ENSG00000160310

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000291705 ENSG00000160310 HEK293_OSMI2_2hA HEK293_TMG_2hB PRMT2 protein_coding protein_coding 71.01375 78.69818 65.22325 2.894571 1.756934 -0.270906 5.145271 7.336194 5.340400 1.7129963 0.1788335 -0.4573503 0.07182083 0.09226667 0.08190000 -0.01036667 9.128157e-01 2.589425e-05 FALSE  
ENST00000355680 ENSG00000160310 HEK293_OSMI2_2hA HEK293_TMG_2hB PRMT2 protein_coding protein_coding 71.01375 78.69818 65.22325 2.894571 1.756934 -0.270906 7.113551 7.065445 10.301630 0.7351672 1.3980261 0.5433797 0.10220000 0.08943333 0.15920000 0.06976667 6.801014e-02 2.589425e-05 FALSE  
ENST00000397628 ENSG00000160310 HEK293_OSMI2_2hA HEK293_TMG_2hB PRMT2 protein_coding protein_coding 71.01375 78.69818 65.22325 2.894571 1.756934 -0.270906 22.955102 31.803144 17.794200 1.4380132 2.6637914 -0.8374054 0.31893750 0.40640000 0.27103333 -0.13536667 9.784150e-02 2.589425e-05 FALSE  
ENST00000397638 ENSG00000160310 HEK293_OSMI2_2hA HEK293_TMG_2hB PRMT2 protein_coding protein_coding 71.01375 78.69818 65.22325 2.894571 1.756934 -0.270906 9.967403 12.103507 6.049525 1.4150743 1.4926233 -0.9993400 0.13905833 0.15320000 0.09193333 -0.06126667 2.748288e-01 2.589425e-05 FALSE  
ENST00000481861 ENSG00000160310 HEK293_OSMI2_2hA HEK293_TMG_2hB PRMT2 protein_coding retained_intron 71.01375 78.69818 65.22325 2.894571 1.756934 -0.270906 13.018304 8.825208 12.190550 0.1530007 0.3930248 0.4656101 0.18536667 0.11233333 0.18746667 0.07513333 2.589425e-05 2.589425e-05 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000160310 E001 0.6017953 0.1783944256 3.415910e-02 8.006902e-02 21 46635501 46635594 94 + 0.400 0.000 -12.143
ENSG00000160310 E002 0.5954526 0.0184660432 1.835716e-02 4.791619e-02 21 46635595 46635614 20 + 0.400 0.000 -12.169
ENSG00000160310 E003 2.2560139 0.0155578725 6.794744e-02 1.399619e-01 21 46635615 46635641 27 + 0.679 0.380 -1.433
ENSG00000160310 E004 4.9778419 0.0032268015 7.754743e-01 8.553488e-01 21 46635642 46635649 8 + 0.743 0.782 0.157
ENSG00000160310 E005 5.3047190 0.0030437541 8.220655e-01 8.877967e-01 21 46635650 46635652 3 + 0.771 0.801 0.119
ENSG00000160310 E006 27.5053539 0.0007386167 5.932604e-05 3.280926e-04 21 46635653 46635673 21 + 1.588 1.326 -0.902
ENSG00000160310 E007 53.1963377 0.0117308047 3.062656e-02 7.318966e-02 21 46635674 46635680 7 + 1.812 1.652 -0.541
ENSG00000160310 E008 300.4543047 0.0017821573 9.129696e-03 2.660708e-02 21 46635681 46635763 83 + 2.513 2.436 -0.258
ENSG00000160310 E009 7.1778486 0.0023907223 2.387017e-03 8.420474e-03 21 46635764 46636438 675 + 1.091 0.739 -1.336
ENSG00000160310 E010 86.3264365 0.0098830256 4.432359e-09 5.831857e-08 21 46636439 46636547 109 + 2.118 1.758 -1.212
