ENSG00000164114

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000311277 ENSG00000164114 HEK293_OSMI2_2hA HEK293_TMG_2hB MAP9 protein_coding protein_coding 5.900392 0.9964375 10.67612 0.08345781 0.6963326 3.408408 1.97206872 0.52607452 3.4555164 0.06947353 0.2770100 2.6925649 0.34956667 0.53250000 0.32333333 -0.209166667 5.766320e-02 1.560469e-07 FALSE TRUE
ENST00000433024 ENSG00000164114 HEK293_OSMI2_2hA HEK293_TMG_2hB MAP9 protein_coding protein_coding 5.900392 0.9964375 10.67612 0.08345781 0.6963326 3.408408 1.27001055 0.08756321 0.8741833 0.08756321 0.4401868 3.1799363 0.18648333 0.07560000 0.08040000 0.004800000 8.884693e-01 1.560469e-07 FALSE TRUE
ENST00000515654 ENSG00000164114 HEK293_OSMI2_2hA HEK293_TMG_2hB MAP9 protein_coding protein_coding 5.900392 0.9964375 10.67612 0.08345781 0.6963326 3.408408 0.23238886 0.05933622 0.7886328 0.05933622 0.4196325 3.5258512 0.05048333 0.06743333 0.07010000 0.002666667 9.105424e-01 1.560469e-07 FALSE TRUE
MSTRG.25631.3 ENSG00000164114 HEK293_OSMI2_2hA HEK293_TMG_2hB MAP9 protein_coding   5.900392 0.9964375 10.67612 0.08345781 0.6963326 3.408408 1.31892303 0.00000000 2.9944163 0.00000000 0.1587240 8.2309409 0.14765000 0.00000000 0.28456667 0.284566667 1.560469e-07 1.560469e-07 FALSE TRUE
MSTRG.25631.4 ENSG00000164114 HEK293_OSMI2_2hA HEK293_TMG_2hB MAP9 protein_coding   5.900392 0.9964375 10.67612 0.08345781 0.6963326 3.408408 0.07382137 0.15026416 0.2816367 0.07553452 0.1480584 0.8637207 0.03030417 0.16473333 0.02586667 -0.138866667 4.717663e-01 1.560469e-07 FALSE TRUE
MSTRG.25631.5 ENSG00000164114 HEK293_OSMI2_2hA HEK293_TMG_2hB MAP9 protein_coding   5.900392 0.9964375 10.67612 0.08345781 0.6963326 3.408408 0.80907307 0.10376701 1.9348775 0.10376701 0.1753163 4.0955252 0.16694583 0.08960000 0.18076667 0.091166667 4.444613e-01 1.560469e-07 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000164114 E001 1.0520752 0.2913135684 6.714314e-01 7.776528e-01 4 155342658 155342676 19 - 0.251 0.001 -9.310
ENSG00000164114 E002 78.4891227 0.0003997306 6.595774e-13 1.668291e-11 4 155342677 155344113 1437 - 1.658 2.002 1.161
ENSG00000164114 E003 261.7802800 0.0028556320 2.566071e-09 3.526803e-08 4 155344114 155347103 2990 - 2.262 1.999 -0.881
ENSG00000164114 E004 37.5379356 0.0008561154 6.539505e-01 7.642793e-01 4 155347104 155347528 425 - 1.414 1.361 -0.183
ENSG00000164114 E005 34.6743336 0.0007591544 9.281381e-05 4.882622e-04 4 155347529 155347740 212 - 1.326 1.614 0.992
ENSG00000164114 E006 31.9839474 0.0006910619 3.834047e-04 1.710465e-03 4 155347741 155347905 165 - 1.300 1.572 0.937
ENSG00000164114 E007 0.4772466 0.0221636611 1.716259e-02 4.530244e-02 4 155349671 155350239 569 - 0.046 0.464 4.106
ENSG00000164114 E008 27.6256041 0.0030679150 3.902423e-01 5.342282e-01 4 155352596 155352683 88 - 1.273 1.343 0.246
ENSG00000164114 E009 19.2338684 0.0151714754 9.160649e-01 9.509368e-01 4 155352684 155352728 45 - 1.134 1.129 -0.020
ENSG00000164114 E010 39.9549757 0.0083662262 9.444382e-01 9.691728e-01 4 155352912 155353057 146 - 1.437 1.413 -0.081
ENSG00000164114 E011 38.9094612 0.0006242734 8.309732e-01 8.940357e-01 4 155353179 155353252 74 - 1.423 1.428 0.017
ENSG00000164114 E012 44.8485264 0.0006155411 4.346759e-01 5.769858e-01 4 155353253 155353340 88 - 1.478 1.525 0.161
ENSG00000164114 E013 47.5899064 0.0005294386 6.854384e-01 7.881703e-01 4 155355071 155355160 90 - 1.507 1.525 0.060
ENSG00000164114 E014 53.8102337 0.0004218881 7.216899e-01 8.159730e-01 4 155355716 155355884 169 - 1.559 1.572 0.042
ENSG00000164114 E015 28.9628770 0.0007229991 5.089766e-01 6.443479e-01 4 155357449 155357519 71 - 1.293 1.343 0.175
ENSG00000164114 E016 49.5512240 0.0005037664 7.229207e-01 8.169076e-01 4 155360168 155360343 176 - 1.523 1.537 0.047
ENSG00000164114 E017 31.0923360 0.0006940426 4.863280e-01 6.240846e-01 4 155360344 155360415 72 - 1.341 1.260 -0.285
ENSG00000164114 E018 37.9697153 0.0006141684 3.311047e-01 4.746970e-01 4 155362048 155362141 94 - 1.425 1.324 -0.352
ENSG00000164114 E019 0.2966881 0.0274424043 1.000000e+00   4 155368166 155368585 420 - 0.087 0.000 -10.121
ENSG00000164114 E020 60.8151477 0.0004403838 3.251296e-01 4.685514e-01 4 155368586 155368809 224 - 1.621 1.537 -0.287
ENSG00000164114 E021 9.8532311 0.0020874611 2.602205e-01 3.976991e-01 4 155368810 155368812 3 - 0.890 0.683 -0.823
ENSG00000164114 E022 0.2987644 0.0278964571 1.000000e+00   4 155372996 155373135 140 - 0.087 0.000 -10.120
ENSG00000164114 E023 64.8964804 0.0032494740 2.373732e-01 3.711315e-01 4 155373136 155373456 321 - 1.652 1.549 -0.351
ENSG00000164114 E024 23.7113497 0.0008400508 1.574580e-01 2.717248e-01 4 155374937 155375003 67 - 1.241 1.061 -0.643
ENSG00000164114 E025 16.5044614 0.0169194825 7.357393e-01 8.264274e-01 4 155375004 155375021 18 - 1.083 1.022 -0.222
ENSG00000164114 E026 30.4419830 0.0030513050 4.186961e-01 5.619308e-01 4 155375776 155375870 95 - 1.333 1.236 -0.337
ENSG00000164114 E027 21.5542029 0.0008613558 8.594072e-01 9.133049e-01 4 155375871 155375914 44 - 1.178 1.186 0.026
ENSG00000164114 E028 10.9426692 0.0015244727 3.294494e-01 4.729598e-01 4 155376376 155376770 395 - 0.931 0.762 -0.658
ENSG00000164114 E029 14.6286361 0.0011663208 2.868375e-01 4.272859e-01 4 155376771 155376970 200 - 1.009 1.128 0.433