ENSG00000156795

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000287387 ENSG00000156795 HEK293_OSMI2_2hA HEK293_TMG_2hB NTAQ1 protein_coding protein_coding 6.074569 6.02131 7.945095 0.7591066 0.8835799 0.3994078 1.8477594 2.5506314 2.064792 0.2866418 0.3265294 -0.3035325 0.33810000 0.4252667 0.2719333 -0.1533333 0.2264690835 1.07713e-05 FALSE  
ENST00000522194 ENSG00000156795 HEK293_OSMI2_2hA HEK293_TMG_2hB NTAQ1 protein_coding retained_intron 6.074569 6.02131 7.945095 0.7591066 0.8835799 0.3994078 0.7531649 0.3616142 2.378913 0.3616142 0.5326551 2.6844767 0.08416667 0.0511000 0.2916333 0.2405333 0.0856286372 1.07713e-05    
ENST00000523984 ENSG00000156795 HEK293_OSMI2_2hA HEK293_TMG_2hB NTAQ1 protein_coding protein_coding 6.074569 6.02131 7.945095 0.7591066 0.8835799 0.3994078 1.7940145 1.6591222 1.524939 0.3377285 0.7891090 -0.1209082 0.29549167 0.2804333 0.1959333 -0.0845000 0.7927291187 1.07713e-05 FALSE  
ENST00000524254 ENSG00000156795 HEK293_OSMI2_2hA HEK293_TMG_2hB NTAQ1 protein_coding protein_coding 6.074569 6.02131 7.945095 0.7591066 0.8835799 0.3994078 0.6344483 0.2435501 1.169758 0.2435501 0.6039380 2.2181485 0.09387083 0.0344000 0.1356333 0.1012333 0.5688161479 1.07713e-05 TRUE  
MSTRG.32053.14 ENSG00000156795 HEK293_OSMI2_2hA HEK293_TMG_2hB NTAQ1 protein_coding   6.074569 6.02131 7.945095 0.7591066 0.8835799 0.3994078 0.1293740 0.5112458 0.000000 0.1415605 0.0000000 -5.7038921 0.02705833 0.0914000 0.0000000 -0.0914000 0.0000107713 1.07713e-05 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000156795 E001 0.2965864 0.0928908857 0.261566052   8 123416695 123416725 31 + 0.000 0.206 10.175
ENSG00000156795 E002 2.0262317 0.0992269194 0.080085360 0.15968773 8 123416726 123416754 29 + 0.228 0.580 2.024
ENSG00000156795 E003 5.5520591 0.1136970994 0.182525819 0.30438161 8 123416755 123416770 16 + 0.648 0.895 0.995
ENSG00000156795 E004 5.4037660 0.1299210692 0.223832820 0.35499457 8 123416771 123416773 3 + 0.647 0.880 0.937
ENSG00000156795 E005 10.4014072 0.0195848933 0.859047181 0.91306069 8 123416774 123416791 18 + 1.041 1.059 0.064
ENSG00000156795 E006 12.4235165 0.0103110851 0.806916322 0.87734089 8 123416792 123416800 9 + 1.139 1.113 -0.092
ENSG00000156795 E007 13.3791556 0.0053386700 0.748273852 0.83555292 8 123416801 123416802 2 + 1.170 1.143 -0.099
ENSG00000156795 E008 15.9161613 0.0118956741 0.847913959 0.90557034 8 123416803 123416812 10 + 1.236 1.214 -0.077
ENSG00000156795 E009 22.8345331 0.0056698896 0.175280221 0.29503609 8 123416813 123416856 44 + 1.429 1.327 -0.353
ENSG00000156795 E010 16.9204539 0.0013092362 0.446852463 0.58831403 8 123416857 123416907 51 + 1.278 1.222 -0.197
ENSG00000156795 E011 12.7095400 0.0042352771 0.048355506 0.10625412 8 123416908 123416932 25 + 1.227 1.046 -0.649
ENSG00000156795 E012 38.0488676 0.0005430371 0.003776923 0.01251708 8 123427924 123428023 100 + 1.671 1.521 -0.511
ENSG00000156795 E013 23.9339974 0.0008540516 0.291426499 0.43229983 8 123429983 123429994 12 + 1.429 1.363 -0.228
ENSG00000156795 E014 31.9303621 0.0006385858 0.192513294 0.31691373 8 123429995 123430033 39 + 1.555 1.484 -0.243
ENSG00000156795 E015 0.1482932 0.0409082234 0.546614704   8 123430034 123430061 28 + 0.000 0.116 11.592
ENSG00000156795 E016 3.7843129 0.1061534544 0.985031259 0.99466037 8 123435442 123435542 101 + 0.682 0.689 0.030
ENSG00000156795 E017 48.4396357 0.0005667172 0.631325755 0.74634183 8 123436453 123436601 149 + 1.705 1.689 -0.055
ENSG00000156795 E018 56.8821690 0.0005097839 0.645459948 0.75755321 8 123437210 123437334 125 + 1.750 1.777 0.092
ENSG00000156795 E019 0.1472490 0.0447872167 0.437334061   8 123438134 123438238 105 + 0.129 0.000 -12.629
ENSG00000156795 E020 37.9743850 0.0006529375 0.436627521 0.57866924 8 123441306 123441349 44 + 1.613 1.577 -0.122
ENSG00000156795 E021 60.4532396 0.0003923604 0.040985320 0.09285402 8 123441350 123441497 148 + 1.731 1.826 0.321
ENSG00000156795 E022 83.8331250 0.0034543517 0.003349270 0.01128939 8 123441498 123442240 743 + 1.847 1.983 0.457
ENSG00000156795 E023 7.5600020 0.0118062371 0.810949437 0.88009451 8 123448047 123448224 178 + 0.934 0.908 -0.100
ENSG00000156795 E024 2.2841370 0.0065394659 0.415418851 0.55881289 8 123462655 123462761 107 + 0.435 0.575 0.677
ENSG00000156795 E025 1.5478799 0.0632707658 0.160412861 0.27568887 8 123463139 123463163 25 + 0.228 0.498 1.637
ENSG00000156795 E026 16.0359826 0.0031135124 0.390835278 0.53478102 8 123467079 123470028 2950 + 1.270 1.204 -0.230