ENSG00000156802

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000287394 ENSG00000156802 HEK293_OSMI2_2hA HEK293_TMG_2hB ATAD2 protein_coding protein_coding 17.60295 2.7616 29.54461 0.1415226 0.5807998 3.414592 9.353553 2.61253531 15.46881 0.16260866 0.2616684 2.561260 0.6786333 0.9452 0.5238333 -0.4213667 1.196251e-21 1.000813e-21 FALSE TRUE
MSTRG.32048.5 ENSG00000156802 HEK293_OSMI2_2hA HEK293_TMG_2hB ATAD2 protein_coding   17.60295 2.7616 29.54461 0.1415226 0.5807998 3.414592 7.881530 0.04451915 13.45255 0.04451915 0.4827514 7.947973 0.2848417 0.0168 0.4550667 0.4382667 1.000813e-21 1.000813e-21 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000156802 E001 57.3450398 0.0132432420 4.974566e-12 1.088492e-10 8 123319850 123320501 652 - 1.455 2.026 1.934
ENSG00000156802 E002 111.5356951 0.0104339295 1.642641e-15 6.036729e-14 8 123320502 123320680 179 - 1.747 2.285 1.804
ENSG00000156802 E003 132.7260764 0.0130287512 1.934023e-14 6.107599e-13 8 123320681 123320911 231 - 1.820 2.363 1.818
ENSG00000156802 E004 116.0982897 0.0002428909 6.754487e-13 1.704565e-11 8 123320912 123321175 264 - 1.810 2.162 1.183
ENSG00000156802 E005 116.5308074 0.0003733216 1.695970e-06 1.340299e-05 8 123322938 123323066 129 - 1.829 2.089 0.874
ENSG00000156802 E006 134.4356189 0.0002634760 3.820070e-06 2.791948e-05 8 123325893 123326026 134 - 1.894 2.134 0.804
ENSG00000156802 E007 279.8311339 0.0010912765 9.894214e-04 3.922220e-03 8 123328190 123328579 390 - 2.223 2.376 0.512
ENSG00000156802 E008 160.2075362 0.0045223644 1.626268e-01 2.785779e-01 8 123333878 123334021 144 - 1.986 2.104 0.394
ENSG00000156802 E009 129.0830410 0.0117337797 3.216454e-01 4.648988e-01 8 123334200 123334322 123 - 1.894 2.013 0.400
ENSG00000156802 E010 151.1622335 0.0023850745 3.656490e-02 8.464883e-02 8 123336373 123336532 160 - 1.959 2.101 0.478
ENSG00000156802 E011 154.9382080 0.0002426401 2.256135e-01 3.571250e-01 8 123337625 123337821 197 - 1.976 2.071 0.317
ENSG00000156802 E012 117.9731691 0.0005760739 8.745564e-01 9.233423e-01 8 123339311 123339446 136 - 1.868 1.902 0.114
ENSG00000156802 E013 0.8868421 0.0378423061 6.062991e-01 7.264936e-01 8 123344513 123344883 371 - 0.181 0.306 0.981
ENSG00000156802 E014 130.2066774 0.0002667169 3.155157e-01 4.582861e-01 8 123344884 123345069 186 - 1.916 1.908 -0.027
ENSG00000156802 E015 136.0424175 0.0019803111 1.248495e-01 2.269108e-01 8 123346086 123346272 187 - 1.937 1.897 -0.137
ENSG00000156802 E016 110.4831426 0.0011164556 2.956740e-02 7.110793e-02 8 123346618 123346750 133 - 1.852 1.766 -0.289
ENSG00000156802 E017 188.7793394 0.0013808142 1.407166e-05 9.030911e-05 8 123347092 123347406 315 - 2.089 1.919 -0.571
ENSG00000156802 E018 50.7951907 0.0016355423 1.436944e-02 3.906728e-02 8 123348183 123348186 4 - 1.529 1.352 -0.610
ENSG00000156802 E019 91.5085224 0.0009024705 9.360668e-05 4.919687e-04 8 123348187 123348273 87 - 1.783 1.554 -0.776
