ENSG00000163788

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000296088 ENSG00000163788 HEK293_OSMI2_2hA HEK293_TMG_2hB SNRK protein_coding protein_coding 5.635544 2.809464 8.46416 0.2606586 0.1571605 1.587649 3.01568215 0.8292031 3.9541731 0.1438681 0.35461127 2.2399281 0.44913750 0.2910667 0.46856667 0.17750000 9.086430e-02 3.754902e-10 FALSE TRUE
ENST00000429705 ENSG00000163788 HEK293_OSMI2_2hA HEK293_TMG_2hB SNRK protein_coding protein_coding 5.635544 2.809464 8.46416 0.2606586 0.1571605 1.587649 0.62864755 0.0000000 0.9487385 0.0000000 0.07296021 6.5830655 0.09582917 0.0000000 0.11203333 0.11203333 2.776653e-08 3.754902e-10 FALSE TRUE
ENST00000437827 ENSG00000163788 HEK293_OSMI2_2hA HEK293_TMG_2hB SNRK protein_coding protein_coding 5.635544 2.809464 8.46416 0.2606586 0.1571605 1.587649 0.25368010 0.3949100 0.1617953 0.3949100 0.16179528 -1.2369108 0.07346667 0.1189000 0.01923333 -0.09966667 8.604569e-01 3.754902e-10 FALSE TRUE
ENST00000454177 ENSG00000163788 HEK293_OSMI2_2hA HEK293_TMG_2hB SNRK protein_coding protein_coding 5.635544 2.809464 8.46416 0.2606586 0.1571605 1.587649 0.30857007 0.0000000 0.9048025 0.0000000 0.13955850 6.5153885 0.04211667 0.0000000 0.10690000 0.10690000 9.634806e-07 3.754902e-10 FALSE TRUE
ENST00000481892 ENSG00000163788 HEK293_OSMI2_2hA HEK293_TMG_2hB SNRK protein_coding retained_intron 5.635544 2.809464 8.46416 0.2606586 0.1571605 1.587649 0.42093409 0.9280160 0.1048553 0.1643283 0.02579718 -3.0297945 0.13932083 0.3403333 0.01250000 -0.32783333 3.754902e-10 3.754902e-10 FALSE TRUE
MSTRG.22798.4 ENSG00000163788 HEK293_OSMI2_2hA HEK293_TMG_2hB SNRK protein_coding   5.635544 2.809464 8.46416 0.2606586 0.1571605 1.587649 0.65870173 0.3505934 1.8988379 0.3505934 0.96914277 2.4042496 0.12499583 0.1420000 0.22296667 0.08096667 6.323503e-01 3.754902e-10 FALSE TRUE
MSTRG.22798.5 ENSG00000163788 HEK293_OSMI2_2hA HEK293_TMG_2hB SNRK protein_coding   5.635544 2.809464 8.46416 0.2606586 0.1571605 1.587649 0.06623271 0.1872609 0.1239076 0.1872609 0.12390761 -0.5588672 0.01387083 0.0710000 0.01413333 -0.05686667 8.922678e-01 3.754902e-10 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000163788 E001 0.0000000       3 43286512 43286537 26 +      
ENSG00000163788 E002 0.0000000       3 43286538 43286539 2 +      
ENSG00000163788 E003 0.0000000       3 43286540 43286552 13 +      
ENSG00000163788 E004 2.9072273 0.2710459727 6.135764e-01 7.322356e-01 3 43286553 43286580 28 + 0.521 0.608 0.397
ENSG00000163788 E005 2.6041964 0.2019761471 5.118151e-01 6.467572e-01 3 43286581 43286583 3 + 0.471 0.607 0.636
ENSG00000163788 E006 2.9008845 0.1158961771 6.783545e-01 7.828569e-01 3 43286584 43286585 2 + 0.520 0.605 0.389
ENSG00000163788 E007 9.9210455 0.0025846938 4.657357e-02 1.030714e-01 3 43286586 43286675 90 + 1.038 0.805 -0.880
ENSG00000163788 E008 2.5099173 0.0078224574 4.710124e-03 1.512461e-02 3 43289740 43289789 50 + 0.603 0.000 -12.793
ENSG00000163788 E009 11.7116696 0.0059344745 9.119538e-03 2.658198e-02 3 43299754 43299815 62 + 1.115 0.805 -1.161
ENSG00000163788 E010 9.9964908 0.0016726320 1.950438e-03 7.072943e-03 3 43303098 43303111 14 + 1.065 0.662 -1.565
ENSG00000163788 E011 24.7730675 0.0008003754 1.939551e-04 9.379984e-04 3 43303112 43303223 112 + 1.420 1.113 -1.081
ENSG00000163788 E012 67.1560844 0.0111760126 1.024013e-05 6.790684e-05 3 43303224 43303616 393 + 1.843 1.537 -1.038
ENSG00000163788 E013 43.2991839 0.0019491683 1.596317e-03 5.949235e-03 3 43303617 43303792 176 + 1.635 1.446 -0.645
ENSG00000163788 E014 0.1451727 0.0428084086 1.000000e+00   3 43332166 43332168 3 + 0.071 0.000 -8.520
ENSG00000163788 E015 39.8571078 0.0051235598 6.024247e-03 1.867606e-02 3 43332169 43332310 142 + 1.599 1.417 -0.624
ENSG00000163788 E016 0.0000000       3 43332311 43333390 1080 +      
ENSG00000163788 E017 54.1257763 0.0020590063 1.148979e-02 3.232795e-02 3 43340287 43340499 213 + 1.719 1.594 -0.423
ENSG00000163788 E018 1.9292360 0.0096254308 1.829213e-01 3.048532e-01 3 43340500 43340681 182 + 0.350 0.601 1.271
ENSG00000163788 E019 0.4439371 0.0215871746 4.718313e-01 6.109176e-01 3 43343236 43343343 108 + 0.185 0.000 -10.295
ENSG00000163788 E020 21.3382881 0.0009100749 9.706601e-03 2.803874e-02 3 43343344 43343350 7 + 1.344 1.132 -0.745
ENSG00000163788 E021 43.9526482 0.0006372399 3.936372e-03 1.296230e-02 3 43343351 43343478 128 + 1.638 1.482 -0.535
ENSG00000163788 E022 552.7936663 0.0011460649 6.064495e-26 7.221246e-24 3 43347339 43351425 4087 + 2.647 2.791 0.478
ENSG00000163788 E023 0.0000000       3 43361767 43361868 102 +      
ENSG00000163788 E024 0.0000000       3 43424525 43424764 240 +