ENSG00000160310 E011 445.1718193 0.0001953533 7.197017e-03 2.173769e-02 21 46636896 46636990 95 + 2.668 2.621 -0.156
ENSG00000160310 E012 1.8853556 0.0280557234 2.981802e-01 4.395922e-01 21 46643286 46643531 246 + 0.562 0.380 -0.917
ENSG00000160310 E013 9.7111487 0.0035413802 2.242231e-01 3.554737e-01 21 46643532 46643534 3 + 1.091 0.961 -0.476
ENSG00000160310 E014 439.8235158 0.0010112431 2.107176e-01 3.393936e-01 21 46643535 46643639 105 + 2.618 2.642 0.083
ENSG00000160310 E015 220.5265768 0.0042948440 5.558712e-01 6.846593e-01 21 46644306 46644310 5 + 2.321 2.339 0.060
ENSG00000160310 E016 287.2828899 0.0009955463 8.937450e-02 1.741733e-01 21 46644311 46644342 32 + 2.423 2.464 0.138
ENSG00000160310 E017 580.1967826 0.0001597414 6.322082e-07 5.480960e-06 21 46644343 46644488 146 + 2.705 2.782 0.255
ENSG00000160310 E018 1.4446276 0.0112778159 4.425592e-01 5.841678e-01 21 46648318 46648457 140 + 0.461 0.327 -0.751
ENSG00000160310 E019 434.4505997 0.0008677426 1.083042e-03 4.246254e-03 21 46648458 46648507 50 + 2.584 2.654 0.232
ENSG00000160310 E020 611.4905156 0.0016155164 8.776480e-05 4.645649e-04 21 46648508 46648619 112 + 2.719 2.808 0.295
ENSG00000160310 E021 3.7065102 0.0047655915 5.527900e-03 1.735975e-02 21 46649513 46649574 62 + 0.329 0.782 2.158
ENSG00000160310 E022 641.3631558 0.0012724524 4.610596e-05 2.620495e-04 21 46649575 46649739 165 + 2.743 2.827 0.280
ENSG00000160310 E023 39.6437874 0.0006025847 2.760324e-03 9.553069e-03 21 46649740 46649893 154 + 1.478 1.654 0.600
ENSG00000160310 E024 15.7491921 0.0115048730 2.715270e-13 7.261431e-12 21 46651806 46652318 513 + 1.525 0.761 -2.768
ENSG00000160310 E025 25.8132813 0.0007415212 2.076632e-05 1.283227e-04 21 46652845 46653121 277 + 1.571 1.284 -0.991
ENSG00000160310 E026 85.6152490 0.0406435943 1.129079e-05 7.411150e-05 21 46656823 46658744 1922 + 2.152 1.681 -1.587
ENSG00000160310 E027 292.8129177 0.0001909995 1.576005e-07 1.541083e-06 21 46658745 46658920 176 + 2.524 2.414 -0.365
ENSG00000160310 E028 170.8768373 0.0063337551 1.093338e-06 9.001332e-06 21 46658921 46659430 510 + 2.351 2.118 -0.778
ENSG00000160310 E029 213.8528568 0.0019620354 1.398099e-01 2.477649e-01 21 46660833 46660962 130 + 2.352 2.305 -0.158
ENSG00000160310 E030 60.3611597 0.0053258775 6.482059e-04 2.709755e-03 21 46660963 46661799 837 + 1.888 1.695 -0.651
ENSG00000160310 E031 167.4789838 0.0052528981 1.722910e-01 2.911947e-01 21 46661800 46661936 137 + 2.178 2.240 0.207
ENSG00000160310 E032 262.6589675 0.0002143545 1.463116e-01 2.566584e-01 21 46663383 46663554 172 + 2.393 2.426 0.112
ENSG00000160310 E033 642.8477016 0.0037976624 3.844308e-01 5.285761e-01 21 46664295 46665124 830 + 2.780 2.808 0.093