ENSG00000164845

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
MSTRG.6760.1 ENSG00000164845 HEK293_OSMI2_2hA HEK293_TMG_2hB   transcribed_unprocessed_pseudogene   13.7574 23.52118 9.57774 2.214809 0.5323065 -1.295311 3.1043979 3.832821 2.3779678 0.4247583 0.4118306 -0.6863823 0.25722917 0.16786667 0.24976667 0.08190000 0.45872693 0.03324576 FALSE FALSE
MSTRG.6760.14 ENSG00000164845 HEK293_OSMI2_2hA HEK293_TMG_2hB   transcribed_unprocessed_pseudogene   13.7574 23.52118 9.57774 2.214809 0.5323065 -1.295311 1.1606687 1.384960 1.5407593 0.1352672 0.4558541 0.1527515 0.08173333 0.06026667 0.16470000 0.10443333 0.10652771 0.03324576 FALSE TRUE
MSTRG.6760.15 ENSG00000164845 HEK293_OSMI2_2hA HEK293_TMG_2hB   transcribed_unprocessed_pseudogene   13.7574 23.52118 9.57774 2.214809 0.5323065 -1.295311 4.0514189 10.090126 0.7795417 2.6871357 0.7795417 -3.6772139 0.22808750 0.41536667 0.07326667 -0.34210000 0.07240731 0.03324576 FALSE FALSE
MSTRG.6760.2 ENSG00000164845 HEK293_OSMI2_2hA HEK293_TMG_2hB   transcribed_unprocessed_pseudogene   13.7574 23.52118 9.57774 2.214809 0.5323065 -1.295311 1.9602573 3.140658 2.4823614 0.1907402 0.2824236 -0.3381398 0.16841250 0.13690000 0.26053333 0.12363333 0.03324576 0.03324576 FALSE TRUE
MSTRG.6760.3 ENSG00000164845 HEK293_OSMI2_2hA HEK293_TMG_2hB   transcribed_unprocessed_pseudogene   13.7574 23.52118 9.57774 2.214809 0.5323065 -1.295311 0.9401858 1.815614 0.5241777 0.1692388 0.5241777 -1.7729904 0.05985417 0.07733333 0.05836667 -0.01896667 0.30183693 0.03324576 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000164845 E001 21.0203966 0.0009393846 0.120842683 0.22115269 12 8232244 8232332 89 - 1.383 1.275 -0.376
ENSG00000164845 E002 20.2818727 0.0009994134 0.566574628 0.69353198 12 8232333 8232344 12 - 1.320 1.285 -0.122
ENSG00000164845 E003 20.7956525 0.0012244784 0.485437519 0.62330766 12 8232345 8232358 14 - 1.339 1.295 -0.153
ENSG00000164845 E004 20.6034527 0.0049584616 0.452983145 0.59378990 12 8232359 8232364 6 - 1.339 1.289 -0.175
ENSG00000164845 E005 27.2866021 0.0101051667 0.712742388 0.80937797 12 8232365 8232376 12 - 1.430 1.416 -0.047
ENSG00000164845 E006 27.7274162 0.0086377323 0.796120571 0.86983106 12 8232377 8232385 9 - 1.430 1.425 -0.018
ENSG00000164845 E007 29.4372066 0.0116877780 0.821783782 0.88760621 12 8232386 8232409 24 - 1.452 1.452 -0.001
ENSG00000164845 E008 53.5352970 0.0119254332 0.934674642 0.96285688 12 8232410 8232511 102 - 1.683 1.708 0.086
ENSG00000164845 E009 55.5792553 0.0026856305 0.239820154 0.37392356 12 8232512 8232605 94 - 1.662 1.738 0.260
ENSG00000164845 E010 27.5524011 0.0120983964 0.909526492 0.94654449 12 8232606 8232607 2 - 1.399 1.424 0.085
ENSG00000164845 E011 18.0129459 0.0010457452 0.661111043 0.76964275 12 8234134 8234275 142 - 1.211 1.259 0.167
ENSG00000164845 E012 26.5681152 0.0007973489 0.204623278 0.33193987 12 8234276 8234341 66 - 1.459 1.382 -0.266
ENSG00000164845 E013 35.0074688 0.0008633712 0.024489280 0.06083173 12 8234342 8234425 84 - 1.601 1.475 -0.431
ENSG00000164845 E014 4.4971733 0.0736452224 0.398724277 0.54246465 12 8234426 8234426 1 - 0.817 0.664 -0.621
ENSG00000164845 E015 4.6444223 0.1006782748 0.369837945 0.51424957 12 8234427 8234447 21 - 0.846 0.663 -0.742
ENSG00000164845 E016 4.6594857 0.0036765328 0.132910147 0.23815965 12 8235253 8235257 5 - 0.846 0.647 -0.810
ENSG00000164845 E017 13.2744892 0.0249095330 0.345424626 0.48952360 12 8235258 8235516 259 - 1.187 1.079 -0.386
ENSG00000164845 E018 3.4697265 0.0045861650 0.805977178 0.87666990 12 8235517 8235518 2 - 0.577 0.624 0.207
ENSG00000164845 E019 49.8107639 0.0006510544 0.177692692 0.29822748 12 8235601 8235734 134 - 1.704 1.644 -0.203
ENSG00000164845 E020 1.9414671 0.1171643375 0.554141342 0.68315046 12 8236901 8236970 70 - 0.520 0.414 -0.538
ENSG00000164845 E021 2.0156502 0.0083940073 0.956214743 0.97658119 12 8236971 8236972 2 - 0.455 0.452 -0.016
ENSG00000164845 E022 6.1005279 0.0115653865 0.007088692 0.02145943 12 8236973 8237072 100 - 1.030 0.689 -1.321
ENSG00000164845 E023 1.6543178 0.0084284866 0.624679760 0.74094408 12 8238361 8238388 28 - 0.455 0.375 -0.432
ENSG00000164845 E024 32.1179857 0.0036992963 0.301306479 0.44309512 12 8238667 8238671 5 - 1.524 1.461 -0.215
ENSG00000164845 E025 60.4343596 0.0028054603 0.486255453 0.62405266 12 8238672 8238749 78 - 1.715 1.760 0.151
ENSG00000164845 E026 0.7393776 0.4147950170 0.717386921 0.81277652 12 8240642 8240645 4 - 0.284 0.218 -0.504
ENSG00000164845 E027 1.0360657 0.0187878847 0.186503726 0.30935504 12 8240646 8240702 57 - 0.455 0.226 -1.436
ENSG00000164845 E028 0.4439371 0.0215764965 0.019097472 0.04955155 12 8240703 8240706 4 - 0.378 0.000 -10.950
ENSG00000164845 E029 87.9980369 0.0069695581 0.139463774 0.24729265 12 8242752 8242849 98 - 1.842 1.928 0.289
ENSG00000164845 E030 56.0559958 0.0118167076 0.058142643 0.12344308 12 8242850 8242856 7 - 1.606 1.747 0.479
ENSG00000164845 E031 72.8085323 0.0101934305 0.015770885 0.04221711 12 8242857 8242998 142 - 1.704 1.864 0.541
ENSG00000164845 E032 1.1812489 0.0108647759 0.274022960 0.41312134 12 8243811 8244165 355 - 0.165 0.375 1.567