ENSG00000156504

1 Isoform Switch

Summary Plot
Results

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Rows: 1-6 / 6
Columns:
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isoform_id
gene_id
condition_1
condition_2
gene_name
gene_biotype
iso_biotype
gene_overall_mean
gene_value_1
gene_value_2
gene_stderr_1
gene_stderr_2
gene_log2_fold_change
iso_overall_mean
iso_value_1
iso_value_2
iso_stderr_1
iso_stderr_2
iso_log2_fold_change
IF_overall
IF1
IF2
dIF
isoform_switch_q_value
gene_switch_q_value
PTC
codingPotential
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isoform_id	gene_id	condition_1	condition_2	gene_name	gene_biotype	iso_biotype	gene_overall_mean	gene_value_1	gene_value_2	gene_stderr_1	gene_stderr_2	gene_log2_fold_change	iso_overall_mean	iso_value_1	iso_value_2	iso_stderr_1	iso_stderr_2	iso_log2_fold_change	IF_overall	IF1	IF2	dIF	isoform_switch_q_value	gene_switch_q_value	PTC	codingPotential

ENST00000298090	ENSG00000156504	HEK293_OSMI2_2hA	HEK293_TMG_2hB	PABIR2	protein_coding	protein_coding	28.06967	28.98219	30.22247	1.926661	1.631383	0.06043449	4.669102	9.1497095	3.213496	1.92216177	0.7097052	-1.50667572	0.16526667	0.30973333	0.10450000	-0.205233333	0.001353646	1.242064e-16	FALSE	TRUE
ENST00000343004	ENSG00000156504	HEK293_OSMI2_2hA	HEK293_TMG_2hB	PABIR2	protein_coding	protein_coding	28.06967	28.98219	30.22247	1.926661	1.631383	0.06043449	5.143491	5.2703669	5.537738	0.46095134	0.4802081	0.07126155	0.18566250	0.18426667	0.18320000	-0.001066667	1.000000000	1.242064e-16	FALSE	TRUE
ENST00000370790	ENSG00000156504	HEK293_OSMI2_2hA	HEK293_TMG_2hB	PABIR2	protein_coding	protein_coding	28.06967	28.98219	30.22247	1.926661	1.631383	0.06043449	7.696445	7.7532516	7.127100	0.75924111	1.2623715	-0.12132314	0.27675417	0.26670000	0.23990000	-0.026800000	0.828276384	1.242064e-16	FALSE	TRUE
ENST00000486347	ENSG00000156504	HEK293_OSMI2_2hA	HEK293_TMG_2hB	PABIR2	protein_coding	protein_coding	28.06967	28.98219	30.22247	1.926661	1.631383	0.06043449	2.965522	3.0338140	4.510162	0.40307711	0.8875149	0.57049415	0.10467500	0.10763333	0.14810000	0.040466667	0.609483776	1.242064e-16	FALSE	TRUE
MSTRG.34922.17	ENSG00000156504	HEK293_OSMI2_2hA	HEK293_TMG_2hB	PABIR2	protein_coding		28.06967	28.98219	30.22247	1.926661	1.631383	0.06043449	1.799103	0.9684354	1.884436	0.50467213	0.3789886	0.95322018	0.06555833	0.03133333	0.06396667	0.032633333	0.631750128	1.242064e-16	FALSE	TRUE
MSTRG.34922.4	ENSG00000156504	HEK293_OSMI2_2hA	HEK293_TMG_2hB	PABIR2	protein_coding		28.06967	28.98219	30.22247	1.926661	1.631383	0.06043449	2.159964	0.6794563	2.763620	0.06603217	0.6883307	2.00823928	0.07677917	0.02336667	0.09430000	0.070933333	0.014482688	1.242064e-16	FALSE	TRUE

Note:
- The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

All exons whithin this gene region are shown and numbering below.

All isoforms whithin this gene region are shown below.

Rows: 1-10 / 31
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groupID
featureID
exonBaseMean
dispersion
pvalue
padj
seqnames
start
end
width
strand
HEK293_TMG_2hB
HEK293_OSMI2_2hA
log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
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groupID	featureID	exonBaseMean	dispersion	pvalue	padj	seqnames	start	end	width	strand	HEK293_TMG_2hB	HEK293_OSMI2_2hA	log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB

