ENSG00000164897

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000297533 ENSG00000164897 HEK293_OSMI2_2hA HEK293_TMG_2hB TMUB1 protein_coding protein_coding 98.48568 170.3963 56.98095 8.055927 1.499865 -1.580174 49.68482 83.83350 26.374836 9.793404 0.2292559 -1.667990 0.4882417 0.4889667 0.4634000 -0.025566667 0.8480834 0.0241607 FALSE  
ENST00000392818 ENSG00000164897 HEK293_OSMI2_2hA HEK293_TMG_2hB TMUB1 protein_coding protein_coding 98.48568 170.3963 56.98095 8.055927 1.499865 -1.580174 11.17188 21.18519 7.007728 1.455445 0.9872414 -1.594661 0.1063500 0.1244000 0.1225667 -0.001833333 0.9794977 0.0241607 FALSE  
ENST00000462940 ENSG00000164897 HEK293_OSMI2_2hA HEK293_TMG_2hB TMUB1 protein_coding protein_coding 98.48568 170.3963 56.98095 8.055927 1.499865 -1.580174 11.13153 17.45766 6.011227 2.164780 1.1168192 -1.536557 0.1110875 0.1017667 0.1059000 0.004133333 1.0000000 0.0241607 FALSE  
MSTRG.30930.8 ENSG00000164897 HEK293_OSMI2_2hA HEK293_TMG_2hB TMUB1 protein_coding   98.48568 170.3963 56.98095 8.055927 1.499865 -1.580174 16.32004 23.81425 11.808136 1.677955 0.6563551 -1.011428 0.1934333 0.1400333 0.2077667 0.067733333 0.0241607 0.0241607 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000164897 E001 2.874187 6.750780e-03 2.696920e-01 4.082259e-01 7 151081085 151081085 1 - 0.346 0.557 1.097
ENSG00000164897 E002 184.290949 4.383516e-03 7.246115e-01 8.180827e-01 7 151081086 151081201 116 - 2.175 2.160 -0.049
ENSG00000164897 E003 649.198299 6.644885e-03 3.606958e-01 5.050461e-01 7 151081202 151081483 282 - 2.732 2.702 -0.101
ENSG00000164897 E004 294.673649 8.577139e-03 1.786391e-01 2.994471e-01 7 151081484 151081495 12 - 2.410 2.352 -0.194
ENSG00000164897 E005 1232.666750 7.321966e-05 3.327768e-04 1.511401e-03 7 151081496 151081777 282 - 2.947 2.990 0.143
ENSG00000164897 E006 720.073123 2.224622e-03 8.740283e-04 3.523397e-03 7 151081778 151081833 56 - 2.677 2.769 0.307
ENSG00000164897 E007 789.593556 1.619801e-03 1.665013e-01 2.836616e-01 7 151081834 151081900 67 - 2.765 2.799 0.115
ENSG00000164897 E008 6.626681 2.782038e-03 5.107404e-01 6.459133e-01 7 151081901 151081916 16 - 0.721 0.817 0.384
ENSG00000164897 E009 1716.593040 9.417121e-04 4.818684e-01 6.200781e-01 7 151082175 151082458 284 - 3.119 3.132 0.045
ENSG00000164897 E010 979.558512 1.045649e-04 1.441206e-01 2.536154e-01 7 151082459 151082593 135 - 2.866 2.886 0.065
ENSG00000164897 E011 117.718444 6.827228e-03 7.241725e-01 8.177746e-01 7 151082594 151082667 74 - 1.951 1.972 0.069
ENSG00000164897 E012 115.673308 1.340940e-02 2.710652e-01 4.097614e-01 7 151082668 151082741 74 - 2.019 1.945 -0.249
ENSG00000164897 E013 128.734717 2.267096e-03 1.077864e-03 4.227529e-03 7 151082742 151082763 22 - 2.112 1.975 -0.460
ENSG00000164897 E014 428.060971 2.169252e-04 5.101291e-05 2.868835e-04 7 151082764 151082917 154 - 2.592 2.507 -0.283
ENSG00000164897 E015 268.236631 1.350844e-03 6.572805e-07 5.678317e-06 7 151082918 151083082 165 - 2.439 2.291 -0.494
ENSG00000164897 E016 30.804930 6.505665e-04 7.201138e-06 4.944131e-05 7 151083083 151083124 42 - 1.627 1.322 -1.049
ENSG00000164897 E017 20.290828 1.878675e-02 1.918489e-05 1.195172e-04 7 151083175 151083337 163 - 1.538 1.108 -1.504
ENSG00000164897 E018 9.964878 6.322805e-03 2.088161e-01 3.370905e-01 7 151083338 151083433 96 - 1.055 0.902 -0.568
ENSG00000164897 E019 302.175130 4.783918e-03 8.354453e-01 8.970895e-01 7 151083434 151083511 78 - 2.363 2.377 0.047