ENSG00000164654

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-10 / 10
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000340080	ENSG00000164654	HEK293_OSMI2_2hA	HEK293_TMG_2hB	MIOS	protein_coding	protein_coding	9.349286	3.744749	14.33557	0.2580301	0.3818223	1.933817	0.86775744	0.51112979	1.57475216	0.29552539	0.44477712	1.604543	0.13702083	0.12720000	0.109500000	-0.017700000	0.96954342	0.01579976	FALSE	TRUE
ENST00000405785	ENSG00000164654	HEK293_OSMI2_2hA	HEK293_TMG_2hB	MIOS	protein_coding	protein_coding	9.349286	3.744749	14.33557	0.2580301	0.3818223	1.933817	1.63105071	1.04426749	3.33707808	0.26508011	0.50244298	1.666661	0.19283750	0.29156667	0.233166667	-0.058400000	0.87397823	0.01579976	FALSE	TRUE
ENST00000433056	ENSG00000164654	HEK293_OSMI2_2hA	HEK293_TMG_2hB	MIOS	protein_coding	protein_coding	9.349286	3.744749	14.33557	0.2580301	0.3818223	1.933817	0.06670616	0.30886581	0.00000000	0.30886581	0.00000000	-4.994878	0.01630417	0.07823333	0.000000000	-0.078233333	0.58615944	0.01579976	FALSE	FALSE
ENST00000433635	ENSG00000164654	HEK293_OSMI2_2hA	HEK293_TMG_2hB	MIOS	protein_coding	protein_coding	9.349286	3.744749	14.33557	0.2580301	0.3818223	1.933817	0.91172822	0.10539181	1.80746733	0.10539181	0.60833087	3.977317	0.08272917	0.02600000	0.124200000	0.098200000	0.17686131	0.01579976	FALSE	FALSE
ENST00000445169	ENSG00000164654	HEK293_OSMI2_2hA	HEK293_TMG_2hB	MIOS	protein_coding	protein_coding	9.349286	3.744749	14.33557	0.2580301	0.3818223	1.933817	1.56822194	0.72950881	2.31476816	0.05650916	0.08555875	1.652448	0.16064583	0.19486667	0.161933333	-0.032933333	0.60547254	0.01579976	FALSE	FALSE
ENST00000456533	ENSG00000164654	HEK293_OSMI2_2hA	HEK293_TMG_2hB	MIOS	protein_coding	protein_coding	9.349286	3.744749	14.33557	0.2580301	0.3818223	1.933817	0.97710652	0.06462884	1.90733022	0.06462884	0.09034269	4.683222	0.07841667	0.01636667	0.133100000	0.116733333	0.01579976	0.01579976	FALSE	TRUE
ENST00000493227	ENSG00000164654	HEK293_OSMI2_2hA	HEK293_TMG_2hB	MIOS	protein_coding	retained_intron	9.349286	3.744749	14.33557	0.2580301	0.3818223	1.933817	0.13335371	0.35191917	0.05380607	0.20900534	0.03167588	-2.503902	0.03237500	0.09376667	0.003866667	-0.089900000	0.18814977	0.01579976	FALSE	TRUE
MSTRG.29491.5	ENSG00000164654	HEK293_OSMI2_2hA	HEK293_TMG_2hB	MIOS	protein_coding		9.349286	3.744749	14.33557	0.2580301	0.3818223	1.933817	0.66294543	0.31185621	1.17742066	0.17463729	0.23509924	1.883343	0.08485417	0.08956667	0.081733333	-0.007833333	0.91312686	0.01579976	FALSE	TRUE
MSTRG.29491.7	ENSG00000164654	HEK293_OSMI2_2hA	HEK293_TMG_2hB	MIOS	protein_coding		9.349286	3.744749	14.33557	0.2580301	0.3818223	1.933817	1.50331752	0.00000000	1.13571903	0.00000000	1.13571903	6.840109	0.10274167	0.00000000	0.080766667	0.080766667	1.00000000	0.01579976	FALSE	TRUE
MSTRG.29491.8	ENSG00000164654	HEK293_OSMI2_2hA	HEK293_TMG_2hB	MIOS	protein_coding		9.349286	3.744749	14.33557	0.2580301	0.3818223	1.933817	0.74199938	0.25812820	0.78026852	0.14046738	0.20842159	1.559420	0.07200417	0.06473333	0.054500000	-0.010233333	1.00000000	0.01579976	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 28
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groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000164654	E001	0.4439371	0.0215581171	4.107160e-01	5.543142e-01	7	7566875	7566883	9	+	0.197	0.001	-8.876
