ENSG00000164638

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000297195 ENSG00000164638 HEK293_OSMI2_2hA HEK293_TMG_2hB SLC29A4 protein_coding protein_coding 4.574732 6.494324 4.133551 0.6813868 0.5321663 -0.6505315 0.5638210 1.7779277 0.0000000 0.9247289 0.00000000 -7.4821446 0.1286250 0.30386667 0.0000000 -0.30386667 0.2158031 0.0192451 FALSE TRUE
ENST00000396872 ENSG00000164638 HEK293_OSMI2_2hA HEK293_TMG_2hB SLC29A4 protein_coding protein_coding 4.574732 6.494324 4.133551 0.6813868 0.5321663 -0.6505315 1.8506563 2.3643814 1.3423258 1.0163739 0.02466368 -0.8121089 0.3897542 0.34390000 0.3335667 -0.01033333 0.9910377 0.0192451 FALSE TRUE
ENST00000406453 ENSG00000164638 HEK293_OSMI2_2hA HEK293_TMG_2hB SLC29A4 protein_coding protein_coding 4.574732 6.494324 4.133551 0.6813868 0.5321663 -0.6505315 0.4075299 0.7948616 0.1019258 0.1516862 0.03066269 -2.8461980 0.0869625 0.12876667 0.0247000 -0.10406667 0.0192451 0.0192451 FALSE TRUE
ENST00000434816 ENSG00000164638 HEK293_OSMI2_2hA HEK293_TMG_2hB SLC29A4 protein_coding protein_coding 4.574732 6.494324 4.133551 0.6813868 0.5321663 -0.6505315 0.6914029 0.4229553 1.4886222 0.4229553 0.80875027 1.7913466 0.1660500 0.05823333 0.3464000 0.28816667 0.4238160 0.0192451 FALSE FALSE
ENST00000444741 ENSG00000164638 HEK293_OSMI2_2hA HEK293_TMG_2hB SLC29A4 protein_coding protein_coding 4.574732 6.494324 4.133551 0.6813868 0.5321663 -0.6505315 0.8495789 0.6368944 1.0791815 0.6368944 0.71771816 0.7516423 0.1869792 0.08990000 0.2614667 0.17156667 0.5581651 0.0192451 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000164638 E001 0.000000       7 5274369 5274491 123 +      
ENSG00000164638 E002 1.880020 0.0151932467 1.548687e-05 9.853374e-05 7 5282943 5282961 19 + 0.839 0.133 -4.039
ENSG00000164638 E003 2.031535 0.0092136631 3.388621e-06 2.507673e-05 7 5282962 5282968 7 + 0.875 0.133 -4.178
ENSG00000164638 E004 4.191340 0.2695133643 5.739515e-03 1.792683e-02 7 5282969 5283011 43 + 1.043 0.424 -2.604
ENSG00000164638 E005 4.335367 0.1713935598 3.821070e-03 1.263907e-02 7 5283012 5283028 17 + 1.043 0.449 -2.468
ENSG00000164638 E006 9.249744 0.0154027819 9.981504e-03 2.871844e-02 7 5283029 5283082 54 + 1.146 0.841 -1.132
ENSG00000164638 E007 3.176275 0.0052568224 1.742628e-01 2.937303e-01 7 5287806 5287808 3 + 0.710 0.499 -0.942
ENSG00000164638 E008 37.960229 0.0009137358 9.876301e-06 6.573110e-05 7 5287809 5287985 177 + 1.689 1.429 -0.889
ENSG00000164638 E009 66.986010 0.0004275236 4.325843e-08 4.725898e-07 7 5290732 5290863 132 + 1.916 1.675 -0.816
ENSG00000164638 E010 74.809427 0.0004107747 8.414719e-03 2.482393e-02 7 5291124 5291237 114 + 1.867 1.757 -0.371
ENSG00000164638 E011 38.845730 0.0055268227 2.336856e-01 3.667644e-01 7 5291693 5291729 37 + 1.561 1.485 -0.260
ENSG00000164638 E012 60.609612 0.0007850828 7.417242e-01 8.307712e-01 7 5291730 5291821 92 + 1.694 1.687 -0.025
ENSG00000164638 E013 24.873146 0.0010852332 8.822891e-01 9.286364e-01 7 5294860 5294864 5 + 1.311 1.309 -0.007
ENSG00000164638 E014 44.852667 0.0075244443 9.280337e-01 9.586848e-01 7 5294865 5294934 70 + 1.554 1.561 0.023
ENSG00000164638 E015 73.688691 0.0045293886 7.399255e-01 8.295015e-01 7 5296936 5297198 263 + 1.747 1.779 0.107
ENSG00000164638 E016 62.690468 0.0007085414 4.886992e-01 6.262309e-01 7 5298988 5299126 139 + 1.662 1.710 0.164
ENSG00000164638 E017 56.527125 0.0017229526 2.808168e-01 4.206922e-01 7 5299240 5299328 89 + 1.595 1.671 0.258
ENSG00000164638 E018 63.017187 0.0005880796 1.079208e-01 2.024488e-01 7 5299329 5299427 99 + 1.621 1.721 0.339
ENSG00000164638 E019 88.265530 0.0025041969 7.974089e-02 1.591516e-01 7 5300422 5300662 241 + 1.765 1.868 0.347
ENSG00000164638 E020 107.477501 0.0003182178 4.494143e-02 1.000919e-01 7 5302797 5303215 419 + 1.857 1.951 0.317
ENSG00000164638 E021 120.529934 0.0015364807 3.202563e-02 7.590970e-02 7 5303216 5303472 257 + 1.904 2.006 0.345
ENSG00000164638 E022 219.226284 0.0085223675 2.211928e-03 7.880008e-03 7 5303473 5306912 3440 + 2.113 2.275 0.543