ENSG00000165752

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000298630 ENSG00000165752 HEK293_OSMI2_2hA HEK293_TMG_2hB STK32C protein_coding protein_coding 46.69666 79.55969 24.36154 1.161013 0.2012431 -1.707021 7.975588 13.826306 5.149732 0.3439850 0.2471970 -1.423091 0.1712125 0.1737667 0.2112667 0.03750000 0.1040791807 0.0001960816 FALSE  
ENST00000368619 ENSG00000165752 HEK293_OSMI2_2hA HEK293_TMG_2hB STK32C protein_coding protein_coding 46.69666 79.55969 24.36154 1.161013 0.2012431 -1.707021 8.068838 12.396225 5.042353 1.0768452 0.2883528 -1.296037 0.1798583 0.1555000 0.2072000 0.05170000 0.1575856484 0.0001960816 FALSE  
ENST00000456004 ENSG00000165752 HEK293_OSMI2_2hA HEK293_TMG_2hB STK32C protein_coding protein_coding 46.69666 79.55969 24.36154 1.161013 0.2012431 -1.707021 9.991132 14.449193 4.137510 0.9457837 0.4207313 -1.801670 0.2253167 0.1820333 0.1695667 -0.01246667 0.8653362553 0.0001960816 FALSE  
MSTRG.4832.11 ENSG00000165752 HEK293_OSMI2_2hA HEK293_TMG_2hB STK32C protein_coding   46.69666 79.55969 24.36154 1.161013 0.2012431 -1.707021 5.621649 9.569223 1.984565 0.3956745 0.1784222 -2.263835 0.1171208 0.1203333 0.0814000 -0.03893333 0.0513114426 0.0001960816 FALSE  
MSTRG.4832.2 ENSG00000165752 HEK293_OSMI2_2hA HEK293_TMG_2hB STK32C protein_coding   46.69666 79.55969 24.36154 1.161013 0.2012431 -1.707021 7.641551 15.744165 2.851534 0.7454024 0.2078657 -2.460872 0.1448583 0.1977667 0.1171333 -0.08063333 0.0001960816 0.0001960816 FALSE  
MSTRG.4832.8 ENSG00000165752 HEK293_OSMI2_2hA HEK293_TMG_2hB STK32C protein_coding   46.69666 79.55969 24.36154 1.161013 0.2012431 -1.707021 5.563673 10.322129 4.292451 0.2456386 0.3732100 -1.263907 0.1222042 0.1298667 0.1764333 0.04656667 0.1419737757 0.0001960816    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000165752 E001 0.5159433 0.2395919054 1.314605e-01 2.361786e-01 10 132207369 132207421 53 - 0.359 0.067 -2.937
ENSG00000165752 E002 1.2146350 0.1149011813 2.488624e-01 3.845972e-01 10 132207422 132207491 70 - 0.466 0.222 -1.531
ENSG00000165752 E003 182.4696144 0.0002626643 4.568573e-06 3.282148e-05 10 132207492 132207796 305 - 2.008 2.170 0.542
ENSG00000165752 E004 343.7672411 0.0001704459 1.303609e-09 1.891871e-08 10 132207797 132208151 355 - 2.287 2.440 0.510
ENSG00000165752 E005 159.2778154 0.0055198552 6.629952e-02 1.372158e-01 10 132209034 132209101 68 - 2.005 2.098 0.311
ENSG00000165752 E006 5.6637676 0.0029639411 9.042825e-02 1.757982e-01 10 132209295 132209364 70 - 0.466 0.762 1.312
ENSG00000165752 E007 220.6049790 0.0007174378 1.426552e-01 2.516444e-01 10 132222641 132222772 132 - 2.185 2.230 0.151
ENSG00000165752 E008 204.7054616 0.0001878831 4.519175e-02 1.005466e-01 10 132222861 132222986 126 - 2.141 2.203 0.206
ENSG00000165752 E009 202.7420757 0.0010477080 8.128378e-02 1.615587e-01 10 132224407 132224523 117 - 2.139 2.199 0.200
ENSG00000165752 E010 203.6902726 0.0002284366 5.867309e-01 7.102337e-01 10 132225233 132225336 104 - 2.207 2.188 -0.063
ENSG00000165752 E011 200.6520311 0.0002553083 1.240362e-01 2.257247e-01 10 132225527 132225616 90 - 2.224 2.174 -0.165
ENSG00000165752 E012 134.6436507 0.0002330822 1.371569e-01 2.441276e-01 10 132225747 132225784 38 - 2.059 2.002 -0.192
ENSG00000165752 E013 2.6788530 0.0066402295 9.575721e-01 9.774065e-01 10 132226771 132226794 24 - 0.466 0.474 0.041
ENSG00000165752 E014 108.7211293 0.0012038636 2.676052e-01 4.059267e-01 10 132226795 132226819 25 - 1.959 1.908 -0.171
ENSG00000165752 E015 165.5094474 0.0002608248 4.079161e-01 5.515082e-01 10 132226820 132226968 149 - 2.125 2.094 -0.102
ENSG00000165752 E016 187.1743342 0.0002675349 9.536536e-01 9.749752e-01 10 132227977 132228128 152 - 2.159 2.155 -0.014
ENSG00000165752 E017 8.2580479 0.0354515169 1.720800e-01 2.909081e-01 10 132228129 132228189 61 - 1.026 0.820 -0.780
ENSG00000165752 E018 123.9702420 0.0002552171 2.615698e-01 3.992235e-01 10 132245900 132245955 56 - 2.016 1.970 -0.154
ENSG00000165752 E019 23.5871459 0.0010884152 9.535908e-01 9.749321e-01 10 132249030 132249108 79 - 1.278 1.271 -0.026
ENSG00000165752 E020 0.2214452 0.0388112743 1.000000e+00   10 132306922 132307214 293 - 0.001 0.066 6.893
ENSG00000165752 E021 91.5017462 0.0003360456 1.438596e-03 5.435209e-03 10 132307572 132307950 379 - 1.959 1.817 -0.475
ENSG00000165752 E022 56.6679617 0.0323571912 7.765057e-02 1.556899e-01 10 132323992 132324036 45 - 1.794 1.607 -0.634
ENSG00000165752 E023 187.1233981 0.0020375217 1.214534e-04 6.205226e-04 10 132324037 132324373 337 - 2.268 2.128 -0.469
ENSG00000165752 E024 0.8846495 0.0173452103 1.000000e+00 1.000000e+00 10 132330281 132330286 6 - 0.215 0.220 0.040
ENSG00000165752 E025 107.9341692 0.0071228550 1.360156e-01 2.424995e-01 10 132330287 132330485 199 - 1.847 1.937 0.301
ENSG00000165752 E026 138.7952666 0.0025655484 5.341269e-02 1.152255e-01 10 132331436 132331481 46 - 2.097 2.013 -0.281
ENSG00000165752 E027 338.3687641 0.0001453870 2.192684e-03 7.819245e-03 10 132331482 132331869 388 - 2.469 2.397 -0.240