ENSG00000164654	E002	7.7094026	0.0023572352	1.256192e-02	3.487782e-02	7	7566884	7566960	77	+	0.983	0.635	-1.376
ENSG00000164654	E003	11.0086673	0.0351702703	5.315712e-02	1.147696e-01	7	7566961	7566987	27	+	1.109	0.817	-1.092
ENSG00000164654	E004	16.3928626	0.0179059901	1.467058e-01	2.572066e-01	7	7566988	7567052	65	+	1.246	1.081	-0.589
ENSG00000164654	E005	15.2289507	0.0411448683	6.287318e-01	7.442181e-01	7	7567053	7567072	20	+	1.196	1.132	-0.227
ENSG00000164654	E006	6.8406583	0.0031235834	3.993608e-03	1.312545e-02	7	7567073	7567155	83	+	0.947	0.507	-1.827
ENSG00000164654	E007	6.1064895	0.0029550222	1.184030e-02	3.315119e-02	7	7567156	7567196	41	+	0.897	0.507	-1.639
ENSG00000164654	E008	10.1431651	0.0146483192	7.069039e-01	8.049771e-01	7	7567197	7567296	100	+	1.016	0.971	-0.169
ENSG00000164654	E009	17.5009896	0.0390079203	2.461267e-01	3.813961e-01	7	7567297	7567482	186	+	1.181	1.323	0.502
ENSG00000164654	E010	8.5748400	0.0270213478	5.892430e-02	1.247913e-01	7	7567483	7567484	2	+	0.853	1.103	0.930
ENSG00000164654	E011	8.3046596	0.0021138047	5.060059e-01	6.417063e-01	7	7567485	7567606	122	+	0.908	0.993	0.321
ENSG00000164654	E012	20.0308263	0.0010629817	1.510670e-02	4.072862e-02	7	7567607	7567688	82	+	1.223	1.422	0.696
ENSG00000164654	E013	37.1217467	0.0104752751	2.305867e-02	5.787258e-02	7	7568026	7568123	98	+	1.487	1.663	0.603
ENSG00000164654	E014	131.5409950	0.0159362790	3.941620e-02	8.995099e-02	7	7572436	7572925	490	+	2.119	1.984	-0.454
ENSG00000164654	E015	182.7267839	0.0028151098	5.667168e-09	7.324519e-08	7	7572926	7573769	844	+	2.277	2.061	-0.722
ENSG00000164654	E016	59.1464999	0.0004432007	3.875463e-03	1.279352e-02	7	7574098	7574196	99	+	1.778	1.634	-0.488
ENSG00000164654	E017	1.1437748	0.0117123649	8.788035e-01	9.261558e-01	7	7581729	7581844	116	+	0.292	0.324	0.210
ENSG00000164654	E018	1.4865465	0.0311781455	8.072338e-01	8.775563e-01	7	7582630	7582819	190	+	0.369	0.325	-0.271
ENSG00000164654	E019	1.4018549	0.2095185307	4.047551e-01	5.484561e-01	7	7582954	7583117	164	+	0.403	0.193	-1.447
ENSG00000164654	E020	97.5250810	0.0002837495	6.238304e-03	1.923830e-02	7	7583118	7583372	255	+	1.983	1.882	-0.339
ENSG00000164654	E021	88.4111890	0.0004295801	9.538341e-02	1.834676e-01	7	7585636	7585805	170	+	1.931	1.869	-0.207
ENSG00000164654	E022	60.1501983	0.0003777984	8.984716e-01	9.392551e-01	7	7588498	7588563	66	+	1.745	1.759	0.048
ENSG00000164654	E023	93.3454913	0.0004513574	3.087392e-01	4.510182e-01	7	7589405	7589563	159	+	1.920	1.968	0.161
ENSG00000164654	E024	81.7780313	0.0026377472	1.234899e-03	4.759199e-03	7	7594980	7595132	153	+	1.827	1.983	0.525
ENSG00000164654	E025	97.6990223	0.0110297777	5.183275e-03	1.642753e-02	7	7596257	7596461	205	+	1.894	2.076	0.611
ENSG00000164654	E026	1.0339748	0.0789505357	5.289968e-02	1.143078e-01	7	7605118	7605941	824	+	0.141	0.507	2.534
ENSG00000164654	E027	88.3107007	0.0382732625	2.083904e-01	3.365437e-01	7	7605942	7606071	130	+	1.860	2.018	0.529
ENSG00000164654	E028	107.9483412	0.0015587937	1.206716e-07	1.207015e-06	7	7606996	7608932	1937	+	1.929	2.139	0.705

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000164654

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3