ENSG00000158163

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000327532 ENSG00000158163 HEK293_OSMI2_2hA HEK293_TMG_2hB DZIP1L protein_coding protein_coding 4.224248 3.915616 4.13655 0.2235737 0.216749 0.07899256 1.9602794 2.41216527 1.80930754 0.14967757 0.131302205 -0.41290787 0.47568750 0.61613333 0.44066667 -0.17546667 0.03640626 0.03640626 FALSE TRUE
ENST00000473850 ENSG00000158163 HEK293_OSMI2_2hA HEK293_TMG_2hB DZIP1L protein_coding retained_intron 4.224248 3.915616 4.13655 0.2235737 0.216749 0.07899256 0.2568838 0.04606337 0.10675372 0.04606337 0.002796121 1.05833820 0.05583750 0.01313333 0.02586667 0.01273333 0.61907295 0.03640626   FALSE
ENST00000486487 ENSG00000158163 HEK293_OSMI2_2hA HEK293_TMG_2hB DZIP1L protein_coding protein_coding 4.224248 3.915616 4.13655 0.2235737 0.216749 0.07899256 0.2533470 0.17280716 0.04522553 0.17280716 0.045225533 -1.72691524 0.05599167 0.04040000 0.01020000 -0.03020000 0.96983130 0.03640626 FALSE TRUE
ENST00000488595 ENSG00000158163 HEK293_OSMI2_2hA HEK293_TMG_2hB DZIP1L protein_coding processed_transcript 4.224248 3.915616 4.13655 0.2235737 0.216749 0.07899256 0.3726097 0.41513150 0.41142369 0.03486253 0.321248466 -0.01263777 0.08676250 0.10773333 0.09326667 -0.01446667 0.71482449 0.03640626 FALSE FALSE
ENST00000492010 ENSG00000158163 HEK293_OSMI2_2hA HEK293_TMG_2hB DZIP1L protein_coding protein_coding 4.224248 3.915616 4.13655 0.2235737 0.216749 0.07899256 0.4498004 0.42902665 0.56745227 0.07377668 0.183775970 0.39539318 0.10535417 0.10806667 0.13316667 0.02510000 0.88631884 0.03640626 TRUE FALSE
MSTRG.23776.3 ENSG00000158163 HEK293_OSMI2_2hA HEK293_TMG_2hB DZIP1L protein_coding   4.224248 3.915616 4.13655 0.2235737 0.216749 0.07899256 0.5466678 0.31679283 0.79646669 0.08581450 0.181816241 1.30323861 0.12883333 0.08296667 0.19846667 0.11550000 0.22213104 0.03640626 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000158163 E001 54.3719023 0.0087526513 0.020195182 0.051893018 3 138061990 138062589 600 - 1.638 1.786 0.503
ENSG00000158163 E002 25.2024142 0.0036313746 0.126021530 0.228603171 3 138062590 138062687 98 - 1.332 1.447 0.397
ENSG00000158163 E003 39.5885239 0.0005966522 0.015942699 0.042604194 3 138062688 138062977 290 - 1.511 1.648 0.465
ENSG00000158163 E004 0.8385790 0.0175364683 0.265638311 0.403709286 3 138064403 138064627 225 - 0.135 0.334 1.662
ENSG00000158163 E005 31.6570820 0.0050315012 0.294205647 0.435301015 3 138064628 138064767 140 - 1.460 1.535 0.258
ENSG00000158163 E006 29.0915833 0.0062424836 0.227108377 0.358945487 3 138067531 138067700 170 - 1.413 1.505 0.315
ENSG00000158163 E007 22.4179702 0.0009006728 0.545571002 0.675879139 3 138068151 138068300 150 - 1.332 1.378 0.159
ENSG00000158163 E008 17.6553209 0.0011968010 0.867859277 0.919013407 3 138068301 138068367 67 - 1.269 1.257 -0.040
ENSG00000158163 E009 0.7728880 0.0155421102 0.061641811 0.129387361 3 138068983 138069164 182 - 0.000 0.334 10.049
ENSG00000158163 E010 23.2603878 0.0009368951 0.226595152 0.358339637 3 138071643 138071835 193 - 1.325 1.413 0.307
ENSG00000158163 E011 27.3330966 0.0224822931 0.586261335 0.709861448 3 138077499 138077632 134 - 1.413 1.468 0.190
ENSG00000158163 E012 0.0000000       3 138080349 138080566 218 -      
ENSG00000158163 E013 17.4097880 0.0014034995 0.805602605 0.876405443 3 138080567 138080620 54 - 1.242 1.264 0.078
ENSG00000158163 E014 16.5681147 0.0011436347 0.849850856 0.906816797 3 138081734 138081764 31 - 1.242 1.229 -0.048
ENSG00000158163 E015 0.3729606 0.0271447926 0.863696276 0.916110524 3 138081765 138081829 65 - 0.135 0.111 -0.335
ENSG00000158163 E016 25.8963840 0.0008876066 0.445637660 0.587196178 3 138084113 138084253 141 - 1.388 1.441 0.186
ENSG00000158163 E017 16.6066461 0.0011610287 0.415106931 0.558528144 3 138086961 138086973 13 - 1.194 1.264 0.247
ENSG00000158163 E018 20.4541669 0.0011970953 0.448429257 0.589721967 3 138086974 138087023 50 - 1.285 1.345 0.209
ENSG00000158163 E019 25.2337083 0.0087436861 0.507212724 0.642802195 3 138088379 138088507 129 - 1.436 1.385 -0.179
ENSG00000158163 E020 1.5187246 0.0121644995 0.317610286 0.460500033 3 138088508 138088900 393 - 0.504 0.334 -0.926
ENSG00000158163 E021 0.0000000       3 138092352 138092382 31 -      
ENSG00000158163 E022 24.8890221 0.0061857146 0.001445463 0.005457889 3 138092383 138092544 162 - 1.526 1.286 -0.829
ENSG00000158163 E023 20.9773347 0.0040919065 0.001946565 0.007061061 3 138094862 138094983 122 - 1.460 1.221 -0.831
ENSG00000158163 E024 15.2081371 0.0325256590 0.181503947 0.303129597 3 138097763 138097847 85 - 1.294 1.140 -0.542
ENSG00000158163 E025 23.6982193 0.0009006728 0.011751401 0.032938314 3 138103471 138103770 300 - 1.476 1.303 -0.597
ENSG00000158163 E026 13.0076826 0.0013776021 0.051147768 0.111209458 3 138103771 138103853 83 - 1.233 1.058 -0.627
ENSG00000158163 E027 23.1595432 0.0044658366 0.107719671 0.202170177 3 138103854 138104052 199 - 1.437 1.317 -0.416
ENSG00000158163 E028 8.0567928 0.0069743025 0.082284205 0.163116728 3 138112364 138112500 137 - 1.051 0.851 -0.749
ENSG00000158163 E029 0.0000000       3 138113389 138113480 92 -      
ENSG00000158163 E030 0.0000000       3 138114939 138115327 389 -      
ENSG00000158163 E031 15.5496288 0.0357819786 0.613223443 0.731980402 3 138115328 138115459 132 - 1.233 1.182 -0.181
ENSG00000158163 E032 16.2158940 0.0083771195 0.601872902 0.722931064 3 138115460 138115818 359 - 1.251 1.206 -0.157