ENSG00000156502

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000359655 ENSG00000156502 HEK293_OSMI2_2hA HEK293_TMG_2hB SUPV3L1 protein_coding protein_coding 40.31169 48.16541 41.4509 6.960385 0.9641582 -0.2165457 25.31086 23.82019 29.61571 2.962760 0.5201249 0.314059 0.6241000 0.4980333 0.7152333 0.2172000 5.408655e-05 1.266158e-06 FALSE TRUE
ENST00000497254 ENSG00000156502 HEK293_OSMI2_2hA HEK293_TMG_2hB SUPV3L1 protein_coding processed_transcript 40.31169 48.16541 41.4509 6.960385 0.9641582 -0.2165457 11.49825 21.34121 7.02173 4.574224 0.9268266 -1.602366 0.2858292 0.4362000 0.1686667 -0.2675333 1.266158e-06 1.266158e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand HEK293_TMG_2hB HEK293_OSMI2_2hA log2fold_HEK293_OSMI2_2hA_HEK293_TMG_2hB
ENSG00000156502 E001 0.7760110 0.0163131486 6.445000e-01 7.567876e-01 10 69180192 69180233 42 + 0.294 0.219 -0.567
ENSG00000156502 E002 4.0157635 0.0044847250 4.131308e-01 5.566627e-01 10 69180234 69180249 16 + 0.767 0.663 -0.430
ENSG00000156502 E003 43.3270341 0.0119084874 4.948608e-02 1.082487e-01 10 69180250 69180280 31 + 1.719 1.572 -0.498
ENSG00000156502 E004 58.3696756 0.0168977280 5.600799e-02 1.197092e-01 10 69180281 69180287 7 + 1.848 1.695 -0.514
ENSG00000156502 E005 214.8452604 0.0112745552 7.138612e-03 2.158400e-02 10 69180288 69180562 275 + 2.410 2.255 -0.520
ENSG00000156502 E006 15.9740552 0.0372963512 1.766019e-01 2.968322e-01 10 69182520 69182654 135 + 1.309 1.135 -0.615
ENSG00000156502 E007 136.5776458 0.0048709333 2.433922e-02 6.051487e-02 10 69185987 69186064 78 + 2.189 2.090 -0.330
ENSG00000156502 E008 162.4953802 0.0023279189 4.342119e-02 9.733430e-02 10 69186443 69186550 108 + 2.249 2.184 -0.217
ENSG00000156502 E009 0.4783925 0.0222186323 5.666936e-01 6.936238e-01 10 69187433 69187466 34 + 0.217 0.123 -0.980
ENSG00000156502 E010 162.9993129 0.0044268896 2.677346e-01 4.060742e-01 10 69187642 69187712 71 + 2.238 2.196 -0.141
ENSG00000156502 E011 155.1696819 0.0002692237 3.370083e-04 1.528421e-03 10 69187713 69187756 44 + 2.244 2.154 -0.301
ENSG00000156502 E012 274.7736692 0.0002287904 1.406049e-04 7.061115e-04 10 69189267 69189435 169 + 2.481 2.411 -0.234
ENSG00000156502 E013 210.4501602 0.0002174660 2.359232e-03 8.336120e-03 10 69191655 69191766 112 + 2.361 2.298 -0.209
ENSG00000156502 E014 58.8539497 0.0005645550 2.254392e-01 3.569358e-01 10 69191767 69193263 1497 + 1.740 1.808 0.228
ENSG00000156502 E015 172.8661815 0.0002229837 7.860562e-04 3.209465e-03 10 69195188 69195265 78 + 2.285 2.207 -0.260
ENSG00000156502 E016 2.4601711 0.0841290626 3.049682e-02 7.294218e-02 10 69195266 69195380 115 + 0.717 0.297 -2.105
ENSG00000156502 E017 209.6215138 0.0002122237 2.277894e-04 1.082449e-03 10 69196992 69197083 92 + 2.368 2.290 -0.260
ENSG00000156502 E018 286.8682908 0.0013141080 4.524329e-02 1.006341e-01 10 69198372 69198552 181 + 2.486 2.442 -0.146
ENSG00000156502 E019 182.2493694 0.0027032606 9.354907e-01 9.633956e-01 10 69199104 69199197 94 + 2.264 2.269 0.018
ENSG00000156502 E020 346.1922962 0.0001701002 6.515875e-01 7.624257e-01 10 69200280 69200499 220 + 2.535 2.556 0.069
ENSG00000156502 E021 198.4181101 0.0016053275 3.470655e-03 1.164097e-02 10 69202439 69202519 81 + 2.247 2.348 0.339
ENSG00000156502 E022 345.2518690 0.0003401761 6.255250e-06 4.355958e-05 10 69202867 69203043 177 + 2.487 2.590 0.343
ENSG00000156502 E023 2.5998271 0.0876520060 7.459016e-01 8.338049e-01 10 69207776 69207792 17 + 0.514 0.593 0.366
ENSG00000156502 E024 417.5561872 0.0021425990 1.748654e-05 1.098983e-04 10 69207793 69207941 149 + 2.552 2.678 0.418
ENSG00000156502 E025 636.5893535 0.0022301054 5.210870e-09 6.776384e-08 10 69208600 69209099 500 + 2.718 2.869 0.500