ENSG00000164338

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000296792 ENSG00000164338 HEK293_OSMI2_2hA HEK293_TMG_2hB UTP15 protein_coding protein_coding 11.16487 3.698994 18.82507 0.4798608 1.109249 2.344321 7.8565910 3.45516344 12.795524 0.31844680 0.5527962 1.885771 0.76028333 0.94243333 0.68126667 -0.2611667 1.100069e-03 2.450668e-06 FALSE TRUE
ENST00000508686 ENSG00000164338 HEK293_OSMI2_2hA HEK293_TMG_2hB UTP15 protein_coding protein_coding 11.16487 3.698994 18.82507 0.4798608 1.109249 2.344321 0.7704926 0.07272256 1.625665 0.03847274 0.1655514 4.305453 0.05520417 0.01820000 0.08590000 0.0677000 1.939743e-03 2.450668e-06   FALSE
ENST00000510478 ENSG00000164338 HEK293_OSMI2_2hA HEK293_TMG_2hB UTP15 protein_coding retained_intron 11.16487 3.698994 18.82507 0.4798608 1.109249 2.344321 1.1760565 0.02704990 2.122442 0.02704990 0.1760440 5.846893 0.07910000 0.00580000 0.11430000 0.1085000 2.450668e-06 2.450668e-06   FALSE
ENST00000512550 ENSG00000164338 HEK293_OSMI2_2hA HEK293_TMG_2hB UTP15 protein_coding retained_intron 11.16487 3.698994 18.82507 0.4798608 1.109249 2.344321 1.1358454 0.11855366 1.899035 0.11855366 0.4491587 3.892401 0.08707083 0.02546667 0.09866667 0.0732000 2.224582e-01 2.450668e-06 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000164338 E001 0.4439371 0.0215849974 5.501427e-01 6.798002e-01 5 73565443 73565740 298 + 0.174 0.000 -8.806
ENSG00000164338 E002 0.4439371 0.0215849974 5.501427e-01 6.798002e-01 5 73565741 73565742 2 + 0.174 0.000 -8.803
ENSG00000164338 E003 0.6653823 0.0172671820 8.792264e-01 9.264213e-01 5 73565743 73565753 11 + 0.174 0.216 0.386
ENSG00000164338 E004 7.5162950 0.0052803629 5.751091e-01 7.008272e-01 5 73565754 73565772 19 + 0.879 0.832 -0.182
ENSG00000164338 E005 61.0849869 0.0005132427 5.595918e-04 2.383386e-03 5 73565773 73565912 140 + 1.758 1.598 -0.542
ENSG00000164338 E006 8.4734257 0.0019401100 5.382490e-04 2.303098e-03 5 73565913 73566186 274 + 0.995 0.467 -2.201
ENSG00000164338 E007 128.1763592 0.0002478185 5.780018e-03 1.803371e-02 5 73567262 73567434 173 + 2.058 1.992 -0.221
ENSG00000164338 E008 6.9471107 0.0024198269 7.014396e-04 2.904350e-03 5 73567435 73567677 243 + 0.924 0.359 -2.523
ENSG00000164338 E009 93.3080035 0.0004746149 2.814395e-02 6.829670e-02 5 73568235 73568291 57 + 1.920 1.860 -0.202
ENSG00000164338 E010 79.4221209 0.0005563534 3.191898e-02 7.569981e-02 5 73568292 73568327 36 + 1.852 1.785 -0.226
ENSG00000164338 E011 136.6044372 0.0033562161 3.845176e-01 5.286643e-01 5 73568420 73568604 185 + 2.070 2.063 -0.021
ENSG00000164338 E012 143.0926568 0.0049439404 3.834247e-01 5.276288e-01 5 73569497 73569675 179 + 2.090 2.078 -0.039
ENSG00000164338 E013 126.5375116 0.0003015496 2.903097e-01 4.311031e-01 5 73570586 73570711 126 + 2.036 2.033 -0.008
ENSG00000164338 E014 132.7383889 0.0002465635 4.010368e-02 9.122596e-02 5 73572489 73572624 136 + 2.065 2.028 -0.126
ENSG00000164338 E015 116.8554991 0.0002722951 1.055035e-02 3.009143e-02 5 73576952 73577036 85 + 2.017 1.954 -0.212
ENSG00000164338 E016 161.5220980 0.0002327211 3.639515e-02 8.433418e-02 5 73577856 73578005 150 + 2.149 2.117 -0.106
ENSG00000164338 E017 5.9110809 0.0887906839 2.054012e-01 3.329198e-01 5 73578006 73578416 411 + 0.829 0.618 -0.870
ENSG00000164338 E018 131.3254685 0.0010555386 3.561994e-01 5.005928e-01 5 73578751 73578852 102 + 2.052 2.053 0.004
ENSG00000164338 E019 123.0772242 0.0003098988 6.071727e-01 7.272138e-01 5 73579017 73579150 134 + 2.012 2.068 0.187
ENSG00000164338 E020 69.0470643 0.0036482776 1.565360e-01 2.704884e-01 5 73579317 73579375 59 + 1.750 1.865 0.389
ENSG00000164338 E021 447.8865858 0.0043068660 6.439642e-10 9.902361e-09 5 73579877 73583380 3504 + 2.521 2.740 0.731