ENSG00000156802 E020 121.0167425 0.0002891712 6.078508e-05 3.353198e-04 8 123349285 123349421 137 - 1.899 1.709 -0.643
ENSG00000156802 E021 61.0170735 0.0008274371 4.580756e-02 1.016791e-01 8 123349422 123349444 23 - 1.601 1.487 -0.390
ENSG00000156802 E022 0.4439371 0.0215601949 1.000000e+00 1.000000e+00 8 123356100 123356388 289 - 0.117 0.000 -8.846
ENSG00000156802 E023 96.1246803 0.0002990001 5.390455e-03 1.698889e-02 8 123356389 123356477 89 - 1.796 1.663 -0.449
ENSG00000156802 E024 119.5800490 0.0014030536 9.740862e-02 1.865223e-01 8 123357562 123357736 175 - 1.882 1.830 -0.174
ENSG00000156802 E025 43.9741635 0.0011886460 2.169845e-01 3.467721e-01 8 123359221 123359243 23 - 1.458 1.390 -0.236
ENSG00000156802 E026 79.3319899 0.0003054675 1.434409e-01 2.526986e-01 8 123359244 123359336 93 - 1.707 1.653 -0.183
ENSG00000156802 E027 85.5397467 0.0004831345 5.220872e-04 2.242372e-03 8 123359577 123359685 109 - 1.753 1.554 -0.675
ENSG00000156802 E028 94.8022862 0.0003258487 6.390615e-08 6.739870e-07 8 123361539 123361646 108 - 1.805 1.457 -1.184
ENSG00000156802 E029 109.1438273 0.0002503782 8.689883e-08 8.926272e-07 8 123369058 123369175 118 - 1.863 1.554 -1.047
ENSG00000156802 E030 0.0000000       8 123369273 123369388 116 -      
ENSG00000156802 E031 143.7276558 0.0002546600 1.152489e-08 1.405353e-07 8 123369821 123370022 202 - 1.979 1.700 -0.940
ENSG00000156802 E032 52.9884435 0.0009403132 1.492718e-04 7.438733e-04 8 123370023 123370024 2 - 1.556 1.240 -1.095
ENSG00000156802 E033 110.2547696 0.0002669606 7.139826e-07 6.120447e-06 8 123370903 123370990 88 - 1.865 1.590 -0.931
ENSG00000156802 E034 121.2580628 0.0002609346 4.405412e-08 4.802302e-07 8 123371236 123371338 103 - 1.908 1.612 -1.001
ENSG00000156802 E035 139.0884495 0.0002784300 6.496348e-11 1.181901e-09 8 123371670 123371835 166 - 1.970 1.623 -1.173
ENSG00000156802 E036 63.9156715 0.0005268956 4.771006e-04 2.072439e-03 8 123372637 123372661 25 - 1.634 1.390 -0.836
ENSG00000156802 E037 58.4953612 0.0010777734 3.399559e-03 1.143632e-02 8 123372662 123372686 25 - 1.594 1.390 -0.702
ENSG00000156802 E038 91.5555661 0.0002959513 1.229934e-04 6.275952e-04 8 123380529 123380677 149 - 1.783 1.566 -0.737
ENSG00000156802 E039 0.1451727 0.0430553854 6.332933e-01   8 123380678 123380914 237 - 0.043 0.000 -7.260
ENSG00000156802 E040 0.0000000       8 123396183 123396186 4 -      
ENSG00000156802 E041 63.8668919 0.0003818472 2.101019e-03 7.537142e-03 8 123396187 123396447 261 - 1.628 1.425 -0.698
ENSG00000156802 E042 0.7490443 0.0868611244 1.000000e+00 1.000000e+00 8 123400743 123401175 433 - 0.181 0.000 -9.585
ENSG00000156802 E043 2.3364761 0.3590531594 2.810966e-03 9.707231e-03 8 123412080 123412177 98 - 0.182 1.026 4.206
ENSG00000156802 E044 2.4022544 0.2677968006 1.928407e-03 7.003371e-03 8 123416248 123416350 103 - 0.211 0.998 3.844