ENSG00000156504	E001	1.259497	0.3385440058	4.783825e-02	1.053350e-01	X	134769566	134769566	1	-	0.000	0.527	12.321
ENSG00000156504	E002	300.867562	0.0066365804	4.039813e-15	1.409448e-13	X	134769567	134769965	399	-	2.223	2.605	1.274
ENSG00000156504	E003	294.426830	0.0065507443	1.151887e-06	9.441100e-06	X	134769966	134770138	173	-	2.310	2.560	0.832
ENSG00000156504	E004	377.370309	0.0047162127	1.812126e-06	1.423307e-05	X	134770139	134770443	305	-	2.444	2.655	0.702
ENSG00000156504	E005	242.581601	0.0054281053	9.462774e-04	3.775683e-03	X	134770444	134770583	140	-	2.277	2.451	0.583
ENSG00000156504	E006	160.825203	0.0031624993	2.153493e-03	7.700267e-03	X	134770584	134770633	50	-	2.114	2.267	0.512
ENSG00000156504	E007	390.180436	0.0001661687	1.911970e-03	6.953143e-03	X	134770634	134770991	358	-	2.539	2.625	0.287
ENSG00000156504	E008	191.957439	0.0008161330	5.173512e-01	6.517574e-01	X	134770992	134771095	104	-	2.257	2.304	0.159
ENSG00000156504	E009	285.631365	0.0001702661	5.058121e-01	6.415385e-01	X	134771096	134771354	259	-	2.430	2.473	0.144
ENSG00000156504	E010	126.340654	0.0002695032	7.839992e-02	1.569189e-01	X	134771355	134771442	88	-	2.052	2.137	0.285
ENSG00000156504	E011	136.323818	0.0003012325	7.851334e-01	8.622492e-01	X	134771443	134771573	131	-	2.124	2.144	0.068
ENSG00000156504	E012	234.119130	0.0059136200	8.807819e-01	9.275545e-01	X	134771574	134771896	323	-	2.358	2.374	0.056
ENSG00000156504	E013	206.675047	0.0136243226	4.711780e-01	6.103262e-01	X	134771897	134772028	132	-	2.325	2.304	-0.071
ENSG00000156504	E014	121.243823	0.0126702614	1.060828e-01	1.997383e-01	X	134772029	134772078	50	-	2.128	2.047	-0.270
ENSG00000156504	E015	85.738337	0.0061417624	4.337213e-02	9.724504e-02	X	134772079	134772100	22	-	1.981	1.897	-0.282
ENSG00000156504	E016	124.252768	0.0040155251	9.298641e-02	1.797906e-01	X	134772101	134772142	42	-	2.122	2.073	-0.164
ENSG00000156504	E017	193.224541	0.0002158536	1.756520e-01	2.955333e-01	X	134772143	134772283	141	-	2.289	2.283	-0.020
ENSG00000156504	E018	193.101759	0.0003146797	1.704624e-02	4.503737e-02	X	134781821	134781917	97	-	2.302	2.268	-0.112
ENSG00000156504	E019	190.170548	0.0003519258	1.472117e-03	5.546258e-03	X	134785886	134785947	62	-	2.307	2.251	-0.187
ENSG00000156504	E020	78.822363	0.0013540074	3.078387e-04	1.411504e-03	X	134785948	134785950	3	-	1.966	1.839	-0.426
ENSG00000156504	E021	190.971021	0.0014032568	5.095306e-03	1.619106e-02	X	134787472	134787533	62	-	2.311	2.252	-0.197
ENSG00000156504	E022	204.643382	0.0003287532	1.168171e-08	1.423102e-07	X	134788730	134788831	102	-	2.370	2.253	-0.390
ENSG00000156504	E023	163.085110	0.0011048654	6.353458e-06	4.418987e-05	X	134789085	134789139	55	-	2.271	2.157	-0.381
ENSG00000156504	E024	149.140303	0.0006555653	4.403641e-04	1.929408e-03	X	134789223	134789266	44	-	2.214	2.134	-0.269
ENSG00000156504	E025	69.075049	0.0070817168	2.234785e-03	7.950522e-03	X	134789580	134789636	57	-	1.921	1.766	-0.523
ENSG00000156504	E026	13.635970	0.0021071670	1.126692e-02	3.180103e-02	X	134793803	134793814	12	-	1.260	1.055	-0.733
ENSG00000156504	E027	166.352354	0.0030424159	8.418263e-07	7.105750e-06	X	134793815	134793893	79	-	2.302	2.141	-0.539
ENSG00000156504	E028	137.725363	0.0004315578	2.468657e-10	4.068194e-09	X	134796108	134796211	104	-	2.225	2.057	-0.562
ENSG00000156504	E029	72.365253	0.0003736374	1.235135e-05	8.033808e-05	X	134796212	134796355	144	-	1.940	1.787	-0.515
ENSG00000156504	E030	153.006685	0.0035067310	7.622360e-07	6.497484e-06	X	134796356	134797120	765	-	2.272	2.101	-0.573
ENSG00000156504	E031	53.735083	0.0044604268	2.669350e-07	2.496299e-06	X	134797121	134797232	112	-	1.865	1.595	-0.915

Isoforom Switch Analysis

WANG Ziyi

Date: 19 5月 2022

ENSG00000156504

1 Isoform Switch

TableFilter v0.7.3

2 Differential Exon Usage

TableFilter v0.7.3