ENSG00000164713

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000297290 ENSG00000164713 HEK293_OSMI2_2hA HEK293_TMG_2hB BRI3 protein_coding protein_coding 124.3185 219.5717 79.71203 4.983281 1.035357 -1.461708 29.57246 38.84384 25.72088 1.253556 1.534088 -0.5945567 0.2499458 0.1768333 0.3229667 0.1461333 1.716639e-07 1.38604e-18 FALSE FALSE
MSTRG.30284.11 ENSG00000164713 HEK293_OSMI2_2hA HEK293_TMG_2hB BRI3 protein_coding   124.3185 219.5717 79.71203 4.983281 1.035357 -1.461708 84.32579 169.83837 44.49625 3.449792 1.606079 -1.9321675 0.6523667 0.7736333 0.5580333 -0.2156000 1.386040e-18 1.38604e-18   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000164713 E001 6.9977545 2.523920e-03 7.164285e-01 8.120840e-01 7 98252355 98252378 24 + 0.804 0.840 0.143
ENSG00000164713 E002 24.0349043 1.427221e-02 5.602547e-01 6.882596e-01 7 98252379 98252528 150 + 1.381 1.313 -0.238
ENSG00000164713 E003 5.0112506 3.304441e-03 9.973166e-01 1.000000e+00 7 98252884 98253017 134 + 0.724 0.712 -0.050
ENSG00000164713 E004 0.0000000       7 98270577 98270635 59 +      
ENSG00000164713 E005 0.0000000       7 98271014 98271041 28 +      
ENSG00000164713 E006 1.6974102 4.846250e-02 5.415184e-04 2.315466e-03 7 98281656 98281666 11 + 0.766 0.145 -3.611
ENSG00000164713 E007 8.6747284 2.035025e-03 1.090693e-12 2.656918e-11 7 98281667 98281685 19 + 1.362 0.576 -2.992
ENSG00000164713 E008 55.6870399 3.789485e-02 7.671476e-12 1.627843e-10 7 98281686 98281821 136 + 2.106 1.377 -2.471
ENSG00000164713 E009 45.7262162 2.439625e-02 1.294877e-08 1.563484e-07 7 98281822 98281835 14 + 1.933 1.407 -1.790
ENSG00000164713 E010 212.4849166 7.021207e-04 8.411340e-04 3.405867e-03 7 98281836 98281937 102 + 2.336 2.226 -0.366
ENSG00000164713 E011 1.3953073 9.888443e-03 8.708074e-01 9.209771e-01 7 98281938 98281977 40 + 0.317 0.339 0.143
ENSG00000164713 E012 0.1482932 4.146729e-02 1.000000e+00   7 98282201 98282232 32 + 0.001 0.078 6.711
ENSG00000164713 E013 376.7727640 8.128684e-04 5.388230e-01 6.702060e-01 7 98282351 98282382 32 + 2.504 2.505 0.003
ENSG00000164713 E014 763.3068523 3.796559e-04 2.141418e-05 1.318230e-04 7 98282383 98282453 71 + 2.771 2.822 0.171
ENSG00000164713 E015 6.9633308 2.744256e-03 2.163651e-02 5.492245e-02 7 98282454 98282706 253 + 1.049 0.758 -1.107
ENSG00000164713 E016 8.7705835 2.739968e-02 2.778576e-02 6.759025e-02 7 98282832 98283010 179 + 1.125 0.820 -1.139
ENSG00000164713 E017 1722.6713586 9.463283e-05 2.562424e-26 3.131894e-24 7 98291111 98291484 374 + 3.110 3.178 0.225
ENSG00000164713 E018 118.7981293 8.036806e-03 2.566314e-03 8.962016e-03 7 98291485 98291545 61 + 1.878 2.042 0.550
ENSG00000164713 E019 11.1754511 1.603279e-03 6.757132e-01 7.808981e-01 7 98292502 98292638 137 + 1.069 1.012 -0.211
ENSG00000164713 E020 19.7596793 9.449898e-04 5.418039e-01 6.727241e-01 7 98292639 98293010 372 + 1.219 1.259 0.142
ENSG00000164713 E021 6.9750343 2.518389e-03 8.491238e-04 3.434549e-03 7 98306483 98306521 39 + 1.107 0.695 -1.579
ENSG00000164713 E022 9.9109272 1.733880e-03 1.555180e-06 1.238593e-05 7 98306522 98306665 144 + 1.296 0.788 -1.871
ENSG00000164713 E023 7.8407639 2.336256e-03 8.897491e-10 1.331650e-08 7 98307137 98307449 313 + 1.296 0.598 -2.665
ENSG00000164713 E024 113.3804342 1.893402e-03 1.466695e-36 4.015332e-34 7 98307515 98310441 2927 + 2.306 1.806 -1.676