ENSG00000164307

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000443439 ENSG00000164307 HEK293_OSMI2_2hA HEK293_TMG_2hB ERAP1 protein_coding protein_coding 1.857636 1.122133 3.172568 0.0100607 0.08642394 1.491148 1.69241924 1.02011252 2.986518 0.05366914 0.06771327 1.540485 0.91390833 0.90916667 0.9417333 0.03256667 0.81344417 0.03201909 FALSE  
ENST00000507859 ENSG00000164307 HEK293_OSMI2_2hA HEK293_TMG_2hB ERAP1 protein_coding retained_intron 1.857636 1.122133 3.172568 0.0100607 0.08642394 1.491148 0.03367321 0.08959273 0.000000 0.05016016 0.00000000 -3.316040 0.01564583 0.07983333 0.0000000 -0.07983333 0.03201909 0.03201909 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000164307 E001 5.3873950 0.0181384934 0.0270250929 0.066049445 5 96760810 96763228 2419 - 0.859 0.501 -1.518
ENSG00000164307 E002 72.2759396 0.0130264227 0.0036813770 0.012242414 5 96774484 96775916 1433 - 1.761 1.953 0.647
ENSG00000164307 E003 25.3050362 0.0010579208 0.2645423205 0.402505373 5 96775917 96776194 278 - 1.354 1.450 0.333
ENSG00000164307 E004 15.4837529 0.0121370461 0.2624631085 0.400251540 5 96776195 96776403 209 - 1.147 1.276 0.456
ENSG00000164307 E005 15.1182613 0.0028893868 0.0077074780 0.023044341 5 96776404 96776551 148 - 1.082 1.336 0.899
ENSG00000164307 E006 16.1208031 0.0050249739 0.0202935970 0.052097147 5 96780423 96780504 82 - 1.122 1.346 0.791
ENSG00000164307 E007 18.6726802 0.0058050213 0.5196035760 0.653680903 5 96781058 96781198 141 - 1.239 1.313 0.260
ENSG00000164307 E008 7.8947130 0.0306694938 0.5902971869 0.713178988 5 96781693 96781693 1 - 0.892 0.985 0.350
ENSG00000164307 E009 16.4792106 0.0086447178 0.7987899337 0.871616748 5 96781694 96781854 161 - 1.198 1.238 0.143
ENSG00000164307 E010 21.1145576 0.0010034818 0.1191977171 0.218786877 5 96783051 96783235 185 - 1.339 1.225 -0.399
ENSG00000164307 E011 23.9446650 0.0009885564 0.3843447935 0.528503383 5 96783924 96784080 157 - 1.376 1.325 -0.177
ENSG00000164307 E012 0.3697384 0.0258573172 0.0420311415 0.094777938 5 96785639 96785787 149 - 0.000 0.320 12.518
ENSG00000164307 E013 23.3310675 0.0008129878 0.7576031826 0.842360831 5 96785788 96785971 184 - 1.354 1.347 -0.025
ENSG00000164307 E014 15.1240360 0.0308930018 0.8057057100 0.876487411 5 96786470 96786549 80 - 1.160 1.197 0.133
ENSG00000164307 E015 0.0000000       5 96786658 96786760 103 -      
ENSG00000164307 E016 22.2994438 0.0153943601 0.7025210582 0.801334892 5 96788531 96788685 155 - 1.315 1.368 0.184
ENSG00000164307 E017 14.4765109 0.0220987879 0.9516697602 0.973730016 5 96790296 96790367 72 - 1.148 1.165 0.062
ENSG00000164307 E018 15.5557361 0.0050914729 0.3372981508 0.481169974 5 96790512 96790584 73 - 1.147 1.253 0.374
ENSG00000164307 E019 13.8985483 0.0263155242 0.6296062016 0.744958229 5 96790585 96790643 59 - 1.122 1.193 0.254
ENSG00000164307 E020 20.7497724 0.0010639977 0.8401253581 0.900165876 5 96792061 96792192 132 - 1.302 1.302 -0.001
ENSG00000164307 E021 17.8272398 0.0011688430 0.0062205808 0.019194892 5 96793400 96793513 114 - 1.298 1.055 -0.868
ENSG00000164307 E022 0.0000000       5 96793514 96793671 158 -      
ENSG00000164307 E023 18.7748898 0.0010530057 0.0003155661 0.001443092 5 96793803 96793957 155 - 1.339 1.011 -1.170
ENSG00000164307 E024 14.4930604 0.0071600493 0.1298153303 0.233901609 5 96795042 96795162 121 - 1.198 1.054 -0.518
ENSG00000164307 E025 8.9149918 0.0020672910 0.2287249628 0.360922379 5 96797175 96797246 72 - 1.006 0.877 -0.487
ENSG00000164307 E026 7.1382121 0.0029644880 0.5596983015 0.687782389 5 96797247 96797309 63 - 0.903 0.844 -0.228
ENSG00000164307 E027 9.2368105 0.1074919375 0.4002628634 0.543956318 5 96800862 96800933 72 - 1.007 0.905 -0.380
ENSG00000164307 E028 11.2536066 0.0488654087 0.9937916946 1.000000000 5 96800934 96801000 67 - 1.046 1.075 0.105
ENSG00000164307 E029 15.6626753 0.0072220166 0.0582856839 0.123685779 5 96803403 96803539 137 - 1.234 1.055 -0.643
ENSG00000164307 E030 25.5995716 0.0007484874 0.0156496151 0.041956507 5 96803540 96803827 288 - 1.436 1.265 -0.593
ENSG00000164307 E031 11.9689755 0.0014856062 0.2802561901 0.420101552 5 96803828 96803939 112 - 1.110 1.011 -0.360
ENSG00000164307 E032 4.1382239 0.0042084382 0.8880901499 0.932472508 5 96803940 96803943 4 - 0.689 0.682 -0.031
ENSG00000164307 E033 0.1817044 0.0390027041 0.1742133244   5 96804821 96804940 120 - 0.000 0.189 11.519
ENSG00000164307 E034 9.2835722 0.0030152574 0.2998083431 0.441397114 5 96807860 96808100 241 - 1.015 0.907 -0.402