ENSG00000163320

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000309534 ENSG00000163320 HEK293_OSMI2_2hA HEK293_TMG_2hB CGGBP1 protein_coding protein_coding 52.30656 23.27475 86.6567 0.6416044 2.225915 1.896092 15.655299 6.5591090 29.062295 1.0437305 0.6189342 2.1458754 0.26315833 0.27976667 0.3360333 0.05626667 5.729005e-01 9.161571e-07 FALSE TRUE
ENST00000462901 ENSG00000163320 HEK293_OSMI2_2hA HEK293_TMG_2hB CGGBP1 protein_coding protein_coding 52.30656 23.27475 86.6567 0.6416044 2.225915 1.896092 6.566323 1.5044860 11.558928 0.6586510 0.2942610 2.9333551 0.11313333 0.06326667 0.1334000 0.07013333 2.847831e-01 9.161571e-07 FALSE TRUE
ENST00000474441 ENSG00000163320 HEK293_OSMI2_2hA HEK293_TMG_2hB CGGBP1 protein_coding processed_transcript 52.30656 23.27475 86.6567 0.6416044 2.225915 1.896092 3.739201 0.5308419 6.966210 0.2727108 0.6218518 3.6891647 0.06644167 0.02286667 0.0805000 0.05763333 1.235392e-01 9.161571e-07   FALSE
ENST00000482016 ENSG00000163320 HEK293_OSMI2_2hA HEK293_TMG_2hB CGGBP1 protein_coding protein_coding 52.30656 23.27475 86.6567 0.6416044 2.225915 1.896092 5.492793 2.0627285 9.677313 0.1362703 1.3196553 2.2245654 0.10072917 0.08873333 0.1114333 0.02270000 6.079368e-01 9.161571e-07 FALSE TRUE
ENST00000675130 ENSG00000163320 HEK293_OSMI2_2hA HEK293_TMG_2hB CGGBP1 protein_coding protein_coding 52.30656 23.27475 86.6567 0.6416044 2.225915 1.896092 13.676479 11.4429750 16.365439 0.9548591 1.3478911 0.5158112 0.35337083 0.49470000 0.1883333 -0.30636667 6.294173e-06 9.161571e-07 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000163320 E001 0.000000       3 88051944 88051949 6 -      
ENSG00000163320 E002 1.176983 0.0108647759 2.605570e-04 1.218959e-03 3 88051950 88052011 62 - 0.071 0.663 4.351
ENSG00000163320 E003 2242.228251 0.0105808441 4.805739e-03 1.539011e-02 3 88052012 88055322 3311 - 3.327 3.192 -0.447
ENSG00000163320 E004 179.675096 0.0058460323 8.365534e-12 1.763857e-10 3 88055323 88055425 103 - 2.279 1.853 -1.427
ENSG00000163320 E005 499.731830 0.0011280843 3.696341e-03 1.228506e-02 3 88055426 88055657 232 - 2.641 2.653 0.039
ENSG00000163320 E006 725.917305 0.0003519634 7.067383e-27 9.010057e-25 3 88055658 88055999 342 - 2.774 2.887 0.375
ENSG00000163320 E007 69.579719 0.0057275400 8.162128e-10 1.229752e-08 3 88056000 88057190 1191 - 1.881 1.376 -1.721
ENSG00000163320 E008 58.938415 0.0023412739 2.258789e-01 3.574407e-01 3 88057191 88057292 102 - 1.754 1.627 -0.429
ENSG00000163320 E009 5.809563 0.0748589649 5.254027e-03 1.662177e-02 3 88057293 88057309 17 - 0.887 0.204 -3.480
ENSG00000163320 E010 34.173775 0.0049177536 5.165118e-09 6.721039e-08 3 88057638 88058018 381 - 1.588 0.945 -2.273
ENSG00000163320 E011 416.192366 0.0008555511 9.444008e-08 9.630417e-07 3 88058019 88058138 120 - 2.546 2.614 0.225
ENSG00000163320 E012 319.359673 0.0008414987 3.695737e-03 1.228348e-02 3 88058139 88058223 85 - 2.444 2.466 0.071
ENSG00000163320 E013 5.026289 0.0032556567 7.491869e-02 1.513981e-01 3 88058373 88058451 79 - 0.799 0.447 -1.554
ENSG00000163320 E014 217.940478 0.0052596994 2.469915e-03 8.673632e-03 3 88058815 88059048 234 - 2.264 2.337 0.243
ENSG00000163320 E015 54.137892 0.0004486290 1.060899e-06 8.755571e-06 3 88140970 88141078 109 - 1.759 1.388 -1.270
ENSG00000163320 E016 6.557405 0.0550125444 8.202607e-01 8.865987e-01 3 88149300 88149567 268 - 0.822 0.814 -0.033
ENSG00000163320 E017 13.106118 0.0093190797 9.154092e-01 9.504685e-01 3 88149568 88149710 143 - 1.113 1.050 -0.231
ENSG00000163320 E018 23.050137 0.0008509589 3.081164e-02 7.354846e-02 3 88149711 88149885 175 - 1.382 1.134 -0.874