2586169 0.3837910 0.0000000 0.24315080 0.0000000 -5.2993583 0.03448333 0.0505000 0.00000000 -0.05050000 7.172031e-02 2.514477e-06 FALSE  
ENST00000531554 ENSG00000166352 HEK293_OSMI2_2hA HEK293_TMG_2hB IFTAP protein_coding protein_coding 10.29937 7.371841 15.78313 0.6147381 0.5242919 1.097245 4.4633494 2.9598051 6.9052997 0.25748451 0.7661288 1.2194235 0.42452083 0.4013667 0.43523333 0.03386667 7.835685e-01 2.514477e-06 FALSE  
ENST00000534635 ENSG00000166352 HEK293_OSMI2_2hA HEK293_TMG_2hB IFTAP protein_coding protein_coding 10.29937 7.371841 15.78313 0.6147381 0.5242919 1.097245 0.4763060 0.8522980 0.5935983 0.07263653 0.2968318 -0.5145979 0.05452917 0.1179667 0.03790000 -0.08006667 4.023576e-01 2.514477e-06 FALSE  
ENST00000617650 ENSG00000166352 HEK293_OSMI2_2hA HEK293_TMG_2hB IFTAP protein_coding protein_coding 10.29937 7.371841 15.78313 0.6147381 0.5242919 1.097245 0.6874458 0.3382961 1.3660012 0.13961978 0.1622908 1.9820955 0.06480000 0.0469000 0.08686667 0.03996667 4.302452e-01 2.514477e-06 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000166352 E001 0.0000000       11 36594369 36594486 118 +      
ENSG00000166352 E002 0.0000000       11 36594487 36594492 6 +      
ENSG00000166352 E003 0.0000000       11 36594493 36594498 6 +      
ENSG00000166352 E004 0.2934659 0.0285918286 0.6324611090   11 36594499 36594500 2 + 0.091 0.162 0.945
ENSG00000166352 E005 0.2934659 0.0285918286 0.6324611090   11 36594501 36594501 1 + 0.091 0.162 0.945
ENSG00000166352 E006 0.2934659 0.0285918286 0.6324611090   11 36594502 36594507 6 + 0.091 0.162 0.945
ENSG00000166352 E007 0.6621601 0.0164400253 0.5209189643 0.654857485 11 36594508 36594512 5 + 0.167 0.280 0.948
ENSG00000166352 E008 3.1419230 0.0109215583 0.6040782152 0.724717123 11 36594513 36594515 3 + 0.581 0.664 0.360
ENSG00000166352 E009 8.8794079 0.0021158042 0.2953210124 0.436459848 11 36594516 36594523 8 + 0.941 1.056 0.426
ENSG00000166352 E010 18.3828817 0.0021075160 0.0719149107 0.146517369 11 36594524 36594530 7 + 1.330 1.176 -0.542
ENSG00000166352 E011 26.9391770 0.0007420557 0.0712759319 0.145442331 11 36594531 36594538 8 + 1.481 1.356 -0.434
ENSG00000166352 E012 27.3788477 0.0007065169 0.0503442691 0.109774878 11 36594539 36594539 1 + 1.491 1.356 -0.468
ENSG00000166352 E013 39.8602265 0.0005656936 0.0039330159 0.012953948 11 36594540 36594545 6 + 1.658 1.489 -0.578
ENSG00000166352 E014 110.2282886 0.0002720946 0.2910232918 0.431836969 11 36594546 36594592 47 + 2.050 2.015 -0.118
ENSG00000166352 E015 76.5849835 0.0009804200 0.4671257073 0.606636760 11 36594593 36594620 28 + 1.891 1.860 -0.107
ENSG00000166352 E016 77.3196095 0.0009902362 0.8704445926 0.920675540 11 36594621 36594641 21 + 1.879 1.886 0.022
ENSG00000166352 E017 22.4829280 0.0135521219 0.7288398185 0.821214350 11 36594642 36594696 55 + 1.349 1.380 0.106
ENSG00000166352 E018 21.4466129 0.0072019875 0.8321599898 0.894809451 11 36594697 36594761 65 + 1.349 1.329 -0.070
ENSG00000166352 E019 4.5635247 0.1696976540 0.4196340997 0.562888025 11 36594762 36594772 11 + 0.807 0.611 -0.810
ENSG00000166352 E020 11.5113338 0.0015406999 0.0584080713 0.123899694 11 36594773 36594915 143 + 1.157 0.961 -0.716
ENSG00000166352 E021 0.1451727 0.0430710496 1.0000000000   11 36595200 36595250 51 + 0.091 0.000 -9.209
ENSG00000166352 E022 4.0086924 0.0944219979 0.6404356094 0.753678081 11 36597644 36597730 87 + 0.717 0.625 -0.391
ENSG00000166352 E023 114.3562217 0.0002630270 0.0905722819 0.176030920 11 36610081 36610103 23 + 2.073 2.017 -0.189
ENSG00000166352 E024 191.5976557 0.0002522244 0.9397412515 0.966158677 11 36610104 36610239 136 + 2.273 2.275 0.007
ENSG00000166352 E025 65.8752239 0.0003903887 0.3733740328 0.517818979 11 36633284 36633285 2 + 1.831 1.792 -0.131
ENSG00000166352 E026 95.1226210 0.0002897414 0.7826717968 0.860482044 11 36633286 36633318 33 + 1.969 1.980 0.036
ENSG00000166352 E027 141.9069130 0.0002393143 0.2586297644 0.395935466 11 36633319 36633438 120 + 2.133 2.167 0.115
ENSG00000166352 E028 0.0000000       11 36635429 36636050 622 +      
ENSG00000166352 E029 103.1196211 0.0003439105 0.2470222595 0.382433528 11 36636051 36636117 67 + 1.990 2.032 0.140
ENSG00000166352 E030 167.3506592 0.0010321501 0.0010927571 0.004279422 11 36648016 36648155 140 + 2.176 2.275 0.329
ENSG00000166352 E031 1.5478574 0.2119619886 0.4627184389 0.602573741 11 36648156 36651020 2865 + 0.459 0.281 -1.046
ENSG00000166352 E032 136.9834047 0.0003720249 0.0234367787 0.058655262 11 36659019 36659204 186 + 2.102 2.172 0.234
ENSG00000166352 E033 31.0055550 0.0006501585 0.2770884304 0.416605731 11 36659205 36660040 836 + 1.468 1.537 0.238
ENSG00000166352 E034 13.4373065 0.0150498035 0.0002666449 0.001243785 11 36660041 36661909 1869 + 1.275 0.836 -1.607
ENSG00000166352 E035 0.1482932 0.0407298352 0.2555566277   11 36671276 36671401 126 + 0.000 0.162 9.889
ENSG00000166352 E036 0.0000000       11 36671919 36671997 79 +      
ENSG00000166352 E037 0.0000000       11 36671998 36672085 88 +      
ENSG00000166352 E038 2.0553816 0.1347562058 0.5323626650 0.664737213 11 36673187 36675695 2509 + 0.524 0.375 -0.770